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Select item 109397421.

DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER

Shunxing Rong, Mingfeng Xia, Goncalo Vale, Simeng Wang, Chai-Wan Kim, Shili Li, Jeffrey G. McDonald, Arun Radhakrishnan, Jay D. Horton

Cell Metab. Author manuscript; available in PMC 2024 Mar 14.

Published in final edited form as: Cell Metab. 2024 Mar 5; 36(3): 617–629.e7. Published online 2024 Feb 9. doi: 10.1016/j.cmet.2024.01.011

PMCID:: PMC10939742

Abstract Article PDF–1.7M

Select item 107725592.

Role of Dgat2 in Glucose Uptake and Fatty Acid Metabolism in C2C12 Skeletal Myotubes

So Young Bu

J Microbiol Biotechnol. 2023 Dec 28; 33(12): 1563–1575. Published online 2023 Aug 18. doi: 10.4014/jmb.2307.07018

PMCID:: PMC10772559

Abstract Article PDF–2.4M

Select item 101469003.

ZFP750 affects the cutaneous barrier through regulating lipid metabolism

Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli, Lorenzo D’Ambrosio, Laura Falasca, Roberta Nardacci, Lu Wang, Mauro Piacentini, Richard A. Knight, Wei Jia, Qiang Sun, Yufang Shi, Ying Wang, Eleonora Candi, Gerry Melino

Sci Adv. 2023 Apr; 9(17): eadg5423. Published online 2023 Apr 28. doi: 10.1126/sciadv.adg5423

PMCID:: PMC10146900

Abstract Article PDF–2.3M

Select item 85399914.

Histone Demethylase KDM7A Contributes to the Development of Hepatic Steatosis by Targeting Diacylglycerol Acyltransferase 2

Ji-Hyun Kim, Arukumar Nagappan, Dae Young Jung, Nanjoo Suh, Myeong Ho Jung

Int J Mol Sci. 2021 Oct; 22(20): 11085. Published online 2021 Oct 14. doi: 10.3390/ijms222011085

PMCID:: PMC8539991

Abstract Article PDF–3.0M

Select item 84237495.

Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding

Fangjun Yu, Zhigang Wang, Tianpeng Zhang, Xun Chen, Haiman Xu, Fei Wang, Lianxia Guo, Min Chen, Kaisheng Liu, Baojian Wu

Nat Commun. 2021; 12: 5323. Published online 2021 Sep 7. doi: 10.1038/s41467-021-25674-5

PMCID:: PMC8423749

Abstract Article PDF–2.4M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77222437.

CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4α and DGAT2 expression

Stefanie Y. Tan, Hannah C. Little, Dylan C. Sarver, Paul A. Watkins, G. William Wong

FEBS Lett. Author manuscript; available in PMC 2020 Dec 8.

Published in final edited form as: FEBS Lett. 2020 Oct; 594(19): 3227–3239. Published online 2020 Aug 14. doi: 10.1002/1873-3468.13895

PMCID:: PMC7722243

Abstract Article PDF–1.0M

Select item 76966568.

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

Chandramohan Chitraju, Alexander W. Fischer, Robert V. Farese, Jr., Tobias C. Walther

Cell Rep. Author manuscript; available in PMC 2020 Nov 28.

Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108348. doi: 10.1016/j.celrep.2020.108348

PMCID:: PMC7696656

Abstract Article PDF–1.6M

Select item 73052299.

The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease

Timothy E. Thayer, Christian L. Lino Cardenas, Trejeeve Martyn, Christopher J. Nicholson, Lisa Traeger, Florian Wunderer, Charles Slocum, Haakon Sigurslid, Hannah R. Shakartzi, Caitlin O’Rourke, Georgia Shelton, Mary D. Buswell, Hanna Barnes, Leif R. Neitzel, Clara D. Ledsky, Jason Pingcheng Li, Megan F. Burke, Eric Farber-Eger, Daniel S. Perrien, Ravindra Kumar, Kathleen E. Corey, Quinn S. Wells, Kenneth D. Bloch, Charles C. Hong, Donald B. Bloch, Rajeev Malhotra

Sci Rep. 2020; 10: 9831. Published online 2020 Jun 19. doi: 10.1038/s41598-020-66770-8

PMCID:: PMC7305229

Abstract Article PDF–5.0M

Select item 705725810.

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez

Cell Rep. 2019 Nov 5; 29(6): 1410–1418.e6. Published online 2019 Nov 5. doi: 10.1016/j.celrep.2019.09.073

PMCID:: PMC7057258

Abstract Article

Select item 689391311.

Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice

Nina L. Gluchowski, Katlyn R. Gabriel, Chandramohan Chitraju, Roderick T. Bronson, Niklas Mejhert, Sebastian Boland, Kun Wang, Zon Weng Lai, Robert V. Farese, Jr., Tobias C. Walther

Hepatology. Author manuscript; available in PMC 2019 Dec 5.

Published in final edited form as: Hepatology. 2019 Dec; 70(6): 1972–1985. Published online 2019 Jun 26. doi: 10.1002/hep.30765

PMCID:: PMC6893913

Abstract Article PDF–2.2M

Select item 654763512.

The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes

Chandramohan Chitraju, Tobias C. Walther, Robert V. Farese, Jr.

J Lipid Res. 2019 Jun; 60(6): 1112–1120. Published online 2019 Apr 1. doi: 10.1194/jlr.M093112

PMCID:: PMC6547635

Abstract Article PDF–1.4M

Select item 651836813.

Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice

Doris Kaltenecker, Kristina M. Mueller, Pia Benedikt, Ursula Feiler, Madeleine Themanns, Michaela Schlederer, Lukas Kenner, Martina Schweiger, Guenter Haemmerle, Richard Moriggl

Diabetologia. 2017; 60(2): 296–305. Published online 2016 Nov 17. doi: 10.1007/s00125-016-4152-8

PMCID:: PMC6518368

Abstract Article PDF–1.3M

Select item 631425814.

Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2

Zehra Irshad, Nikola Chmel, Raghu Adya, Victor A. Zammit

J Lipid Res. 2019 Jan; 60(1): 111–120. Published online 2018 Nov 5. doi: 10.1194/jlr.M089300

PMCID:: PMC6314258

Abstract Article PDF–952K

Select item 586287915.

The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function

Nathan D. Roe, Michal K. Handzlik, Tao Li, Rong Tian

Sci Rep. 2018; 8: 4983. Published online 2018 Mar 21. doi: 10.1038/s41598-018-23223-7

PMCID:: PMC5862879

Abstract Article PDF–2.0M

Select item 550321416.

Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat

Yu-Han Hung, Alicia L. Carreiro, Kimberly K. Buhman

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Jun; 1862(6): 600–614. Published online 2017 Feb 27. doi: 10.1016/j.bbalip.2017.02.014

PMCID:: PMC5503214

Abstract Article PDF–2.0M

Select item 523470817.

Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes

Zehra Irshad, Federica Dimitri, Mark Christian, Victor A. Zammit

J Lipid Res. 2017 Jan; 58(1): 15–30. Published online 2016 Dec 29. doi: 10.1194/jlr.M068197

PMCID:: PMC5234708

Abstract Article PDF–1.6M

Select item 513335218.

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation

Sandip K. Bose, Irina Hutson, Charles A. Harris

Endocrinology. 2016 Dec; 157(12): 4943–4960. Published online 2016 Oct 18. doi: 10.1210/en.2016-1615

PMCID:: PMC5133352

Abstract Article

Select item 505975019.

An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation

Gabriela Segerer, Kerstin Hadamek, Matthias Zundler, Agnes Fekete, Annegrit Seifried, Martin J. Mueller, Frank Koentgen, Manfred Gessler, Elisabeth Jeanclos, Antje Gohla

Sci Rep. 2016; 6: 35160. Published online 2016 Oct 12. doi: 10.1038/srep35160

PMCID:: PMC5059750

Abstract Article PDF–2.6M

Select item 465317520.

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity

Tatiana L. Fonseca, Gustavo W. Fernandes, Elizabeth A. McAninch, Barbara M. L. C. Bocco, Sherine M. Abdalla, Miriam O. Ribeiro, Petra Mohácsik, Csaba Fekete, Daofeng Li, Xiaoyun Xing, Ting Wang, Balázs Gereben, Antonio C. Bianco

Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45): 14018–14023. Published online 2015 Oct 27. doi: 10.1073/pnas.1508943112

PMCID:: PMC4653175

Abstract Article PDF–1.0M

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