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Select item 106618261.

A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity

Kristian Assing, Sofie E. Jørgensen, Katrine S. Sandgaard, Kerstin De Keukeleere, Marie B.-Hansen, Mikkel S. Petersen, Ulla B. Hartling, Thanis M. K.-de Vaal, Christian Nielsen, Marianne A. Jakobsen, Eleanor Watt, Stuart Adams, Qin Hao, Christina Fagerberg, Trine H. Mogensen

J Clin Immunol. 2023; 43(8): 1927–1940. Published online 2023 Aug 15. doi: 10.1007/s10875-023-01561-0

PMCID:: PMC10661826

Abstract Article PDF–4.5M

Select item 103232522.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 102972133.

Spatiotemporal Coordination of Rac1 and Cdc42 at the Whole Cell Level during Cell Ruffling

Siarhei Hladyshau, Jorik P. Stoop, Kosei Kamada, Shuyi Nie, Denis Tsygankov

Cells. 2023 Jun; 12(12): 1638. Published online 2023 Jun 15. doi: 10.3390/cells12121638

PMCID:: PMC10297213

Abstract Article PDF–7.7M

Select item 102841174.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 102799135.

AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity

Mario Ruiz, Ranjan Devkota, Delaney Kaper, Hanna Ruhanen, Kiran Busayavalasa, Uroš Radović, Marcus Henricsson, Reijo Käkelä, Jan Borén, Marc Pilon

J Biol Chem. 2023 Jun; 299(6): 104799. Published online 2023 May 8. doi: 10.1016/j.jbc.2023.104799

PMCID:: PMC10279913

Abstract Article PDF–4.1M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102131177.

Rbpj deficiency disrupts vascular remodeling via abnormal Apelin and Cdc42 activity in brain arteriovenous malformation

Subhodip Adhicary, Kayleigh Fanelli, Sera Nakisli, Brittney Ward, Isaac Pearce, Corinne M. Nielsen

Stroke. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Stroke. 2023 Jun; 54(6): 1593–1605. Published online 2023 Apr 13. doi: 10.1161/STROKEAHA.122.041853

PMCID:: PMC10213117

Abstract Article PDF–1.4M

Select item 101916268.

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

Katarzyna Bogucka-Janczi, Gregory Harms, Marie-May Coissieux, Mohamed Bentires-Alj, Bernd Thiede, Krishnaraj Rajalingam

eLife. 2023; 12: e85167. Published online 2023 Apr 14. doi: 10.7554/eLife.85167

PMCID:: PMC10191626

Abstract Article PDF–30M

Select item 101522379.

circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma

Xiang Li, Chenxing Wang, Hang Zhang, Yangjie Li, Deqiang Hou, Dingshan Liu, Rongyao Xu, Jie Cheng, Laikui Liu, Yu Fu, Jinhai Ye, Hongbing Jiang

Cancer Res. 2023 May 2; 83(9): 1459–1475. Published online 2023 Feb 22. doi: 10.1158/0008-5472.CAN-22-2585

PMCID:: PMC10152237

Abstract Article PDF–22M

Select item 1009264310.

BAG6 supports stress fiber formation by preventing the ubiquitin-mediated degradation of RhoA

Maho Miyauchi, Reina Matsumura, Hiroyuki Kawahara

Mol Biol Cell. 2023 Apr 1; 34(4): ar34. Published online 2023 Mar 17. doi: 10.1091/mbc.E22-08-0355

PMCID:: PMC10092643

Abstract Article PDF–23M

Select item 1005340311.

Git1-PGK1 interaction achieves self-protection against spinal cord ischemia-reperfusion injury by modulating Keap1/Nrf2 signaling

Tao Xu, Peng Gao, Yifan Huang, Mengyuan Wu, Jiang Yi, Zheng Zhou, Xuan Zhao, Tao Jiang, Hao Liu, Tao Qin, Zhenqi Yang, Xiaowei Wang, Tianyi Bao, Jian Chen, Shujie Zhao, Guoyong Yin

Redox Biol. 2023 Jun; 62: 102682. Published online 2023 Mar 20. doi: 10.1016/j.redox.2023.102682

PMCID:: PMC10053403

Abstract Article PDF–12M

Select item 1001453512.

“From molecular to clinic”: The pivotal role of CDC42 in pathophysiology of human papilloma virus related cancers and a correlated sensitivity of afatinib

Erdong Wei, Jiahua Li, Philipp Anand, Lars E. French, Adam Wattad, Benjamin Clanner-Engelshofen, Markus Reinholz

Front Immunol. 2023; 14: 1118458. Published online 2023 Mar 1. doi: 10.3389/fimmu.2023.1118458

PMCID:: PMC10014535

Abstract Article PDF–26M

Select item 999304213.

Polo-like kinase 1 promotes Cdc42-induced actin polymerization for asymmetric division in oocytes

Wai Shan Yuen, Qing Hua Zhang, Anne Bourdais, Deepak Adhikari, Guillaume Halet, John Carroll

Open Biol. 2023 Mar; 13(3): 220326. Published online March 8, 2023. doi: 10.1098/rsob.220326

PMCID:: PMC9993042

Abstract Article PDF–2.3M

Select item 997863514.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 995044715.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x