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Select item 108537781.

Harmonin homology domain-mediated interaction of RTEL1 helicase with RPA and DNA provides insights into its recruitment to DNA repair sites

Niranjan Kumar, Arushi Taneja, Meenakshi Ghosh, Ulli Rothweiler, Nagalingam Ravi Sundaresan, Mahavir Singh

Nucleic Acids Res. 2024 Feb 9; 52(3): 1450–1470. Published online 2023 Dec 28. doi: 10.1093/nar/gkad1208

PMCID:: PMC10853778

Abstract Article PDF–3.4M

Select item 107649582.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 106176733.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105859294.

Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma

Yanchun Feng, Yingming Jiang, Jun Liu, Jiaqi Liu, Mengchen Shi, Junxiong Chen, Jingdan Zhang, Yu Tian, Xiangling Yang, Huanliang Liu

J Transl Med. 2023; 21: 738. Published online 2023 Oct 19. doi: 10.1186/s12967-023-04574-w

PMCID:: PMC10585929

Abstract Article PDF–3.1M

Select item 104805355.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 104799646.

Structural characterization of human RPA70N association with DNA damage response proteins

Yeyao Wu, Wangmi Fu, Ning Zang, Chun Zhou

eLife. 2023; 12: e81639. Published online 2023 Sep 5. doi: 10.7554/eLife.81639

PMCID:: PMC10479964

Abstract Article PDF–20M

Select item 102879057.

Proper RPA acetylation promotes accurate DNA replication and repair

Xiaoli Gan, Yueyue Zhang, Donghao Jiang, Jingyao Shi, Han Zhao, Chengyu Xie, Yanyan Wang, Jingyan Xu, Xinghua Zhang, Gang Cai, Hailong Wang, Jun Huang, Xuefeng Chen

Nucleic Acids Res. 2023 Jun 23; 51(11): 5565–5583. Published online 2023 May 4. doi: 10.1093/nar/gkad291

PMCID:: PMC10287905

Abstract Article PDF–3.3M

Select item 102678398.

Replication Protein A Enhances Kinetics of Uracil DNA Glycosylase on ssDNA and Across DNA Junctions: Explored with a DNA Repair Complex Produced with SpyCatcher/SpyTag Ligation

Sharon N. Greenwood, Rashmi S. Kulkarni, Michel Mikhail, Brian P. Weiser

Chembiochem. Author manuscript; available in PMC 2024 May 16.

Published in final edited form as: Chembiochem. 2023 May 16; 24(10): e202200765. Published online 2023 Apr 18. doi: 10.1002/cbic.202200765

PMCID:: PMC10267839

Abstract Article PDF–1.5M

Select item 102502339.

RPA engages telomeric G-quadruplexes more effectively than CST

Conner L Olson, Alexandra T Barbour, Thomas A Wieser, Deborah S Wuttke

Nucleic Acids Res. 2023 Jun 9; 51(10): 5073–5086. Published online 2023 May 4. doi: 10.1093/nar/gkad315

PMCID:: PMC10250233

Abstract Article PDF–1.0M

Select item 1023742210.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1019394011.

The RPA–RNF20–SNF2H cascade promotes proper chromosome segregation and homologous recombination repair

Jimin Li, Jingyu Zhao, Xiaoli Gan, Yanyan Wang, Donghao Jiang, Liang Chen, Fangwei Wang, Jingyan Xu, Huadong Pei, Jun Huang, Xuefeng Chen

Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2303479120. Published online 2023 May 8. doi: 10.1073/pnas.2303479120

PMCID:: PMC10193940

Abstract Article PDF–15M

Select item 1016023712.

PRIMPOL competes with RAD51 to resolve G-quadruplex-induced replication stress via its interaction with RPA: PRIMPOL resolves G4-induced replication stress

Tingfang Li, Lu Tang, Haomeng Kou, Feng Wang

Acta Biochim Biophys Sin (Shanghai) 2023 Mar; 55(3): 498–507. Published online 2022 Nov 9. doi: 10.3724/abbs.2022165

PMCID:: PMC10160237

Abstract Article PDF–2.1M

Select item 998681713.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762

PMCID:: PMC9986817

Abstract Article PDF–3.5M

Select item 979798814.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144