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Select item 106415241.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 97460062.

SCARA5 induced ferroptosis to effect ESCC proliferation and metastasis by combining with Ferritin light chain

Yanqun Liu, Rong Xiong, Ting Xiao, Li Xiong, Jialin Wu, Junfeng Li, Gang Feng, Guiqin Song, Kang Liu

BMC Cancer. 2022; 22: 1304. Published online 2022 Dec 13. doi: 10.1186/s12885-022-10414-9

PMCID:: PMC9746006

Abstract Article PDF–9.6M

Select item 92323223.

Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma

Kawuli Jumai, Tangjuan Zhang, Bingzhang Qiao, Julaiti Ainiwaer, Haiping Zhang, Zhichao Hou, Idris Awut, Madinyat Niyaz, Liwei Zhang, Ilyar Sheyhidin

J Immunol Res. 2022; 2022: 2555647. Published online 2022 Jun 17. doi: 10.1155/2022/2555647

PMCID:: PMC9232322

Abstract Article PDF–3.5M

Select item 84291724.

Tumor suppressive effect of scavenger receptor class A member 5 overexpression in colorectal cancer by regulating PI3K/AKT/mTOR pathway

Yi Li, Feng Peng, Xiangyun Tan, Jin Wang, Yeqing Xu

Genes Genomics. 2021; 43(10): 1189–1198. Published online 2021 Aug 21. doi: 10.1007/s13258-021-01139-3

PMCID:: PMC8429172

Abstract Article PDF–7.2M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78212256.

SCARA5 suppresses the proliferation and migration, and promotes the apoptosis of human retinoblastoma cells by inhibiting the PI3K/AKT pathway

Jinwei Wang, Sha Wang, Lu Chen, Jia Tan

Mol Med Rep. 2021 Mar; 23(3): 202. Published online 2021 Jan 13. doi: 10.3892/mmr.2021.11841

PMCID:: PMC7821225

Abstract Article PDF–915K

Select item 76679617.

Interactions of ferritin with scavenger receptor class A members

Bowen Yu, Chen Cheng, Yichun Wu, Luqiang Guo, Dandan Kong, Ze Zhang, Yuanyuan Wang, Enlin Zheng, Yingbin Liu, Yongning He

J Biol Chem. 2020 Nov 13; 295(46): 15727–15741. Published online 2020 Sep 9. doi: 10.1074/jbc.RA120.014690

PMCID:: PMC7667961

Abstract Article PDF–4.6M

Select item 76571798.

Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan

Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura

Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186

PMCID:: PMC7657179

Abstract Article PDF–225K

Select item 73924919.

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

Ann Rheum Dis. 2020 Aug; 79(8): 1111–1120. Published online 2020 May 14. doi: 10.1136/annrheumdis-2019-216911

PMCID:: PMC7392491

Abstract Article PDF–14M

Select item 721691110.

Scavenger receptor class A, member 5 is associated with thyroid cancer cell lines progression via epithelial‐mesenchymal transition

Chen Zheng, Er‐Jie Xia, Rui‐Da Quan, Adheesh Bhandari, Ou‐Chen Wang, Ru‐Tian Hao

Cell Biochem Funct. 2020 Mar; 38(2): 158–166. Published online 2020 Jan 27. doi: 10.1002/cbf.3455

PMCID:: PMC7216911

Abstract Article PDF–4.3M

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 668915112.

The scavenger receptor SCARA5 is an endocytic receptor for von Willebrand factor expressed by littoral cells in the human spleen

Laura L. Swystun, Kenichi Ogiwara, Jesse D. Lai, Juha R. M. Ojala, Orla Rawley, Fanny Lassalle, Colleen Notley, Olle Rengby, Alison Michels, Kate Nesbitt, Karl Tryggvason, David Lillicrap

J Thromb Haemost. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: J Thromb Haemost. 2019 Aug; 17(8): 1384–1396. Published online 2019 Jun 20. doi: 10.1111/jth.14521

PMCID:: PMC6689151

Abstract Article PDF–2.7M

Select item 615442313.

SPAG5 promotes hepatocellular carcinoma progression by downregulating SCARA5 through modifying β-catenin degradation

Hongliang Liu, Junwen Hu, Ran Wei, Longfei Zhou, Hua Pan, Hongchao Zhu, Mingwen Huang, Jun Luo, Wei Xu

J Exp Clin Cancer Res. 2018; 37: 229. Published online 2018 Sep 18. doi: 10.1186/s13046-018-0891-3

PMCID:: PMC6154423

Abstract Article PDF–3.4M

Select item 566232314.

Methylation analysis of p16, SLIT2, SCARA5, and Runx3 genes in hepatocellular carcinoma

Gaofeng Sun, Chen Zhang, Min Feng, Wensheng Liu, Huifang Xie, Qin Qin, E. Zhao, Li Wan

Medicine (Baltimore) 2017 Oct; 96(41): e8279. Published online 2017 Oct 13. doi: 10.1097/MD.0000000000008279

PMCID:: PMC5662323

Abstract Article PDF–335K

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 526093916.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 462790317.

SCARA5 and Suprabasin are Hub Genes of Co-expression Network Modules Associated with Peripheral Vein Graft Patency

Richard D Kenagy, M Civelek, Shinsuke Kikuchi, Lihua Chen, A Grieff, Michael Sobel, Aldons J Lusis, Alexander W Clowes

J Vasc Surg. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: J Vasc Surg. 2016 Jul; 64(1): 202–209.e6. Published online 2015 Apr 30. doi: 10.1016/j.jvs.2014.12.052

PMCID:: PMC4627903

Abstract Article PDF–245K

Select item 417802418.

L-Ferritin Binding to Scara5: A New Iron Traffic Pathway Potentially Implicated in Retinopathy

Luísa Mendes-Jorge, David Ramos, Andreia Valença, Mariana López-Luppo, Virgínia Maria Rico Pires, Joana Catita, Victor Nacher, Marc Navarro, Ana Carretero, Alfonso Rodriguez-Baeza, Jesús Ruberte

PLoS One. 2014; 9(9): e106974. Published online 2014 Sep 26. doi: 10.1371/journal.pone.0106974

Correction in:: PLoS One. 2017; 12(6): e0180288.

PMCID:: PMC4178024

Abstract Article PDF–2.8M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316351420.

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels

Guillemette Antoni, Tiphaine Oudot-Mellakh, Apostolos Dimitromanolakis, Marine Germain, William Cohen, Philip Wells, Mark Lathrop, France Gagnon, Pierre-Emmanuel Morange, David-Alexandre Tregouet

BMC Med Genet. 2011; 12: 102. Published online 2011 Aug 2. doi: 10.1186/1471-2350-12-102

PMCID:: PMC3163514

Abstract Article PDF–303K

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