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Items: 1 to 20 of 46

1.
Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity
Md Rasel Molla, Akio Shimizu, Masahiro Komeno, Nor Idayu A. Rahman, Joanne Ern Chi Soh, Le Kim Chi Nguyen, Mahbubur Rahman Khan, Wondwossen Wale Tesega, Si Chen, Xiaoling Pang, Miki Tanaka-Okamoto, Noriyuki Takashima, Akira Sato, Tomoaki Suzuki, Hisakazu Ogita
Commun Biol. 2022; 5: 1071. Published online 2022 Oct 7. doi: 10.1038/s42003-022-04042-z
PMCID:
PMC9546906
AbstractArticlePDF–5.3M
2.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
3.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
The Ste20 Family Kinases MAP4K4, MINK1, and TNIK Converge to Regulate Stress-Induced JNK Signaling in Neurons
Martin Larhammar, Sarah Huntwork-Rodriguez, York Rudhard, Arundhati Sengupta-Ghosh, Joseph W. Lewcock
J Neurosci. 2017 Nov 15; 37(46): 11074–11084. doi: 10.1523/JNEUROSCI.0905-17.2017
PMCID:
PMC6596808
AbstractArticlePDF–4.0M
7.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
8.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
9.
RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis
Hui-Yu Peng, Yu-Chih Liang, Tse-Hua Tan, Huai-Chia Chuang, Ying-Ju Lin, Jung-Chun Lin
Int J Mol Sci. 2018 Sep; 19(9): 2646. Published online 2018 Sep 6. doi: 10.3390/ijms19092646
PMCID:
PMC6163301
AbstractArticlePDF–2.7M
10.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
11.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
12.
Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity
Rachel J. Roth Flach, Marina T. DiStefano, Laura V. Danai, Ozlem Senol-Cosar, Joseph C. Yawe, Mark Kelly, Lorena Garcia Menendez, Michael P. Czech
Am J Physiol Endocrinol Metab. 2017 Sep 1; 313(3): E303–E313. Published online 2017 Jun 13. doi: 10.1152/ajpendo.00037.2017
PMCID:
PMC5625083
AbstractArticle
13.
FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway
Jinpeng Li, Sen Shi, Swayam Prakash Srivastava, Munehiro Kitada, Takako Nagai, Kyoko Nitta, Miyuki Kohno, Keizo Kanasaki, Daisuke Koya
Cell Death Dis. 2017 Aug; 8(8): e2965. Published online 2017 Aug 3. doi: 10.1038/cddis.2017.353
PMCID:
PMC5596544
AbstractArticlePDF–3.0M
14.
Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia
Rachel J. Roth Flach, Laura V. Danai, Marina T. DiStefano, Mark Kelly, Lorena Garcia Menendez, Agata Jurczyk, Rohit B. Sharma, Dae Young Jung, Jong Hun Kim, Jason K. Kim, Rita Bortell, Laura C. Alonso, Michael P. Czech
J Biol Chem. 2016 Jul 29; 291(31): 16221–16230. Published online 2016 May 20. doi: 10.1074/jbc.M116.718932
PMCID:
PMC4965570
AbstractArticlePDF–1.4M
15.
Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function
Rachel J. Roth Flach, Chang-An Guo, Laura V. Danai, Joseph C. Yawe, Sharvari Gujja, Yvonne J. K. Edwards, Michael P. Czech
Mol Cell Biol. 2016 Jun 15; 36(12): 1740–1749. Prepublished online 2016 Apr 4. Published online 2016 May 31. doi: 10.1128/MCB.01121-15
PMCID:
PMC4907094
AbstractArticlePDF–2.7M
16.
UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts
Jianqiang Bao, Kristoffer Vitting-Seerup, Johannes Waage, Chong Tang, Ying Ge, Bo T. Porse, Wei Yan
PLoS Genet. 2016 May; 12(5): e1005863. Published online 2016 May 5. doi: 10.1371/journal.pgen.1005863
PMCID:
PMC4858225
AbstractArticlePDF–20M
17.
Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis
Rachel J. Roth Flach, Athanasia Skoura, Anouch Matevossian, Laura V. Danai, Wei Zheng, Christian Cortes, Samit K. Bhattacharya, Myriam Aouadi, Nana Hagan, Joseph C. Yawe, Pranitha Vangala, Lorena Garcia Menendez, Marcus P. Cooper, Timothy P. Fitzgibbons, Leonard Buckbinder, Michael P. Czech
Nat Commun. 2015; 6: 8995. Published online 2015 Dec 21. doi: 10.1038/ncomms9995
PMCID:
PMC4703891
AbstractArticlePDF–1.5M
18.
Inducible Deletion of Protein Kinase Map4k4 in Obese Mice Improves Insulin Sensitivity in Liver and Adipose Tissues
Laura V. Danai, Rachel J. Roth Flach, Joseph V. Virbasius, Lorena Garcia Menendez, Dae Young Jung, Jong Hun Kim, Jason K. Kim, Michael P. Czech
Mol Cell Biol. 2015 Jul; 35(13): 2356–2365. Prepublished online 2015 Apr 27. Published online 2015 Jun 4. doi: 10.1128/MCB.00150-15
PMCID:
PMC4456439
AbstractArticlePDF–2.7M
19.
Real-time resolution of point mutations that cause phenovariance in mice
Tao Wang, Xiaowei Zhan, Chun-Hui Bu, Stephen Lyon, David Pratt, Sara Hildebrand, Jin Huk Choi, Zhao Zhang, Ming Zeng, Kuan-wen Wang, Emre Turer, Zhe Chen, Duanwu Zhang, Tao Yue, Ying Wang, Hexin Shi, Jianhui Wang, Lei Sun, Jeff SoRelle, William McAlpine, Noelle Hutchins, Xiaoming Zhan, Maggy Fina, Rochelle Gobert, Jiexia Quan, McKensie Kreutzer, Stephanie Arnett, Kimberly Hawkins, Ashley Leach, Christopher Tate, Chad Daniel, Carlos Reyna, Lauren Prince, Sheila Davis, Joel Purrington, Rick Bearden, Jennifer Weatherly, Danielle White, Jamie Russell, Qihua Sun, Miao Tang, Xiaohong Li, Lindsay Scott, Eva Marie Y. Moresco, Gerald M. McInerney, Gunilla B. Karlsson Hedestam, Yang Xie, Bruce Beutler
Proc Natl Acad Sci U S A. 2015 Feb 3; 112(5): E440–E449. Published online 2015 Jan 20. doi: 10.1073/pnas.1423216112
PMCID:
PMC4321302
AbstractArticlePDF–1.6M
20.
The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit
Lawrence L. LeClaire, Manish Rana, Martin Baumgartner, Diane L. Barber
J Cell Biol. 2015 Jan 19; 208(2): 161–170. doi: 10.1083/jcb.201404095
PMCID:
PMC4298681
AbstractArticlePDF–2.6M

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