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Select item 111594401.

Induction of a novel histone deacetylase 1/c‐Myc/Mnt/Max complex formation is implicated in parity‐induced refractoriness to mammary carcinogenesis

Yoichiro Matsuoka, Katsumi Fukamachi, Norihisa Uehara, Hiroyuki Tsuda, Airo Tsubura

Cancer Sci. 2008 Feb; 99(2): 309–315. Published online 2008 Feb 6. doi: 10.1111/j.1349-7006.2007.00689.x

PMCID:: PMC11159440

Abstract Article PDF–191K

Select item 111481842.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 108067383.

A recurrent de novo MAX p.Arg60Gln variant causes a syndromic overgrowth disorder through differential expression of c-Myc target genes

Erica L. Harris, Vincent Roy, Martin Montagne, Ailsa M.S. Rose, Helen Livesey, Margot R.F. Reijnders, Emma Hobson, Francis H. Sansbury, Marjolein H. Willemsen, Rolph Pfundt, Daniel Warren, Vernon Long, Ian M. Carr, Han G. Brunner, Eamonn G. Sheridan, Helen V. Firth, Pierre Lavigne, James A. Poulter

Am J Hum Genet. 2024 Jan 4; 111(1): 119–132. Published online 2023 Dec 22. doi: 10.1016/j.ajhg.2023.11.010

PMCID:: PMC10806738

Abstract Article PDF–4.9M

Select item 107315004.

NMR‐identification of the interaction between BRCA1 and the intrinsically disordered monomer of the Myc‐associated factor X

Ludovica Martina Epasto, Christopher Pötzl, Herwig Peterlik, Mahdi Khalil, Christine Saint‐Pierre, Didier Gasparutto, Giuseppe Sicoli, Dennis Kurzbach

Protein Sci. 2024 Jan; 33(1): e4849. Published online 2024 Jan 1. doi: 10.1002/pro.4849

PMCID:: PMC10731500

Abstract Article PDF–842K

Select item 101381915.

Validation of Myc-Associated Protein X (MAX) regulation in growth hormone secreting and nonfunctional pituitary adenoma

Douglass W. Tucker, Dhiraj J. Pangal, Robin Du, Angad S. Gogia, Ali Tafreshi, Jacob Ruzevick, Kyle T. Hurth, Tim Triche, Jr, Alexander Micko, John D. Carpten, Mark S. Shiroishi, John D. Carmichael, Suhn K. Rhie, Gabriel Zada

PLoS One. 2023; 18(4): e0284949. Published online 2023 Apr 27. doi: 10.1371/journal.pone.0284949

PMCID:: PMC10138191

Abstract Article PDF–1.6M

Select item 99849016.

P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma

Cheng Cheng, Tian He, Kai Chen, Yuanxia Cai, Yaoyao Gu, Lijia Pan, Peiwen Duan, Yeming Wu, Zhixiang Wu

Mol Cell Proteomics. 2023 Mar; 22(3): 100504. Published online 2023 Jan 26. doi: 10.1016/j.mcpro.2023.100504

PMCID:: PMC9984901

Abstract Article PDF–4.3M

Select item 98831697.

Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma

Xi-Ya Li, Ji-Chuan Wu, Ping Liu, Zi-Juan Li, Yong Wang, Bing-Yi Chen, Cheng-Long Hu, Ming-Yue Fei, Peng-Cheng Yu, Yi-Lun Jiang, Chun-Hui Xu, Bin-He Chang, Xin-Chi Chen, Li-Juan Zong, Jia-Ying Zhang, Ying Fang, Xiao-Jian Sun, Kai Xue, Li Wang, Shu-Bei Chen, Shi-Yu Jiang, Ai-ling Gui, Ling Yang, Juan J. Gu, Bao-Hua Yu, Qun-ling Zhang, Lan Wang

Leukemia. 2023; 37(1): 164–177. Published online 2022 Nov 9. doi: 10.1038/s41375-022-01747-2

PMCID:: PMC9883169

Abstract Article PDF–6.6M

Select item 97105138.

EZH2 non-canonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis

Jun Wang, Xufen Yu, Weida Gong, Xijuan Liu, Kwang-Su Park, Anqi Ma, Yi-Hsuan Tsai, Yudao Shen, Takashi Onikubo, Wen-Chieh Pi, David F. Allison, Jing Liu, Wei-Yi Chen, Ling Cai, Robert G. Roeder, Jian Jin, Gang Greg Wang

Nat Cell Biol. Author manuscript; available in PMC 2022 Nov 30.

Published in final edited form as: Nat Cell Biol. 2022 Mar; 24(3): 384–399. Published online 2022 Feb 24. doi: 10.1038/s41556-022-00850-x

PMCID:: PMC9710513

Abstract Article PDF–7.9M

Select item 95403459.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 951364610.

Succinate dehydrogenase and MYC-associated factor X mutations in pituitary neuroendocrine tumours

Paul Benjamin Loughrey, Federico Roncaroli, Estelle Healy, Philip Weir, Madhu Basetti, Ruth T Casey, Steven J Hunter, Márta Korbonits

Endocr Relat Cancer. 2022 Oct 1; 29(10): R157–R172. Published online 2022 Aug 8. doi: 10.1530/ERC-22-0157

PMCID:: PMC9513646

Abstract Article PDF–3.1M

Select item 943659211.

miR-22 Suppresses EMT by Mediating Metabolic Reprogramming in Colorectal Cancer through Targeting MYC-Associated Factor X

Shusen Xia, Xianyan Wang, Yi Wu, Tong Zhou, Hongpeng Tian, Zuoliang Liu, Lifa Li, Zaihua Yan, Guangjun Zhang

Dis Markers. 2022; 2022: 7843565. Published online 2022 Aug 25. doi: 10.1155/2022/7843565

PMCID:: PMC9436592

Abstract Article PDF–3.9M

Select item 936044312.

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3

PMCID:: PMC9360443

Abstract Article PDF–5.8M

Select item 935700313.

PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression

Xianchun Lan, Song Ding, Tianzhe Zhang, Ying Yi, Conghui Li, Wenwen Jin, Jian Chen, Kaiwei Liang, Hengbin Wang, Wei Jiang

Nat Commun. 2022; 13: 4601. Published online 2022 Aug 6. doi: 10.1038/s41467-022-32295-z

PMCID:: PMC9357003

Abstract Article PDF–3.7M

Select item 927928514.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973615.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910630316.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 906562917.

Functional inhibition of c-Myc using novel inhibitors identified through “hot spot” targeting

Ashutosh Singh, Prateek Kumar, Sailu Sarvagalla, Taniya Bharadwaj, Namyashree Nayak, Mohane Selvaraj Coumar, Rajanish Giri, Neha Garg

J Biol Chem. 2022 May; 298(5): 101898. Published online 2022 Apr 1. doi: 10.1016/j.jbc.2022.101898

PMCID:: PMC9065629

Abstract Article PDF–4.5M

Select item 903542018.

MAX deficiency impairs human endometrial decidualization through down-regulating OSR2 in women with recurrent spontaneous abortion

Weixu Ma, Mingzhu Cao, Shilei Bi, Lili Du, Jingsi Chen, Haibin Wang, Yufei Jiang, Yixuan Wu, Yixin Liao, Shuangbo Kong, Jianqiao Liu

Cell Tissue Res. 2022; 388(2): 453–469. Published online 2022 Feb 11. doi: 10.1007/s00441-022-03579-z

PMCID:: PMC9035420

Abstract Article PDF–12M

Select item 900533219.

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity

Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan

Science. Author manuscript; available in PMC 2022 Apr 13.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911

PMCID:: PMC9005332

Abstract Article PDF–2.0M

Select item 882889520.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

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PMC Links for GEO Profiles (Select 12593087) (140)
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Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)
Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)
Accession: GDS1333

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Lung pneumocyte response to Pseudomonas aeruginosa type III secretion system mut...
Lung pneumocyte response to Pseudomonas aeruginosa type III secretion system mutants
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