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Items: 1 to 20 of 96

1.
Molecular Factors in PAD2 (PADI2) and PAD4 (PADI4) Are Associated with Interstitial Lung Disease Susceptibility in Rheumatoid Arthritis Patients
Karol J. Nava-Quiroz, Jorge Rojas-Serrano, Gloria Pérez-Rubio, Ivette Buendia-Roldan, Mayra Mejía, Juan Carlos Fernández-López, Pedro Rodríguez-Henríquez, Noé Ayala-Alcantar, Espiridión Ramos-Martínez, Luis Alberto López-Flores, Alma D. Del Ángel-Pablo, Ramcés Falfán-Valencia
Cells. 2023 Sep; 12(18): 2235. Published online 2023 Sep 8. doi: 10.3390/cells12182235
PMCID:
PMC10527441
AbstractArticlePDF–1.6M
2.
New insights into cancer: MDM2 binds to the citrullinating enzyme PADI4
Salomé Araujo‐Abad, Bruno Rizzuti, Adrián Villamarin‐Ortiz, David Pantoja‐Uceda, Celia M. Moreno‐Gonzalez, Olga Abian, Adrián Velazquez‐Campoy, José L. Neira, Camino de Juan Romero
Protein Sci. 2023 Aug; 32(8): e4723. Published online 2023 Aug 1. doi: 10.1002/pro.4723
PMCID:
PMC10364586
AbstractArticlePDF–7.4M
3.
An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression
Alexandra Indeglia, Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke, Nicole A. Kirven, Chunlei Shao, Lei Ke, Scott Lovell, Thibaut Barnoud, David Y. Lu, Cindy Lin, Toshitha Kannan, Kevin P. Battaile, Tyler Hong Loong Yang, Isabela Batista Oliva, Daniel T. Claiborne, Peter Vogel, Lijun Liu, Qin Liu, Yulia Nefedova, Joel Cassel, Noam Auslander, Andrew V. Kossenkov, John Karanicolas, Maureen E. Murphy
Cancer Discov. 2023 Jul 7; 13(7): 1696–1719. Published online 2023 May 4. doi: 10.1158/2159-8290.CD-22-1315
PMCID:
PMC10326602
AbstractArticlePDF–24M
4.
Implications of Peptidyl Arginine Deiminase 4 gene transcription and polymorphisms in susceptibility to rheumatoid arthritis in an Iranian population
Zahra Bagheri-Hosseinabadi, Mohammad Reza Mirzaei, Ozrasadat Esmaeili, Fatemeh Asadi, Hassan Ahmadinia, Banafshe Shamsoddini, Mitra Abbasifard
BMC Med Genomics. 2023; 16: 104. Published online 2023 May 16. doi: 10.1186/s12920-023-01532-9
PMCID:
PMC10186752
AbstractArticlePDF–1.3M
5.
PADI4 and IL-33 gene polymorphisms with susceptibility to systemic lupus erythematosus and juvenile idiopathic arthritis, a systematic review and meta-analysis
Bo Zheng, Pingping Cai, Yangjun Chen, Yuechao Wu, Hongyan Liu
Medicine (Baltimore) 2023 May 5; 102(18): e33700. Published online 2023 May 5. doi: 10.1097/MD.0000000000033700
PMCID:
PMC10158862
AbstractArticlePDF–811K
6.
Neutrophil PAD4: how does it function in cancer beyond promoting NETosis?
Laura Garcia-Gerique, Yulia Nefedova
Oncotarget. 2023; 14: 258–260. Published online 2023 Mar 24. doi: 10.18632/oncotarget.28369
PMCID:
PMC10038352
ArticlePDF–617K
7.
PADI4 and IL-33 gene polymorphisms associated with differential susceptibility to juvenile-onset systemic lupus erythematosus and juvenile idiopathic arthritis in Chinese children
Yu Zhou, Xinle Liu
Medicine (Baltimore) 2022 Dec 16; 101(50): e31598. Published online 2022 Dec 16. doi: 10.1097/MD.0000000000031598
PMCID:
PMC9771228
AbstractArticlePDF–497K
8.
A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates
Jéssika Cristina Chagas Lesbon, Taismara Kustro Garnica, Pedro Luiz Porfírio Xavier, Arina Lázaro Rochetti, Rui Manuel Reis, Susanne Müller, Heidge Fukumasu
Int J Mol Sci. 2022 Oct; 23(19): 11911. Published online 2022 Oct 7. doi: 10.3390/ijms231911911
PMCID:
PMC9570250
AbstractArticlePDF–2.1M
9.
Changes in Tumor Necrosis Factor α (TNFα) and Peptidyl Arginine Deiminase 4 (PAD-4) Levels in Serum of General Treated Psoriatic Patients
Joanna Czerwińska, Marta Kasprowicz-Furmańczyk, Waldemar Placek, Agnieszka Owczarczyk-Saczonek
Int J Environ Res Public Health. 2022 Jul; 19(14): 8723. Published online 2022 Jul 18. doi: 10.3390/ijerph19148723
PMCID:
PMC9324472
AbstractArticlePDF–1.3M
10.
PADI4 promotes epithelial-mesenchymal transition(EMT) in gastric cancer via the upregulation of interleukin 8
Xiao-tian Chang, Hui Wu, Hui-lin Li, Hong-lei Li, Ya-bing Zheng
BMC Gastroenterol. 2022; 22: 25. Published online 2022 Jan 19. doi: 10.1186/s12876-022-02097-0
PMCID:
PMC8767667
AbstractArticlePDF–6.1M
11.
PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking
Laura Massarenti, Christian Enevold, Dres Damgaard, Niels Ødum, Peter Garred, Morten Frisch, Miriam A. Shelef, Søren Jacobsen, Claus Henrik Nielsen
Front Immunol. 2021; 12: 707690. Published online 2021 Oct 18. doi: 10.3389/fimmu.2021.707690
PMCID:
PMC8558474
AbstractArticlePDF–1.1M
12.
Genetic Variation in PADI6-PADI4 on 1p36.13 Is Associated with Common Forms of Human Generalized Epilepsy
Russell J. Buono, Jonathan P. Bradfield, Zhi Wei, Michael R. Sperling, Dennis J. Dlugos, Michael D. Privitera, Jacqueline A. French, Warren Lo, Patrick Cossette, Steven C. Schachter, Heather Basehore, Falk W. Lohoff, Struan F. A. Grant, Thomas N. Ferraro, Hakon Hakonarson
Genes (Basel) 2021 Sep; 12(9): 1441. Published online 2021 Sep 18. doi: 10.3390/genes12091441
PMCID:
PMC8472138
AbstractArticlePDF–2.8M
13.
Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization
Yufeng Wang, Yajing Lyu, Kangsheng Tu, Qiuran Xu, Yongkang Yang, Shaima Salman, Nguyet Le, Haiquan Lu, Chelsey Chen, Yayun Zhu, Ru Wang, Qingguang Liu, Gregg L. Semenza
Sci Adv. 2021 Aug; 7(35): eabe3771. Published online 2021 Aug 27. doi: 10.1126/sciadv.abe3771
PMCID:
PMC8397272
AbstractArticlePDF–10M
14.
PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune‐mediated disease
Xiaosong Liu, Tom Arfman, Kanin Wichapong, Chris P. M. Reutelingsperger, Jan Voorberg, Gerry A. F. Nicolaes
J Thromb Haemost. 2021 Jul; 19(7): 1607–1617. Published online 2021 May 12. doi: 10.1111/jth.15313
PMCID:
PMC8360066
AbstractArticlePDF–1.3M
15.
Peptidylarginine deiminase IV (PADI4) regulates breast cancer stem cells via a novel tumor cell-autonomous suppressor role
Nellie Moshkovich, Humberto J. Ochoa, Binwu Tang, Howard H. Yang, Yuan Yang, Jing Huang, Maxwell P. Lee, Lalage M. Wakefield
Cancer Res. Author manuscript; available in PMC 2021 Jul 21.
Published in final edited form as: Cancer Res. 2020 Jun 1; 80(11): 2125–2137. Published online 2020 Apr 7. doi: 10.1158/0008-5472.CAN-19-3018
PMCID:
PMC8294167
AbstractArticlePDF–2.2M
16.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
17.
Factors Associated with Promoted Proliferation of Osteosarcoma by Peptidylarginine Deiminase 4
Jianping Guo, Lei Yin, Xuezhong Zhang, Peng Su, Qiaoli Zhai
Biomed Res Int. 2021; 2021: 5596014. Published online 2021 May 15. doi: 10.1155/2021/5596014
PMCID:
PMC8147525
AbstractArticlePDF–2.2M
18.
Inhibition of PAD4 enhances radiosensitivity and inhibits aggressive phenotypes of nasopharyngeal carcinoma cells
Hao Chen, Min Luo, Xiangping Wang, Ting Liang, Chaoyuan Huang, Changjie Huang, Lining Wei
Cell Mol Biol Lett. 2021; 26: 9. Published online 2021 Mar 16. doi: 10.1186/s11658-021-00251-2
Correction in:
Cell Mol Biol Lett. 2021; 26: 55.
Correction in:
Cell Mol Biol Lett. 2023; 28: 29.
PMCID:
PMC7962337
AbstractArticlePDF–5.1M
19.
Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4- and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes
Yuko Okamato, Tusharkanti Ghosh, Tsukasa Okamoto, Ronald P. Schuyler, Jennifer Seifert, Laura Lenis Charry, Ashley Visser, Marie Feser, Chelsie Fleischer, Chong Pedrick, Justin August, Laurakay Moss, Elizabeth A. Bemis, Jill M. Norris, Kristine A. Kuhn, M. Kristen Demoruelle, Kevin D. Deane, Debashis Ghosh, V. Michael Holers, Elena W.Y. Hsieh
J Autoimmun. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: J Autoimmun. 2021 Feb; 117: 102581. Published online 2020 Dec 9. doi: 10.1016/j.jaut.2020.102581
PMCID:
PMC7855988
AbstractArticlePDF–1.2M
20.
Endogenous PAD4 in Breast Cancer Cells Mediates Cancer Extracellular Chromatin Network Formation and Promotes Lung Metastasis
Lai Shi, Huanling Yao, Zheng Liu, Ming Xu, Allan Tsung, Yanming Wang
Mol Cancer Res. Author manuscript; available in PMC 2020 Nov 16.
Published in final edited form as: Mol Cancer Res. 2020 May; 18(5): 735–747. Published online 2020 Mar 19. doi: 10.1158/1541-7786.MCR-19-0018
PMCID:
PMC7668292
AbstractArticlePDF–2.4M

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