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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 66892892.

Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling

Beatriz Garcia-Diaz, Corinne Bachelin, Fanny Coulpier, Gaspard Gerschenfeld, Cyrille Deboux, Violetta Zujovic, Patrick Charnay, Piotr Topilko, Anne Baron-Van Evercooren

Acta Neuropathol. 2019; 138(3): 457–476. Published online 2019 Apr 22. doi: 10.1007/s00401-019-02011-1

PMCID:: PMC6689289

Abstract Article PDF–13M

Select item 66730893.

EphB Receptors Regulate Stem/Progenitor Cell Proliferation, Migration, and Polarity during Hippocampal Neurogenesis

Michael J. Chumley, Timothy Catchpole, Robert E. Silvany, Steven G. Kernie, Mark Henkemeyer

J Neurosci. 2007 Dec 5; 27(49): 13481–13490. doi: 10.1523/JNEUROSCI.4158-07.2007

PMCID:: PMC6673089

Abstract Article PDF–598K

Select item 61604684.

Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism

Tao Wu, Bi-Qi Zhang, John Raelson, Yu-Mei Yao, Huan-Dong Wu, Zao-Xian Xu, Francois-christophe Marois-blanchet, Muhammad Ramzan Tahir, Yujia Wang, W. Edward Bradley, Hongyu Luo, Jiangping Wu, Jian-Zhong Sheng, Shen-Jiang Hu

Sci Rep. 2018; 8: 14497. Published online 2018 Sep 27. doi: 10.1038/s41598-018-32836-x

PMCID:: PMC6160468

Abstract Article PDF–1.2M

Select item 61289055.

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability

Hema Adhikari, Christopher M. Counter

Nat Commun. 2018; 9: 3646. Published online 2018 Sep 7. doi: 10.1038/s41467-018-05692-6

PMCID:: PMC6128905

Abstract Article PDF–2.2M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53410217.

Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene

Johanne Tremblay, Yujia Wang, John Raelson, Francois-Christophe Marois-Blanchet, Zenghui Wu, Hongyu Luo, Edward Bradley, John Chalmers, Mark Woodward, Stephen Harrap, Pavel Hamet, Jiangping Wu

Sci Rep. 2017; 7: 44114. Published online 2017 Mar 8. doi: 10.1038/srep44114

PMCID:: PMC5341021

Abstract Article PDF–689K

Select item 53123878.

Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer

Ghazal Efazat, Metka Novak, Vitaliy O. Kaminskyy, Luigi De Petris, Lena Kanter, Therese Juntti, Per Bergman, Boris Zhivotovsky, Rolf Lewensohn, Petra Hååg, Kristina Viktorsson

Oncotarget. 2016 Sep 13; 7(37): 60332–60347. Published online 2016 Aug 11. doi: 10.18632/oncotarget.11219

PMCID:: PMC5312387

Abstract Article PDF–10M

Select item 51502339.

The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility

Yujia Wang, Zenghui Wu, Hongyu Luo, Junzheng Peng, John Raelson, Georg B. Ehret, Patricia B. Munroe, Ekatherina Stoyanova, Zhao Qin, Guy Cloutier, W. Edward Bradley, Tao Wu, Jian-Zhong Shen, Shenjiang Hu, Jiangping Wu

Sci Rep. 2016; 6: 38976. Published online 2016 Dec 12. doi: 10.1038/srep38976

PMCID:: PMC5150233

Abstract Article PDF–803K

Select item 471375410.

Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination

Yasir A. Syed, Chao Zhao, Don Mahad, Wiebke Möbius, Friedrich Altmann, Franziska Foss, Aycan Sentürk, Amparo Acker-Palmer, Gert Lubec, Kathryn Lilley, Robin J. M. Franklin, Klaus-A. Nave, Mark R. N. Kotter

Acta Neuropathol. 2016; 131(2): 281–298. Published online 2015 Dec 19. doi: 10.1007/s00401-015-1521-1

Correction in:: Acta Neuropathol. 2016; 132: 157.

Correction in:: Acta Neuropathol. 2017; 134(1): 167–168.

PMCID:: PMC4713754

Abstract Article PDF–4.3M

Select item 461721111.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 394102112.

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses

Elena Seiradake, Andreas Schaupp, Daniel del Toro Ruiz, Rainer Kaufmann, Nikolaos Mitakidis, Karl Harlos, A Radu Aricescu, Rüdiger Klein, E Yvonne Jones

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Mar 4.

Published in final edited form as: Nat Struct Mol Biol. 2013 Aug; 20(8): 958–964. Published online 2013 Jun 30. doi: 10.1038/nsmb.2617

PMCID:: PMC3941021

Abstract Article PDF–2.7M

Select item 326170813.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 322018614.

Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes

Lin T. Guey, Montserrat García-Closas, Cristiane Murta-Nascimento, Josep Lloreta, Laia Palencia, Manolis Kogevinas, Nathaniel Rothman, Gemma Vellalta, Malu Calle, Gaëlle Marenne, Adonina Tardón, Alfredo Carrato, Reina García-Closas, Consol Serra, Debra T Silverman, Stephen Chanock, Francisco X. Real, Núria Malats

Eur Urol. Author manuscript; available in PMC 2011 Nov 18.

Published in final edited form as: Eur Urol. 2010 Feb; 57(2): 283–292. Published online 2009 Aug 12. doi: 10.1016/j.eururo.2009.08.001

PMCID:: PMC3220186

Abstract Article PDF–595K

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 272285716.

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway

H.Dean Hosgood, III, Idan Menashe, Min Shen, Meredith Yeager, Jeff Yuenger, Preetha Rajaraman, Xingzhou He, Nilanjan Chatterjee, Neil E. Caporaso, Yong Zhu, Stephen J. Chanock, Tongzhang Zheng, Qing Lan

Carcinogenesis. 2008 Oct; 29(10): 1938–1943. Published online 2008 Aug 1. doi: 10.1093/carcin/bgn178

PMCID:: PMC2722857

Abstract Article PDF–181K

Select item 266678117.

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China

Min Shen, Roel Vermeulen, Preetha Rajaraman, Idan Menashe, Xingzhou He, Robert S. Chapman, Meredith Yeager, Gilles Thomas, Laurie Burdett, Amy Hutchinson, Jeff Yuenger, Stephen Chanock, Qing Lan

Environ Mol Mutagen. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Environ Mol Mutagen. 2009 May; 50(4): 285–290. doi: 10.1002/em.20452