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Select item 112977041.

Prion protein gene (PRNP) variation in German and Danish cervids

Sonja Ernst, Agata Piestrzyńska-Kajtoch, Jörn Gethmann, Małgorzata Natonek-Wiśniewska, Balal Sadeghi, Miroslaw P. Polak, Markus Keller, Dolores Gavier-Widén, Katayoun Moazami-Goudarzi, Fiona Houston, Martin H. Groschup, Christine Fast

Vet Res. 2024; 55: 98. Published online 2024 Aug 2. doi: 10.1186/s13567-024-01340-8

PMCID:: PMC11297704

Abstract Article PDF–4.1M

Select item 111461582.

Structural features of prions explored by sequence analysis. II. A PrP^Sc model

J.-P. Mornon, K. Prat, F. Dupuis, N. Boisset, I. Callebaut

Cell Mol Life Sci. 2002 Dec; 59(12): 2144–2154. doi: 10.1007/s000180200014

PMCID:: PMC11146158

Abstract Article PDF–623K

Select item 111314583.

The role of P-glycoprotein/cellular prion protein interaction in multidrug-resistant breast cancer cells treated with paclitaxel

Q.-Q. Li, X.-X. Cao, J.-D. Xu, Q. Chen, W.-J. Wang, F. Tang, Z.-Q. Chen, X.-P. Liu, Z.-D. Xu

Cell Mol Life Sci. 2009 Feb; 66(3): 504. Published online 2008 Dec 19. doi: 10.1007/s00018-008-8548-6

PMCID:: PMC11131458

Abstract Article PDF–3.7M

Select item 111147714.

Functional mechanisms of the cellular prion protein (PrP^C) associated anti-HIV-1 properties

Sandrine Alais, Ricardo Soto-Rifo, Vincent Balter, Henri Gruffat, Evelyne Manet, Laurent Schaeffer, Jean Luc Darlix, Andrea Cimarelli, Graça Raposo, Théophile Ohlmann, Pascal Leblanc

Cell Mol Life Sci. 2012 Apr; 69(8): 1331–1352. Published online 2011 Nov 11. doi: 10.1007/s00018-011-0879-z

PMCID:: PMC11114771

Abstract Article PDF–1.4M

Select item 110731705.

Cellular prion protein dysfunction in a prototypical inherited metabolic myopathy

Fatima-Zohra Boufroura, Céline Tomkiewicz-Raulet, Virginie Poindessous, Johan Castille, Jean-Luc Vilotte, Jean Bastin, Sophie Mouillet-Richard, Fatima Djouadi

Cell Mol Life Sci. 2021 Mar; 78(5): 2157–2167. Published online 2020 Sep 1. doi: 10.1007/s00018-020-03624-6

PMCID:: PMC11073170

Abstract Article PDF–8.4M

Select item 109321756.

New Light on Prions: Putative Role of PrP^c in Pathophysiology of Mood Disorders

Adrian Andrzej Chrobak, Patrycja Pańczyszyn-Trzewik, Patrycja Król, Magdalena Pawelec-Bąk, Dominika Dudek, Marcin Siwek

Int J Mol Sci. 2024 Mar; 25(5): 2967. Published online 2024 Mar 4. doi: 10.3390/ijms25052967

PMCID:: PMC10932175

Abstract Article PDF–382K

Select item 108631477.

Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas

Jacqueline Marcia Boccacino, Rafael dos Santos Peixoto, Camila Felix de Lima Fernandes, Giovanni Cangiano, Paula Rodrigues Sola, Bárbara Paranhos Coelho, Mariana Brandão Prado, Maria Isabel Melo-Escobar, Breno Pereira de Sousa, Shamini Ayyadhury, Gary D. Bader, Sueli Mieko Oba Shinjo, Suely Kazue Nagahashi Marie, Edroaldo Lummertz da Rocha, Marilene Hohmuth Lopes

BMC Cancer. 2024; 24: 199. Published online 2024 Feb 13. doi: 10.1186/s12885-024-11914-6

PMCID:: PMC10863147

Abstract Article PDF–5.2M

Select item 107999038.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 107093759.

Excess PrP^C inhibits muscle cell differentiation via miRNA-enhanced liquid–liquid phase separation implicated in myopathy

Jing Tao, Yanping Zeng, Bin Dai, Yin Liu, Xiaohan Pan, Li-Qiang Wang, Jie Chen, Yu Zhou, Zuneng Lu, Liwei Xie, Yi Liang

Nat Commun. 2023; 14: 8131. Published online 2023 Dec 8. doi: 10.1038/s41467-023-43826-7

PMCID:: PMC10709375

Abstract Article PDF–6.1M

Select item 1057353410.

Elevated E200K Somatic Mutation of the Prion Protein Gene (PRNP) in the Brain Tissues of Patients with Sporadic Creutzfeldt–Jakob Disease (CJD)

Sae-Young Won, Yong-Chan Kim, Byung-Hoon Jeong

Int J Mol Sci. 2023 Oct; 24(19): 14831. Published online 2023 Oct 2. doi: 10.3390/ijms241914831

PMCID:: PMC10573534

Abstract Article PDF–1.4M

Select item 1039973811.

Copper homeostasis-associated gene PRNP regulates ferroptosis and immune infiltration in breast cancer

Changwei Lin, Jiaqing He, Xiaopei Tong, Liying Song

PLoS One. 2023; 18(8): e0288091. Published online 2023 Aug 3. doi: 10.1371/journal.pone.0288091

PMCID:: PMC10399738

Abstract Article PDF–3.6M

Select item 1023742212.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1016646313.

A novel subtype of sporadic Creutzfeldt–Jakob disease with PRNP codon 129MM genotype and PrP plaques

Rabeah Bayazid, Christina Orru’, Rabail Aslam, Yvonne Cohen, Amelia Silva-Rohwer, Seong-Ki Lee, Rossana Occhipinti, Qingzhong Kong, Shashirekha Shetty, Mark L. Cohen, Byron Caughey, Lawrence B. Schonberger, Brian S. Appleby, Ignazio Cali

Acta Neuropathol. 2023; 146(1): 121–143. Published online 2023 May 8. doi: 10.1007/s00401-023-02581-1

Correction in:: Acta Neuropathol. 2023; 146(1): 167–170.

PMCID:: PMC10166463

Abstract Article PDF–4.3M

Select item 1010924914.

PRNP expression predicts imaging findings in sporadic Creutzfeldt‐Jakob disease

Iris J. Broce, Eduardo Caverzasi, Simone Sacco, Ryan Michael Nillo, Matteo Paoletti, Rahul S. Desikan, Michael Geschwind, Leo P. Sugrue

Ann Clin Transl Neurol. 2023 Apr; 10(4): 536–552. Published online 2023 Feb 6. doi: 10.1002/acn3.51739

PMCID:: PMC10109249

Abstract Article PDF–3.4M

Select item 973704515.

Systematic Review of Clinical and Pathophysiological Features of Genetic Creutzfeldt–Jakob Disease Caused by a Val-to-Ile Mutation at Codon 180 in the Prion Protein Gene

Taiki Matsubayashi, Nobuo Sanjo

Int J Mol Sci. 2022 Dec; 23(23): 15172. Published online 2022 Dec 2. doi: 10.3390/ijms232315172

PMCID:: PMC9737045

Abstract Article PDF–1.5M

Select item 953700716.

Downregulated PRNP Facilitates Cell Proliferation and Invasion and Has Effect on the Immune Regulation in Ovarian Cancer

Kuan Hu, Xiaofang Zhang, Lei Zhou, Juanni Li

J Immunol Res. 2022; 2022: 3205040. Published online 2022 Sep 29. doi: 10.1155/2022/3205040

PMCID:: PMC9537007

Abstract Article PDF–2.7M

Select item 951327917.

Met/Val129 polymorphism of the full-length human prion protein dictates distinct pathways of amyloid formation

Thomas Pauly, Najoua Bolakhrif, Jesko Kaiser, Luitgard Nagel-Steger, Lothar Gremer, Holger Gohlke, Dieter Willbold

J Biol Chem. 2022 Oct; 298(10): 102430. Published online 2022 Aug 28. doi: 10.1016/j.jbc.2022.102430

PMCID:: PMC9513279

Abstract Article PDF–1.4M

Select item 950006718.

Hereditary E200K mutation within the prion protein gene alters human iPSC derived cardiomyocyte function

Aleksandar R. Wood, Simote T. Foliaki, Bradley R. Groveman, Ryan O. Walters, Katie Williams, Jue Yuan, Wen-Quan Zou, Cathryn L. Haigh

Sci Rep. 2022; 12: 15788. Published online 2022 Sep 22. doi: 10.1038/s41598-022-19631-5

PMCID:: PMC9500067

Abstract Article PDF–7.5M

Select item 946420619.

Characteristic distribution and molecular properties of normal cellular prion protein in human endocrine and exocrine tissues

Sachiko Koyama, Hideko Noguchi, Kaoru Yagita, Hideomi Hamasaki, Masahiro Shijo, Motoi Yoshimura, Kohei Inoshita, Naokazu Sasagasako, Hiroyuki Honda

Sci Rep. 2022; 12: 15289. Published online 2022 Sep 10. doi: 10.1038/s41598-022-19632-4

PMCID:: PMC9464206

Abstract Article PDF–2.3M

Select item 923162320.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

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