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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 97425392.

AKR1B8 deficiency drives severe DSS-induced acute colitis through invasion of luminal bacteria and activation of innate immunity

Qiulin Deng, Yichen Yao, Jing Yang, Ramina Khoshaba, Yi Shen, Xin Wang, Deliang Cao

Front Immunol. 2022; 13: 1042549. Published online 2022 Nov 28. doi: 10.3389/fimmu.2022.1042549

PMCID:: PMC9742539

Abstract Article PDF–5.7M

Select item 79908593.

Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain

Ivelisse Cajigas, Abhijit Chakraborty, Madison Lynam, Kelsey R. Swyter, Monique Bastidas, Linden Collens, Hao Luo, Ferhat Ay, Jhumku D. Kohtz

Development. 2021 Mar 15; 148(6): dev197202. Published online 2021 Mar 15. doi: 10.1242/dev.197202

PMCID:: PMC7990859

Abstract Article

Select item 79074354.

Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice

Xin Wang, Ramina Khoshaba, Yi Shen, Yu Cao, Minglin Lin, Yun Zhu, Zhe Cao, Duan-Fang Liao, Deliang Cao

Front Cell Dev Biol. 2021; 9: 632805. Published online 2021 Feb 12. doi: 10.3389/fcell.2021.632805

PMCID:: PMC7907435

Abstract Article PDF–3.8M

Select item 69433545.

Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis

Yongzhen Liu, Jing Zhang, Hui Liu, Guiwen Guan, Ting Zhang, Leijie Wang, Xuewei Qi, Huiling Zheng, Chia-Chen Chen, Jia Liu, Deliang Cao, Fengmin Lu, Xiangmei Chen

Am J Cancer Res. 2019; 9(12): 2730–2748. Published online 2019 Dec 1.

PMCID:: PMC6943354

Abstract Article PDF–6.9M

Select item 64280506.

The Evf2 ultraconserved enhancer lncRNA functionally and spatially organizes multi-megabase distant genes in developing forebrain

Ivelisse Cajigas, Abhijit Chakraborty, Kelsey R. Swyter, Hao Luo, Monique Bastidas, Maximilliano Nigro, Elizabeth R. Morris, Sean Chen, Michael J. W. VanGompel, David Leib, Sara J. Kohtz, Marco Martina, Sooky Koh, Ferhat Ay, Jhumku D. Kohtz

Mol Cell. Author manuscript; available in PMC 2019 Sep 20.

Published in final edited form as: Mol Cell. 2018 Sep 20; 71(6): 956–972.e9. Published online 2018 Aug 23. doi: 10.1016/j.molcel.2018.07.024

PMCID:: PMC6428050

Abstract Article PDF–2.0M

Select item 55032617.

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program

John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt

PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682

PMCID:: PMC5503261

Abstract Article PDF–31M

Select item 53376188.

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla

Dev Cell. 2017 Feb 27; 40(4): 331–341.e4. doi: 10.1016/j.devcel.2017.01.015

PMCID:: PMC5337618

Abstract Article

Select item 52958219.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 435996510.

Impaired Self-Renewal and Increased Colitis and Dysplastic Lesions in Colonic Mucosa of AKR1B8 Deficient Mice

Yi Shen, Jun Ma, Ruilan Yan, Hongyan Ling, Xiaoning Li, Wancai Yang, John Gao, Chenfei Huang, Yiwen Bu, Yu Cao, Yingchun He, Laxiang Wan, Xuyu Zu, Jianghua Liu, Mei Chris Huang, William F Stenson, Duan-Fang Liao, Deliang Cao

Clin Cancer Res. Author manuscript; available in PMC 2016 Mar 15.

Published in final edited form as: Clin Cancer Res. 2015 Mar 15; 21(6): 1466–1476. Published online 2014 Dec 23. doi: 10.1158/1078-0432.CCR-14-2072

PMCID:: PMC4359965

Abstract Article PDF–3.0M

Select item 412899011.

Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway

Zhenwang Tang, Chenglai Xia, Renbin Huang, Xiaoning Li, Wan-Chun Wang, Wangyuan Guo, Lili Duan, Weihao Luo, Deliang Cao, Di-Xian Luo

Int J Clin Exp Pathol. 2014; 7(7): 3791–3799. Published online 2014 Jun 15.

PMCID:: PMC4128990

Abstract Article PDF–1023K

Select item 396495512.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253414.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 300186415.

Identification of Genes and Networks Driving Cardiovascular and Metabolic Phenotypes in a Mouse F2 Intercross

Jonathan M. J. Derry, Hua Zhong, Cliona Molony, Doug MacNeil, Debraj Guhathakurta, Bin Zhang, John Mudgett, Kersten Small, Lahcen El Fertak, Alain Guimond, Mohammed Selloum, Wenqing Zhao, Marie France Champy, Laurent Monassier, Tom Vogt, Doris Cully, Andrew Kasarskis, Eric E. Schadt

PLoS One. 2010; 5(12): e14319. Published online 2010 Dec 14. doi: 10.1371/journal.pone.0014319

PMCID:: PMC3001864

Abstract Article PDF–443K

Select item 192515416.

Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Matthew Spite, Shahid P. Baba, Yonis Ahmed, Oleg A. Barski, Kanchan Nijhawan, J. Mark Petrash, Aruni Bhatnagar, Sanjay Srivastava

Biochem J. 2007 Jul 1; 405(Pt 1): 95–105. Prepublished online 2007 Mar 23. Published online 2007 Jun 13. doi: 10.1042/BJ20061743

PMCID:: PMC1925154

Abstract Article PDF–201K

Select item 141356817.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086