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Items: 1 to 20 of 73

1.
Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases
Pavel Dundr, Alba Machado-Lopez, Aymara Mas, Zuzana Věcková, Michal Mára, Adéla Richtárová, Radoslav Matěj, Ivana Stružinská, Michaela Kendall Bártů, Kristýna Němejcová, Jiří Dvořák, Jan Hojný
Virchows Arch. 2024; 484(6): 1015–1022. Published online 2023 Jul 19. doi: 10.1007/s00428-023-03603-9
PMCID:
PMC11186871
AbstractArticlePDF–1.6M
2.
Structural insights into BCDX2 complex function in homologous recombination
Yashpal Rawal, Lijia Jia, Aviv Meir, Shuo Zhou, Hardeep Kaur, Eliza A. Ruben, Youngho Kwon, Kara A. Bernstein, Maria Jasin, Alexander B. Taylor, Sandeep Burma, Robert Hromas, Alexander V. Mazin, Weixing Zhao, Daohong Zhou, Elizabeth V. Wasmuth, Eric C. Greene, Patrick Sung, Shaun K. Olsen
Nature. Author manuscript; available in PMC 2024 Jul 1.
Published in final edited form as: Nature. 2023 Jul; 619(7970): 640–649. Published online 2023 Jun 21. doi: 10.1038/s41586-023-06219-w
PMCID:
PMC10712684
AbstractArticlePDF–9.7M
3.
RAD51B Harbors Germline Mutations Associated With Pancreatic Ductal Adenocarcinoma
Fanfan Xie, Ding Ding, Cong Lin, Dea Cunningham, Michael Wright, Ammar A. Javed, Nilo Azad, Valerie Lee, Ross Donehower, Ana De Jesus-Acosta, Dung T. Le, Michael Pishvaian, Eun Ji Shin, Anne Marie Lennon, Mouen Khashab, Vikesh Singh, Alison P. Klein, Nicholas J. Roberts, Amy Hacker-Prietz, Thomas McPhaul, Richard A. Burkhart, William R. Burns, Amol Narang, Atif Zaheer, Elliot K. Fishman, Elizabeth D. Thompson, Robert Anders, Jun Yu, Jin He, Christopher L. Wolfgang, Lei Zheng, Dongbing Liu, Kui Wu, Daniel A. Laheru
JCO Precis Oncol. 2022; 6: e2100404. Published online 2022 Jun 23. doi: 10.1200/PO.21.00404
PMCID:
PMC9848593
AbstractArticlePDF–270K
4.
A protein interaction landscape of breast cancer
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
Science. Author manuscript; available in PMC 2022 Apr 26.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
PMCID:
PMC9040556
AbstractArticlePDF–2.2M
5.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
8.
TBX15 rs98422, DNM3 rs1011731, RAD51B rs8017304, and rs2588809 Gene Polymorphisms and Associations With Pituitary Adenoma
GABIJA JUKNYTĖ, INGA LAURINAITYTĖ, ALVITA VILKEVIČIŪTĖ, GRETA GEDVILAITĖ, BRIGITA GLEBAUSKIENĖ, LORESA KRIAUČIŪNIENĖ, RASA LIUTKEVIČIENĖ
In Vivo. 2021 Mar-Apr; 35(2): 815–826. Published online 2021 Mar 3. doi: 10.21873/invivo.12322
PMCID:
PMC8045120
AbstractArticlePDF–186K
9.
Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor
Luke A. Greenhough, Chih-Chao Liang, Ondrej Belan, Simone Kunzelmann, Sarah Maslen, Monica C. Rodrigo-Brenni, Roopesh Anand, Mark Skehel, Simon J. Boulton, Stephen C. West
Nature. Author manuscript; available in PMC 2023 Jul 20.
Published in final edited form as: Nature. 2023 Jun 21; 619(7970): 650–657. Published online 2023 Jun 21. doi: 10.1038/s41586-023-06179-1
PMCID:
PMC7614784
AbstractArticlePDF–8.2M
10.
Sequential role of RAD51 paralog complexes in replication fork remodeling and restart
Matteo Berti, Federico Teloni, Sofija Mijic, Sebastian Ursich, Jevgenij Fuchs, Maria Dilia Palumbieri, Jana Krietsch, Jonas A. Schmid, Edwige B. Garcin, Stéphanie Gon, Mauro Modesti, Matthias Altmeyer, Massimo Lopes
Nat Commun. 2020; 11: 3531. Published online 2020 Jul 15. doi: 10.1038/s41467-020-17324-z
PMCID:
PMC7363682
AbstractArticlePDF–2.1M
11.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
12.
Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells
Edwige B. Garcin, Stéphanie Gon, Meghan R. Sullivan, Gregory J. Brunette, Anne De Cian, Jean-Paul Concordet, Carine Giovannangeli, Wilhelm G. Dirks, Sonja Eberth, Kara A. Bernstein, Rohit Prakash, Maria Jasin, Mauro Modesti
PLoS Genet. 2019 Oct; 15(10): e1008355. Published online 2019 Oct 4. doi: 10.1371/journal.pgen.1008355
PMCID:
PMC6795472
AbstractArticlePDF–2.6M
13.
RAD51D splice variants and cancer-associated mutations reveal XRCC2 interaction to be critical for homologous recombination
Robert A. Baldock, Catherine A. Pressimone, Jared M. Baird, Anton Khodakov, Thong T. Luong, McKenzie K. Grundy, Chelsea M. Smith, Yoav Karpenshif, Dominique S. Bratton-Palmer, Edwige B. Garcin, Stéphanie Gon, Mauro Modesti, Kara A. Bernstein
DNA Repair (Amst) Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: DNA Repair (Amst). 2019 Apr; 76: 99–107. Published online 2019 Feb 23. doi: 10.1016/j.dnarep.2019.02.008
PMCID:
PMC6508892
AbstractArticlePDF–1.1M
14.
USP45 and Spindly are part of the same complex implicated in cell migration
Claudia Conte, Eric R. Griffis, Ian Hickson, Ana B. Perez-Oliva
Sci Rep. 2018; 8: 14375. Published online 2018 Sep 26. doi: 10.1038/s41598-018-32685-8
PMCID:
PMC6158257
AbstractArticlePDF–2.3M
15.
Discovery of Mutations in Homologous Recombination Genes in African-American Women with Breast Cancer
Yuan Chun Ding, Aaron W. Adamson, Linda Steele, Adam M. Bailis, Esther M. John, Gail Tomlinson, Susan L. Neuhausen
Fam Cancer. Author manuscript; available in PMC 2019 Apr 1.
Published in final edited form as: Fam Cancer. 2018 Apr; 17(2): 187–195. doi: 10.1007/s10689-017-0036-4
PMCID:
PMC5834346
AbstractArticlePDF–354K
16.
Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics
Y Li, H Sun, C Zhang, J Liu, H Zhang, F Fan, R A Everley, X Ning, Y Sun, J Hu, J Liu, J Zhang, W Ye, X Qiu, S Dai, B Liu, H Xu, S Fu, S P Gygi, C Zhou
Oncogene. 2017 Dec 14; 36(50): 6839–6849. Published online 2017 Aug 28. doi: 10.1038/onc.2017.289
PMCID:
PMC5735297
AbstractArticlePDF–1.3M
17.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
18.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
19.
Polymorphisms of RAD51B are associated with rheumatoid arthritis and erosion in rheumatoid arthritis patients
Liqiang Zhi, Shuxin Yao, Wenlong Ma, Weijie Zhang, Honggan Chen, Meng Li, Jianbing Ma
Sci Rep. 2017; 7: 45876. Published online 2017 Mar 31. doi: 10.1038/srep45876
PMCID:
PMC5374468
AbstractArticlePDF–583K
20.
Methylation of RAD51B, XRCC3 and other homologous recombination genes is associated with expression of immune checkpoints and an inflammatory signature in squamous cell carcinoma of the head and neck, lung and cervix
Damian T. Rieke, Sebastian Ochsenreither, Konrad Klinghammer, Tanguy Y. Seiwert, Frederick Klauschen, Inge Tinhofer, Ulrich Keilholz
Oncotarget. 2016 Nov 15; 7(46): 75379–75393. Published online 2016 Sep 23. doi: 10.18632/oncotarget.12211
PMCID:
PMC5342748
AbstractArticlePDF–6.2M

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