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Items: 1 to 20 of 54

1.
Effects of Spermine Synthase Deficiency in Mesenchymal Stromal Cells Are Rescued by Upstream Inhibition of Ornithine Decarboxylase
Amin Cressman, David Morales, Zhenyang Zhang, Bryan Le, Jackson Foley, Tracy Murray-Stewart, Damian C. Genetos, Fernando A. Fierro
Int J Mol Sci. 2024 Mar; 25(5): 2463. Published online 2024 Feb 20. doi: 10.3390/ijms25052463
PMCID:
PMC10931026
AbstractArticlePDF–4.7M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Expanding the phenotype: Four new cases and hope for treatment in Bachmann‐Bupp syndrome
Elizabeth A. VanSickle, Julianne Michael, André S. Bachmann, Surender Rajasekaran, Jeremy W. Prokop, Ruben Kuzniecky, Floris C. Hofstede, Katharina Steindl, Anita Rauch, Mark H. Lipson, Caleb P. Bupp
Am J Med Genet A. 2021 Nov; 185(11): 3485–3493. Published online 2021 Sep 3. doi: 10.1002/ajmg.a.62473
Correction in:
Am J Med Genet A. 2023 Jul; 191(7): 2003.
PMCID:
PMC9292803
AbstractArticlePDF–1.8M
4.
Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane
X. Edward Zhou, Kelly Suino-Powell, Chad R. Schultz, Bilal Aleiwi, Joseph S. Brunzelle, Jared Lamp, Irving E. Vega, Edmund Ellsworth, André S. Bachmann, Karsten Melcher
Biochem J. Author manuscript; available in PMC 2022 May 23.
Published in final edited form as: Biochem J. 2021 Dec 10; 478(23): 4137–4149. doi: 10.1042/BCJ20210647
PMCID:
PMC9125680
AbstractArticlePDF–2.1M
5.
Ornithine Decarboxylase (ODC1) gene variant (rs2302615) is associated with gastric cancer independently of Helicobacter pylori CagA serostatus
Anna K Miller, Gloria Tavera, Ricardo L Dominguez, M Constanza Camargo, Tim Waterboer, Keith T Wilson, Scott M Williams, Douglas R Morgan
Oncogene. Author manuscript; available in PMC 2022 Apr 1.
Published in final edited form as: Oncogene. 2021 Oct; 40(40): 5963–5969. Published online 2021 Aug 10. doi: 10.1038/s41388-021-01981-5
PMCID:
PMC8692072
AbstractArticlePDF–364K
6.
Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease
Surender Rajasekaran, Caleb P Bupp, Mara Leimanis-Laurens, Ankit Shukla, Christopher Russell, Joseph Junewick, Emily Gleason, Elizabeth A VanSickle, Yvonne Edgerly, Bryan M Wittmann, Jeremy W Prokop, André S Bachmann
eLife. 2021; 10: e67097. Published online 2021 Jul 20. doi: 10.7554/eLife.67097
PMCID:
PMC8291972
AbstractArticlePDF–1.6M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
Brain Neurons Express Ornithine Decarboxylase‐Activating Antizyme Inhibitor 2 with Accumulation in Alzheimer's Disease
Laura T. Mäkitie, Kristiina Kanerva, Tuomo Polvikoski, Anders Paetau, Leif C. Andersson
Brain Pathol. 2010 May; 20(3): 571–580. Published online 2009 Sep 22. doi: 10.1111/j.1750-3639.2009.00334.x
PMCID:
PMC8094758
AbstractArticlePDF–743K
9.
Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development
Jeremy W. Prokop, Caleb P. Bupp, Austin Frisch, Stephanie M. Bilinovich, Daniel B. Campbell, Daniel Vogt, Chad R. Schultz, Katie L. Uhl, Elizabeth VanSickle, Surender Rajasekaran, André S. Bachmann
Genes (Basel) 2021 Apr; 12(4): 470. Published online 2021 Mar 25. doi: 10.3390/genes12040470
PMCID:
PMC8064465
AbstractArticlePDF–2.6M
10.
Oesophageal squamous cell carcinoma–associated IL‐33 rewires macrophage polarization towards M2 via activating ornithine decarboxylase
Shijie Mai, Le Liu, Jianjun Jiang, Pengfei Ren, Dingwei Diao, Haofei Wang, Kaican Cai
Cell Prolif. 2021 Feb; 54(2): e12960. Published online 2020 Dec 10. doi: 10.1111/cpr.12960
PMCID:
PMC7848962
AbstractArticlePDF–1.9M
11.
FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer
Li Qiu, Linfei Hu, Huijuan Wang, Jinling Li, Xianhui Ruan, Bingsheng Sun, Jingtai Zhi, Xiangqian Zheng, Lin Gu, Ming Gao, Pengzhou Kong, Jun Zhang
Cell Death Dis. 2020 Oct; 11(10): 839. Published online 2020 Oct 9. doi: 10.1038/s41419-020-03052-1
PMCID:
PMC7547721
AbstractArticlePDF–2.8M
12.
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy
Renee C. Geck, Jackson R. Foley, Tracy Murray Stewart, John M. Asara, Robert A. Casero, Jr., Alex Toker
J Biol Chem. 2020 May 8; 295(19): 6263–6277. Published online 2020 Mar 5. doi: 10.1074/jbc.RA119.012376
PMCID:
PMC7212655
AbstractArticlePDF–5.0M
13.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
14.
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection
Wai Fook Leong, Vincent T. K. Chow
Cell Microbiol. 2006 Apr; 8(4): 565–580. Published online 2005 Nov 8. doi: 10.1111/j.1462-5822.2005.00644.x
PMCID:
PMC7162300
AbstractArticlePDF–345K
15.
Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1
Lars Erichsen, Hans-Helge Seifert, Wolfgang A. Schulz, Michèle J. Hoffmann, Günter Niegisch, Marcos J. Araúzo-Bravo, Marcelo L. Bendhack, Cedric Poyet, Thomas Hermanns, Agnes Beermann, Mohamed Hassan, Lisa Theis, Wardah Mahmood, Simeon Santourlidis
Sci Rep. 2020; 10: 3808. Published online 2020 Mar 2. doi: 10.1038/s41598-020-60796-8
PMCID:
PMC7052216
AbstractArticlePDF–1.9M
16.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
17.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
18.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
19.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
20.
Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling
Amita Shukla-Dave, Mireia Castillo-Martin, Ming Chen, Jose Lobo, Nataliya Gladoun, Ana Collazo-Lorduy, Faisal M. Khan, Vladimir Ponomarev, Zhengzi Yi, Weijia Zhang, Pier P. Pandolfi, Hedvig Hricak, Carlos Cordon-Cardo
Am J Pathol. 2016 Dec; 186(12): 3131–3145. doi: 10.1016/j.ajpath.2016.08.021
PMCID:
PMC5225291
AbstractArticlePDF–2.3M

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