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Items: 1 to 20 of 23

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
3.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
4.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
5.
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629
PMCID:
PMC8842165
AbstractArticlePDF–3.0M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Human Gb3/CD77 synthase produces P1 glycotope-capped N-glycans, which mediate Shiga toxin 1 but not Shiga toxin 2 cell entry
Katarzyna Szymczak-Kulus, Sascha Weidler, Anna Bereznicka, Krzysztof Mikolajczyk, Radoslaw Kaczmarek, Bartosz Bednarz, Tao Zhang, Anna Urbaniak, Mariusz Olczak, Enoch Y. Park, Edyta Majorczyk, Katarzyna Kapczynska, Jolanta Lukasiewicz, Manfred Wuhrer, Carlo Unverzagt, Marcin Czerwinski
J Biol Chem. 2021 Jan-Jun; 296: 100299. Published online 2021 Jan 15. doi: 10.1016/j.jbc.2021.100299
PMCID:
PMC7949097
AbstractArticlePDF–3.2M
8.
The interaction between flagellin and the glycosphingolipid Gb3 on host cells contributes to Bacillus cereus acute infection
Song Gao, Chengpei Ni, Wenhua Huang, Huaijie Hao, Hua Jiang, Qingyu Lv, Yuling Zheng, Peng Liu, Decong Kong, Yongqiang Jiang
Virulence. 2020; 11(1): 769–780. Published online 2020 Jun 7. doi: 10.1080/21505594.2020.1773077
PMCID:
PMC7567440
AbstractArticlePDF–2.5M
9.
The synonymous 903C>G mutation in the alpha 1,4-galactosyltransferase gene in a Chinese woman with habitual abortion: A case report
Xiaoying Lv, Yongquan Chen, Yuanyuan Luo, Lingbo Li, Houzhao Wang
Medicine (Baltimore) 2019 Aug; 98(31): e16361. Published online 2019 Aug 2. doi: 10.1097/MD.0000000000016361
Correction in:
Medicine (Baltimore). 2019 Aug; 98(33): e16971.
PMCID:
PMC6709120
AbstractArticlePDF–270K
10.
Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system
Radoslaw Kaczmarek, Katarzyna Szymczak-Kulus, Anna Bereźnicka, Krzysztof Mikołajczyk, Maria Duk, Edyta Majorczyk, Anna Krop-Watorek, Elżbieta Klausa, Joanna Skowrońska, Bogumiła Michalewska, Ewa Brojer, Marcin Czerwinski
PLoS One. 2018; 13(4): e0196627. Published online 2018 Apr 30. doi: 10.1371/journal.pone.0196627
PMCID:
PMC5927444
AbstractArticlePDF–7.7M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
Evaluation of an amino acid residue critical for the specificity and activity of human Gb3/CD77 synthase
Radoslaw Kaczmarek, Katarzyna Mikolajewicz, Katarzyna Szymczak, Maria Duk, Edyta Majorczyk, Anna Krop-Watorek, Anna Buczkowska, Marcin Czerwinski
Glycoconj J. 2016; 33(6): 963–973. Published online 2016 Aug 18. doi: 10.1007/s10719-016-9716-9
PMCID:
PMC5149393
AbstractArticlePDF–2.0M
13.
Widespread expansion of protein interaction capabilities by alternative splicing
Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal
Cell. Author manuscript; available in PMC 2017 Feb 11.
Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029
PMCID:
PMC4882190
AbstractArticlePDF–1.9M
14.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
15.
A Single Point Mutation in the Gene Encoding Gb3/CD77 Synthase Causes a Rare Inherited Polyagglutination Syndrome
Anna Suchanowska, Radoslaw Kaczmarek, Maria Duk, Jolanta Lukasiewicz, Dorota Smolarek, Edyta Majorczyk, Ewa Jaskiewicz, Anna Laskowska, Kazimiera Wasniowska, Magdalena Grodecka, Elwira Lisowska, Marcin Czerwinski
J Biol Chem. 2012 Nov 2; 287(45): 38220–38230. Published online 2012 Sep 10. doi: 10.1074/jbc.M112.408286
Correction in:
J Biol Chem. 2013 Jan 4; 288(1): 294.
PMCID:
PMC3488091
AbstractArticlePDF–1.8M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Increased globotriaosylceramide levels in a transgenic mouse expressing human α1,4-galactosyltransferase and a mouse model for treating Fabry disease
Chikara Shiozuka, Atsumi Taguchi, Junichiro Matsuda, Yoko Noguchi, Takanori Kunieda, Kozue Uchio-Yamada, Hidekatsu Yoshioka, Ryoji Hamanaka, Shinji Yano, Shigeo Yokoyama, Kazuaki Mannen, Ashok B. Kulkarni, Koichi Furukawa, Satoshi Ishii
J Biochem. 2011 Feb; 149(2): 161–170. Published online 2010 Oct 19. doi: 10.1093/jb/mvq125
PMCID:
PMC3031308
AbstractArticlePDF–517K
18.
Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide
Steven D. Zumbrun, Leanne Hanson, James F. Sinclair, James Freedy, Angela R. Melton-Celsa, Jaime Rodriguez-Canales, Jeffrey C. Hanson, Alison D. O'Brien
Infect Immun. 2010 Nov; 78(11): 4488–4499. Published online 2010 Aug 23. doi: 10.1128/IAI.00620-10
PMCID:
PMC2976364
AbstractArticlePDF–3.0M
19.
Transmembrane BAX Inhibitor Motif Containing (TMBIM) Family Proteins Perturbs a trans-Golgi Network Enzyme, Gb3 Synthase, and Reduces Gb3 Biosynthesis
Toshiyuki Yamaji, Kiyotaka Nishikawa, Kentaro Hanada
J Biol Chem. 2010 Nov 12; 285(46): 35505–35518. Published online 2010 Sep 13. doi: 10.1074/jbc.M110.154229
PMCID:
PMC2975175
AbstractArticlePDF–4.6M
20.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K

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