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Items: 1 to 20 of 63

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López-Tello, Brian Y.H. Lam, Samira N. Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, Cristina M. Branco, Amanda N. Sferruzzi-Perri, Miguel Constância
Dev Cell. 2022 Jan 10; 57(1): 63–79.e8. doi: 10.1016/j.devcel.2021.12.005
PMCID:
PMC8751640
AbstractArticle
3.
Liver specific deletion of mouse Tm6sf2 promotes steatosis, fibrosis and hepatocellular cancer
Elizabeth P. Newberry, Zoe Hall, Yan Xie, Elizabeth A. Molitor, Peter O. Bayguinov, Gregory W. Strout, James A.J. Fitzpatrick, Elizabeth M. Brunt, Julian L. Griffin, Nicholas O. Davidson
Hepatology. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Hepatology. 2021 Sep; 74(3): 1203–1219. Published online 2021 May 22. doi: 10.1002/hep.31771
PMCID:
PMC8390580
AbstractArticlePDF–3.5M
4.
Epac1 upregulates LOX-1 to promote foam cell formation and atherosclerosis development
William G. Robichaux, III, Fang C. Mei, Wenli Yang, Hui Wang, Hua Sun, Zhen Zhou, Dianna M. Milewicz, Ba-Bie Teng, Xiaodong Cheng
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 Dec; 40(12): e322–e335. Published online 2020 Oct 15. doi: 10.1161/ATVBAHA.119.314238
PMCID:
PMC7831851
AbstractArticlePDF–1.2M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA
Vincent Caval, Wenjuan Jiao, Noémie Berry, Pierre Khalfi, Emmanuelle Pitré, Valérie Thiers, Jean-Pierre Vartanian, Simon Wain-Hobson, Rodolphe Suspène
BMC Genomics. 2019; 20: 858. Published online 2019 Nov 14. doi: 10.1186/s12864-019-6216-x
PMCID:
PMC6854741
AbstractArticlePDF–2.0M
7.
Comparison of RNA editing activity of APOBEC1-A1CF and APOBEC1-RBM47 complexes reconstituted in HEK293T cells
Aaron D. Wolfe, Don B. Arnold, Xiaojiang Chen
J Mol Biol. Author manuscript; available in PMC 2020 Mar 29.
Published in final edited form as: J Mol Biol. 2019 Mar 29; 431(7): 1506–1517. Published online 2019 Mar 4. doi: 10.1016/j.jmb.2019.02.025
PMCID:
PMC6443457
AbstractArticlePDF–1.0M
8.
Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoproteins
Yu-Xin Xu, Valeska Redon, Haojie Yu, William Querbes, James Pirruccello, Abigail Liebow, Amy Deik, Kevin Trindade, Xiao Wang, Kiran Musunuru, Clary B. Clish, Chad Cowan, Kevin Fizgerald, Daniel Rader, Sekar Kathiresan
Atherosclerosis. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Atherosclerosis. 2018 Jan; 268: 196–206. Published online 2017 Sep 21. doi: 10.1016/j.atherosclerosis.2017.08.031
PMCID:
PMC5750127
AbstractArticlePDF–2.3M
9.
Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology
Daniel C. Cole, Youngcheul Chung, Khatuna Gagnidze, Kaitlyn H. Hajdarovic, Violeta Rayon-Estrada, Dewi Harjanto, Benedetta Bigio, Judit Gal-Toth, Teresa A. Milner, Bruce S. McEwen, F. Nina Papavasiliou, Karen Bulloch
Proc Natl Acad Sci U S A. 2017 Dec 12; 114(50): 13272–13277. Published online 2017 Nov 22. doi: 10.1073/pnas.1710493114
PMCID:
PMC5740644
AbstractArticlePDF–1.1M
10.
A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels
Sumeet A Khetarpal, Xuemei Zeng, John S Millar, Cecilia Vitali, Amritha Varshini Hanasoge Somasundara, Paolo Zanoni, James A Landro, Nicole Barucci, William J Zavadoski, Zhiyuan Sun, Hans de Haard, Ildikó V Toth, Gina M Peloso, Pradeep Natarajan, Marina Cuchel, Sissel Lund-Katz, Michael C Phillips, Alan R Tall, Sekar Kathiresan, Paul DaSilva-Jardine, Nathan A Yates, Daniel J Rader
Nat Med. Author manuscript; available in PMC 2017 Nov 3.
Published in final edited form as: Nat Med. 2017 Sep; 23(9): 1086–1094. Published online 2017 Aug 21. doi: 10.1038/nm.4390
PMCID:
PMC5669375
AbstractArticlePDF–1.0M
11.
Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization
Joseph H. Nadeau
Genetics. 2017 Oct; 207(2): 369–387. Published online 2017 Sep 29. doi: 10.1534/genetics.117.300109
PMCID:
PMC5629312
AbstractArticlePDF–957K
12.
APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo
Elizabeth M. Snyder, Christopher McCarty, Adrienne Mehalow, Karen L. Svenson, Stephen A. Murray, Ron Korstanje, Robert E. Braun
RNA. 2017 Apr; 23(4): 457–465. doi: 10.1261/rna.058818.116
PMCID:
PMC5340909
AbstractArticlePDF–848K
13.
Absence of Hyperlipidemia in LDL Receptor–Deficient Mice Having Apolipoprotein B100 Without the Putative Receptor-Binding Sequences
Lance A. Johnson, Michael K. Altenburg, Rosemary L. Walzem, Lori T. Scanga, Nobuyo Maeda
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jan 26.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Oct; 28(10): 1745–1752. Published online 2008 Jul 10. doi: 10.1161/ATVBAHA.108.169680
PMCID:
PMC5268125
AbstractArticlePDF–919K
14.
Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models
Syuji Kurogi, Tomohisa Sekimoto, Taro Funamoto, Tomomi Ota, Shihoko Nakamura, Takuya Nagai, Mai Nakahara, Kumiko Yoshinobu, Kimi Araki, Masatake Araki, Etsuo Chosa
Sci Rep. 2017; 7: 40692. Published online 2017 Jan 20. doi: 10.1038/srep40692
PMCID:
PMC5247747
AbstractArticlePDF–1.9M
15.
Chromosomal mapping of the αMHC-MerCreMer transgene in mice reveals a large genomic deletion
Stephanie Harkins, J. Lindsay Whitton
Transgenic Res. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Transgenic Res. 2016 Oct; 25(5): 639–648. Published online 2016 May 10. doi: 10.1007/s11248-016-9960-6
PMCID:
PMC5105329
AbstractArticlePDF–675K
16.
Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis
Donna M. Conlon, Tiffany Thomas, Tatyana Fedotova, Antonio Hernandez-Ono, Gilbert Di Paolo, Robin B. Chan, Kelly Ruggles, Sarah Gibeley, Jing Liu, Henry N. Ginsberg
J Clin Invest. 2016 Oct 3; 126(10): 3852–3867. Published online 2016 Sep 6. doi: 10.1172/JCI86028
PMCID:
PMC5096813
AbstractArticlePDF–4.7M
17.
Parent-of-origin effects of A1CF and AGO2 on testicular germ-cell tumors, testicular abnormalities, and fertilization bias
Delphine Carouge, Valerie Blanc, Sue E. Knoblaugh, Robert J. Hunter, Nicholas O. Davidson, Joseph H. Nadeau
Proc Natl Acad Sci U S A. 2016 Sep 13; 113(37): E5425–E5433. Published online 2016 Aug 31. doi: 10.1073/pnas.1604773113
PMCID:
PMC5027451
AbstractArticlePDF–975K
18.
Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy
Dongxu Fu, Jeremy Y. Yu, Shihe Yang, Mingyuan Wu, Samar M. Hammad, Anna R. Connell, Mei Du, Junping Chen, Timothy J. Lyons
Diabetologia. 2016; 59(10): 2251–2261. Published online 2016 Jul 30. doi: 10.1007/s00125-016-4058-5
PMCID:
PMC5016562
AbstractArticlePDF–1.0M
19.
Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans
Gissette Reyes-Soffer, Byoung Moon, Antonio Hernandez-Ono, Marija Dionizovik-Dimanovski, Jhonsua Jimenez, Joseph Obunike, Tiffany Thomas, Colleen Ngai, Nelson Fontanez, Daniel S. Donovan, Wahida Karmally, Stephen Holleran, Rajasekhar Ramakrishnan, Robert S. Mittleman, Henry N. Ginsberg
Sci Transl Med. Author manuscript; available in PMC 2016 Jul 14.
Published in final edited form as: Sci Transl Med. 2016 Jan 27; 8(323): 323ra12. doi: 10.1126/scitranslmed.aad2195
Correction in:
Sci Transl Med. 2016 Feb 10; 8(325): 325er3.
PMCID:
PMC4944115
AbstractArticlePDF–653K
20.
Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterol
Salam Ibrahim, Suryanarayan Somanathan, Jeffrey Billheimer, James M. Wilson, Daniel J. Rader
Cardiovasc Res. 2016 May 1; 110(1): 23–29. Published online 2016 Jan 19. doi: 10.1093/cvr/cvw010
PMCID:
PMC4798044
AbstractArticlePDF–582K

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