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Items: 1 to 20 of 30

1.
Kallikrein augments the anticoagulant function of the protein C system in thrombin generation
Jun Wan, Nadira Vadaq, Joke Konings, Martin Jaeger, Vinod Kumar, Bas de Laat, Leo Joosten, Mihai G. Netea, Andre J. van der Ven, Philip G. de Groot, Quirijn de Mast, Mark Roest
J Thromb Haemost. 2022 Jan; 20(1): 48–57. Published online 2021 Sep 28. doi: 10.1111/jth.15530
PMCID:
PMC9293419
AbstractArticlePDF–1.6M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Prospective study of plasma high molecular weight kininogen and prekallikrein and incidence of coronary heart disease, ischemic stroke and heart failure
Romil R. Parikh, Aaron R. Folsom, Jeffrey R. Misialek, Wayne D. Rosamond, Patricia P. Chang, Weihong Tang, Mary Cushman
Thromb Res. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Thromb Res. 2019 Oct; 182: 89–94. Published online 2019 Aug 22. doi: 10.1016/j.thromres.2019.08.009
PMCID:
PMC6825898
AbstractArticlePDF–259K
4.
Kallikrein Cleaves C3 and Activates Complement
Sarah Irmscher, Nadia Döring, Luke D. Halder, Emeraldo A.H. Jo, Isabell Kopka, Christine Dunker, Ilse D. Jacobsen, Shanshan Luo, Hortense Slevogt, Stefan Lorkowski, Niklas Beyersdorf, Peter F. Zipfel, Christine Skerka
J Innate Immun. 2018 Mar; 10(2): 94–105. Published online 2017 Dec 14. doi: 10.1159/000484257
PMCID:
PMC6757171
AbstractArticlePDF–571K
5.
IONIS-PKKRx a Novel Antisense Inhibitor of Prekallikrein and Bradykinin Production
Jason D. Ferrone, Gourab Bhattacharjee, Alexey S. Revenko, Thomas A. Zanardi, Marshelle S. Warren, Frederick J. Derosier, Nicholas J. Viney, Nguyen C. Pham, Gwendolyn E. Kaeser, Brenda F. Baker, Eugene Schneider, Steven G. Hughes, Brett P. Monia, A. Robert MacLeod
Nucleic Acid Ther. 2019 Apr 1; 29(2): 82–91. Published online 2019 Mar 29. doi: 10.1089/nat.2018.0754
PMCID:
PMC6461157
AbstractArticlePDF–403K
6.
PKK deletion in basal keratinocytes promotes tumorigenesis after chemical carcinogenesis
Luojing Chen, Matthew S Hayden, Elaine S Gilmore, Carolina Alexander-Savino, David Oleksyn, Kathleen Gillespie, Jiyong Zhao, Brian Poligone
Carcinogenesis. 2018 Mar; 39(3): 418–428. Published online 2017 Nov 22. doi: 10.1093/carcin/bgx120
PMCID:
PMC6454431
AbstractArticlePDF–9.1M
7.
A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert
Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289
PMCID:
PMC6298254
AbstractArticlePDF–1.4M
8.
Nucleic Acids as Cofactors for Factor XI and Prekallikrein Activation: Different roles for high molecular weight kininogen
Ivan Ivanov, Ruhama Shakhawat, Mao-fu Sun, S. Kent Dickeson, Cristina Puy, Owen J.T. McCarty, Andras Gruber, Anton Matafonov, David Gailani
Thromb Haemost. Author manuscript; available in PMC 2018 Apr 3.
Published in final edited form as: Thromb Haemost. 2017 Apr 3; 117(4): 671–681. Published online 2017 Jan 26. doi: 10.1160/TH16-09-0691
PMCID:
PMC5696789
AbstractArticlePDF–976K
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system
Nilima Biswas, Adam X. Maihofer, Saiful Anam Mir, Fangwen Rao, Kuixing Zhang, Srikrishna Khandrika, Manjula Mahata, Ryan S. Friese, C. Makena Hightower, Sushil K. Mahata, Dewleen G. Baker, Caroline M. Nievergelt, Sucheta M. Vaingankar, Daniel T. O’Connor
BMC Med Genet. 2016; 17: 21. Published online 2016 Mar 11. doi: 10.1186/s12881-016-0283-5
PMCID:
PMC4788869
AbstractArticlePDF–3.3M
11.
Plasma prekallikrein levels are positively associated with circulating lipid levels and the metabolic syndrome in children
James A. MacKenzie, Kristen A. Roosa, Brooks B. Gump, Amy K. Dumas, Kestutis G. Bendinskas
Appl Physiol Nutr Metab. Author manuscript; available in PMC 2015 Sep 28.
Published in final edited form as: Appl Physiol Nutr Metab. 2010 Aug; 35(4): 518–525. doi: 10.1139/H10-039
PMCID:
PMC4586083
AbstractArticlePDF–247K
12.
Prolylcarboxypeptidase Independently Activates Plasma Prekallikrein (Fletcher Factor)
J. Wang, A. Matafonov, H. Madkhali, F. Mahdi, D. Watson, A.H. Schmaier, D. Gailani, Z. Shariat-Madar
Curr Mol Med. Author manuscript; available in PMC 2015 Mar 23.
Published in final edited form as: Curr Mol Med. 2014; 14(9): 1173–1185. doi: 10.2174/1566524014666141015153519
PMCID:
PMC4369925
AbstractArticlePDF–2.7M
13.
Genome-Wide Meta-Analyses of Plasma Renin Activity and Concentration Reveal Association with the Kininogen 1 and Prekallikrein Genes
Wolfgang Lieb, Ming-Huei Chen, Alexander Teumer, Rudolf A. de Boer, Honghuang Lin, Ervin R. Fox, Solomon K. Musani, James G. Wilson, Thomas J. Wang, Henry Völzke, Ann-Kristin Petersen, Christine Meisinger, Matthias Nauck, Sabrina Schlesinger, Yong Li, Jöel Menard, Serge Hercberg, H.-Erich Wichmann, Uwe Völker, Rajesh Rawal, Martin Bidlingmaier, Anke Hannemann, Marcus Dörr, Rainer Rettig, Wiek H. van Gilst, Dirk J. van Veldhuisen, Stephan J.L. Bakker, Gerjan Navis, Henri Wallaschofski, Pierre Meneton, Pim van der Harst, Martin Reincke, Ramachandran S. Vasan, CKDGen Consortium, CKDGen Consortium, ICBP, EchoGen Consortium
Circ Cardiovasc Genet. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Circ Cardiovasc Genet. 2015 Feb; 8(1): 131–140. Published online 2014 Dec 4. doi: 10.1161/CIRCGENETICS.114.000613
PMCID:
PMC4354880
AbstractArticlePDF–574K
14.
An atlas of genetic influences on human blood metabolites
So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo
Nat Genet. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982
PMCID:
PMC4064254
AbstractArticlePDF–2.4M
15.
Genetic Determinants Influencing Human Serum Metabolome among African Americans
Bing Yu, Yan Zheng, Danny Alexander, Alanna C. Morrison, Josef Coresh, Eric Boerwinkle
PLoS Genet. 2014 Mar; 10(3): e1004212. Published online 2014 Mar 13. doi: 10.1371/journal.pgen.1004212
PMCID:
PMC3952826
AbstractArticlePDF–794K
16.
Human metabolic individuality in biomedical and pharmaceutical research
Karsten Suhre, So-Youn Shin, Ann-Kristin Petersen, Robert P. Mohney, David Meredith, Brigitte Wägele, Elisabeth Altmaier, CARDIoGRAM, Panos Deloukas, Jeanette Erdmann, Elin Grundberg, Christopher J. Hammond, Martin Hrabé de Angelis, Gabi Kastenmüller, Anna Köttgen, Florian Kronenberg, Massimo Mangino, Christa Meisinger, Thomas Meitinger, Hans-Werner Mewes, Michael V. Milburn, Cornelia Prehn, Johannes Raffler, Janina S. Ried, Werner Römisch-Margl, Nilesh J. Samani, Kerrin S. Small, H.-Erich Wichmann, Guangju Zhai, Thomas Illig, Tim D. Spector, Jerzy Adamski, Nicole Soranzo, Christian Gieger
Nature. Author manuscript; available in PMC 2013 Nov 19.
Published in final edited form as: Nature. 2011 Aug 31; 477(7362): 10.1038/nature10354. Published online 2011 Aug 31. doi: 10.1038/nature10354
PMCID:
PMC3832838
AbstractArticlePDF–839K
17.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
AbstractArticlePDF–630K
18.
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
Johannes Kettunen, Taru Tukiainen, Antti-Pekka Sarin, Alfredo Ortega-Alonso, Emmi Tikkanen, Leo-Pekka Lyytikäinen, Antti J Kangas, Pasi Soininen, Peter Würtz, Kaisa Silander, Danielle M Dick, Richard J Rose, Markku J Savolainen, Jorma Viikari, Mika Kähönen, Terho Lehtimäki, Kirsi H Pietiläinen, Michael Inouye, Mark I McCarthy, Antti Jula, Johan Eriksson, Olli T Raitakari, Veikko Salomaa, Jaakko Kaprio, Marjo-Riitta Järvelin, Leena Peltonen, Markus Perola, Nelson B Freimer, Mika Ala-Korpela, Aarno Palotie, Samuli Ripatti
Nat Genet. Author manuscript; available in PMC 2013 Mar 21.
Published in final edited form as: Nat Genet. 2012 Jan 29; 44(3): 269–276. Published online 2012 Jan 29. doi: 10.1038/ng.1073
PMCID:
PMC3605033
AbstractArticlePDF–1.8M
19.
Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte
PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954
PMCID:
PMC3522587
AbstractArticlePDF–130K
20.
Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis
Michael Inouye, Samuli Ripatti, Johannes Kettunen, Leo-Pekka Lyytikäinen, Niku Oksala, Pirkka-Pekka Laurila, Antti J. Kangas, Pasi Soininen, Markku J. Savolainen, Jorma Viikari, Mika Kähönen, Markus Perola, Veikko Salomaa, Olli Raitakari, Terho Lehtimäki, Marja-Riitta Taskinen, Marjo-Riitta Järvelin, Mika Ala-Korpela, Aarno Palotie, Paul I. W. de Bakker
PLoS Genet. 2012 Aug; 8(8): e1002907. Published online 2012 Aug 16. doi: 10.1371/journal.pgen.1002907
PMCID:
PMC3420921
AbstractArticlePDF–919K

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