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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 87489582.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 75862523.

Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRɑ) signal through MAPK/ERK pathway in human prostate tissues: A morphological and biomolecular study

Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua, Daniela Marzioni, Roberta Mazzucchelli

Eur J Histochem. 2020 Oct 19; 64(4): 3147. Published online 2020 Oct 19. doi: 10.4081/ejh.2020.3147

PMCID:: PMC7586252

Abstract Article PDF–568K

Select item 70874544.

Anti-tumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma

Jun W. Kim, Cesar P. Marquez, Kaja Kostyrko, Amanda L. Koehne, Kieren Marini, David R. Simpson, Alex G. Lee, Stanley G. Leung, Leanne C. Sayles, Joseph Shrager, Irene Ferrer, Luis Paz-Ares, Melanie Hayden Gephart, Silvestre Vicent, Jennifer R. Cochran, E. Alejandro Sweet-Cordero

Nat Med. Author manuscript; available in PMC 2020 Aug 7.

Published in final edited form as: Nat Med. 2019 Nov; 25(11): 1783–1795. Published online 2019 Nov 7. doi: 10.1038/s41591-019-0612-2

PMCID:: PMC7087454

Abstract Article PDF–7.0M

Select item 67533465.

microRNA-146a Promotes Growth of Acute Leukemia Cells by Downregulating Ciliary Neurotrophic Factor Receptor and Activating JAK2/STAT3 Signaling

Lei Wang, Hongyan Zhang, Donghong Lei

Yonsei Med J. 2019 Oct 1; 60(10): 924–934. Published online 2019 Sep 16. doi: 10.3349/ymj.2019.60.10.924

PMCID:: PMC6753346

Abstract Article PDF–1.2M

Select item 62982546.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 55572927.

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik

Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.

Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834

PMCID:: PMC5557292

Abstract Article PDF–3.4M

Select item 55392848.

Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas

Kun Fan, Xiaowen Wang, Jingwen Zhang, Romela Irene Ramos, Haibo Zhang, Chunjie Li, Dan Ye, Jiansheng Kang, Diego M. Marzese, Dave S. B. Hoon, Wei Hua

Sci Rep. 2017; 7: 7079. Published online 2017 Aug 1. doi: 10.1038/s41598-017-07124-9

PMCID:: PMC5539284

Abstract Article PDF–1.2M

Select item 48362749.

Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover

Jakob Vejby Larsen, Anders Mejer Kristensen, Lone Tjener Pallesen, Johannes Bauer, Christian Bjerggaard Vægter, Morten Schallburg Nielsen, Peder Madsen, Claus Munck Petersen

Mol Cell Biol. 2016 Apr 15; 36(8): 1272–1286. Prepublished online 2016 Feb 8. Published online 2016 Apr 1. doi: 10.1128/MCB.00917-15

PMCID:: PMC4836274

Abstract Article PDF–2.8M

Select item 476203910.

CNTF receptor subunit α as a marker for glioma tumor-initiating cells and tumor grade

Jie Lu, Alexander Ksendzovsky, Chunzhang Yang, Gautam U. Mehta, Raymund L. Yong, Robert J. Weil, Deric M. Park, Harry M. Mushlin, Xueping Fang, Brian M. Balgley, Dae-Hee Lee, Cheng S. Lee, Russell R. Lonser, Zhengping Zhuang

J Neurosurg. Author manuscript; available in PMC 2016 Feb 22.

Published in final edited form as: J Neurosurg. 2012 Dec; 117(6): 1022–1031. Published online 2012 Oct 12. doi: 10.3171/2012.9.JNS1212

PMCID:: PMC4762039

Abstract Article PDF–1.7M

Select item 414024811.

The Amino Acid Exchange R28E in Ciliary Neurotrophic Factor (CNTF) Abrogates Interleukin-6 Receptor-dependent but Retains CNTF Receptor-dependent Signaling via Glycoprotein 130 (gp130)/Leukemia Inhibitory Factor Receptor (LIFR)

Eva-Maria Wagener, Matthias Aurich, Samadhi Aparicio-Siegmund, Doreen M. Floss, Christoph Garbers, Kati Breusing, Björn Rabe, Ralf Schwanbeck, Joachim Grötzinger, Stefan Rose-John, Jürgen Scheller

J Biol Chem. 2014 Jun 27; 289(26): 18442–18450. Published online 2014 May 6. doi: 10.1074/jbc.M114.568857

PMCID:: PMC4140248

Abstract Article PDF–1.5M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316628313.

CNTF Mediates Neurotrophic Factor Secretion and Fluid Absorption in Human Retinal Pigment Epithelium

Rong Li, Rong Wen, Tina Banzon, Arvydas Maminishkis, Sheldon S. Miller

PLoS One. 2011; 6(9): e23148. Published online 2011 Sep 2. doi: 10.1371/journal.pone.0023148

PMCID:: PMC3166283

Abstract Article PDF–1.2M

Select item 301327614.

Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by α-synuclein

Jun Liu, Min Shi, Zhen Hong, JianPeng Zhang, Joshua Bradner, Thomas Quinn, Richard P. Beyer, Patrick L. Mcgeer, ShengDi Chen, Jing Zhang

Proteomics. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Proteomics. 2010 Jun; 10(11): 2138–2150. doi: 10.1002/pmic.200900745

PMCID:: PMC3013276

Abstract Article PDF–1.0M

Select item 293755715.

Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor β Heterodimer

Jakob Vejby Larsen, Maria Hansen, Bjarne Møller, Peder Madsen, Jürgen Scheller, Morten Nielsen, Claus Munck Petersen

Mol Cell Biol. 2010 Sep; 30(17): 4175–4187. Published online 2010 Jun 28. doi: 10.1128/MCB.00274-10

PMCID:: PMC2937557

Abstract Article PDF–2.5M

Select item 289646416.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 286078317.

Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer’s disease

J Chapuis, D Hot, F Hansmannel, O Kerdraon, S Ferreira, C Hubans, CA Maurage, L Huot, F Bensemain, G Laumet, AM Ayral, N Fievet, JJ Hauw, ST DeKosky, Y Lemoine, T Iwatsubo, F Wavrant-Devrièze, JF Dartigues, C Tzourio, L Buée, F Pasquier, C Berr, D Mann, C Lendon, A Alpérovitch, MI Kamboh, P Amouyel, JC Lambert

Mol Psychiatry. Author manuscript; available in PMC 2010 Apr 28.

Published in final edited form as: Mol Psychiatry. 2009 Nov; 14(11): 1004–1016. Published online 2009 Feb 10. doi: 10.1038/mp.2009.10

PMCID:: PMC2860783

Abstract Article PDF–1.3M

Select item 279151818.

High-Density Association Study of 383 Candidate Genes for Volumetric BMD at the Femoral Neck and Lumbar Spine Among Older Men

Laura M. Yerges, Lambertus Klei, Jane A. Cauley, Kathryn Roeder, Candace M. Kammerer, Susan P. Moffett, Kristine E. Ensrud, Cara S. Nestlerode, Lynn M. Marshall, Andrew R. Hoffman, Cora Lewis, Thomas F. Lang, Elizabeth Barrett-Connor, Robert E. Ferrell, Eric S. Orwoll, Joseph M. Zmuda

J Bone Miner Res. 2009 Dec; 24(12): 2039–2049. Published online 2009 May 18. doi: 10.1359/JBMR.090524

PMCID:: PMC2791518

Abstract Article PDF–759K

Select item 269579419.

Humanin Inhibits Neuronal Cell Death by Interacting with a Cytokine Receptor Complex or Complexes Involving CNTF Receptor α/WSX-1/gp130

Yuichi Hashimoto, Megumi Kurita, Sadakazu Aiso, Ikuo Nishimoto, Masaaki Matsuoka

Mol Biol Cell. 2009 Jun 15; 20(12): 2864–2873. doi: 10.1091/mbc.E09-02-0168

PMCID:: PMC2695794

Abstract Article PDF–2.4M

Select item 260719620.

Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex

Georgios Skiniotis, Patrick Lupardus, Monika Martick, Thomas Walz, K. Christopher Garcia

Mol Cell. Author manuscript; available in PMC 2009 Mar 5.

Published in final edited form as: Mol Cell. 2008 Sep 5; 31(5): 737–748. doi: 10.1016/j.molcel.2008.08.011

PMCID:: PMC2607196

Abstract Article PDF–7.1M

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