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Select item 107483741.

IFITM1 and IFITM3 Proteins Inhibit the Infectivity of Progeny HIV-1 without Disrupting Envelope Glycoprotein Clusters

Smita Verma, Yen-Cheng Chen, Mariana Marin, Scott E. Gillespie, Gregory B. Melikyan

Viruses. 2023 Dec; 15(12): 2390. Published online 2023 Dec 7. doi: 10.3390/v15122390

PMCID:: PMC10748374

Abstract Article PDF–2.9M

Select item 97427472.

Toll-like receptor 3 signaling induces interferon-induced transmembrane protein 1 in BEAS-2B cells

Masaki Dobashi, Toshihiro Shiratori, Tadaatsu Imaizumi, Shun Hashimoto, Shogo Kawaguchi, Kazuhiko Seya, Sadatomo Tasaka

Exp Biol Med (Maywood) 2022 Nov; 247(21): 1917–1922. Published online 2022 Sep 12. doi: 10.1177/15353702221121609

PMCID:: PMC9742747

Abstract Article PDF–1.1M

Select item 96291213.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 94227794.

Differential Leukocyte Expression of IFITM1 and IFITM3 in Patients with Severe Pandemic Influenza A(H1N1) and COVID-19

Nora E. Regino-Zamarripa, Gustavo Ramírez-Martínez, Luis Armando Jiménez-Álvarez, Alfredo Cruz-Lagunas, Itzel Alejandra Gómez-García, Sergio Ignacio-Cortés, José Eduardo Márquez-García, Lynette Miroslava Pacheco-Hernández, Jazmín Ariadna Ramírez-Noyola, Rodrigo Barquera, Criselda Mendoza-Milla, Cesar Luna-Rivero, José Guillermo Domínguez-Cherit, Remedios Ramírez-Rangel, Tatiana Sofía Rodríguez-Reyna, Carmen M. Hernández-Cárdenas, José Alberto Choreño-Parra, Gloria León-Ávila, Joaquín Zúñiga

J Interferon Cytokine Res. August 2022; 42(8): 430–443. Published online 2022 Aug 18. doi: 10.1089/jir.2022.0036

PMCID:: PMC9422779

Abstract Article PDF–1.1M

Select item 94056015.

Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer

Maria Gómez-Herranz, Jakub Faktor, Marcos Yébenes Mayordomo, Magdalena Pilch, Marta Nekulova, Lenka Hernychova, Kathryn L. Ball, Borivoj Vojtesek, Ted R. Hupp, Sachin Kote

Biomolecules. 2022 Aug; 12(8): 1090. Published online 2022 Aug 8. doi: 10.3390/biom12081090

PMCID:: PMC9405601

Abstract Article PDF–2.8M

Select item 93383136.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 86894607.

Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposi’s Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell-Specific Manner

Bojan F. Hörnich, Anna K. Großkopf, Candice J. Dcosta, Sarah Schlagowski, Alexander S. Hahn

mBio. 2021 Nov-Dec; 12(6): e02113-21. Published online 2021 Dec 21. doi: 10.1128/mBio.02113-21

PMCID:: PMC8689460

Abstract Article PDF–3.7M

Select item 85581708.

IFITM1 expression determines extracellular vesicle uptake in colorectal cancer

Andrea Kelemen, Idan Carmi, Ádám Oszvald, Péter Lőrincz, Gábor Petővári, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Zoltán Wiener

Cell Mol Life Sci. 2021 Nov; 78(21-22): 7009–7024. Published online 2021 Oct 5. doi: 10.1007/s00018-021-03949-w

PMCID:: PMC8558170

Abstract Article PDF–7.0M

Select item 85529079.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 851185610.

Lessons in self-defence: inhibition of virus entry by intrinsic immunity

Saliha Majdoul, Alex A. Compton

Nat Rev Immunol. 2022; 22(6): 339–352. Published online 2021 Oct 13. doi: 10.1038/s41577-021-00626-8

PMCID:: PMC8511856

Abstract Article PDF–3.2M

Select item 847552411.

IFITM Proteins That Restrict the Early Stages of Respiratory Virus Infection Do Not Influence Late-Stage Replication

Tina Meischel, Svenja Fritzlar, Fernando Villalon-Letelier, Melkamu B. Tessema, Andrew G. Brooks, Patrick C. Reading, Sarah L. Londrigan

J Virol. 2021 Oct; 95(20): e00837-21. Prepublished online 2021 Jul 28. Published online 2021 Sep 27. doi: 10.1128/JVI.00837-21

PMCID:: PMC8475524

Abstract Article PDF–3.5M

Select item 831920912.

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro

Caterina Prelli Bozzo, Rayhane Nchioua, Meta Volcic, Lennart Koepke, Jana Krüger, Desiree Schütz, Sandra Heller, Christina M. Stürzel, Dorota Kmiec, Carina Conzelmann, Janis Müller, Fabian Zech, Elisabeth Braun, Rüdiger Groß, Lukas Wettstein, Tatjana Weil, Johanna Weiß, Federica Diofano, Armando A. Rodríguez Alfonso, Sebastian Wiese, Daniel Sauter, Jan Münch, Christine Goffinet, Alberto Catanese, Michael Schön, Tobias M. Boeckers, Steffen Stenger, Kei Sato, Steffen Just, Alexander Kleger, Konstantin M. J. Sparrer, Frank Kirchhoff

Nat Commun. 2021; 12: 4584. Published online 2021 Jul 28. doi: 10.1038/s41467-021-24817-y

PMCID:: PMC8319209

Abstract Article PDF–5.0M

Select item 822101713.

Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression

Olivia K. Provance, Eric S. Geanes, Asona J. Lui, Anuradha Roy, Sean Holloran, Sumedha Gunewardena, Christy Hagan, Scott Weir, Joan Lewis-Wambi

Cancer Lett. Author manuscript; available in PMC 2022 Aug 28.

Published in final edited form as: Cancer Lett. 2021 Aug 28; 514: 12–29. Published online 2021 May 20. doi: 10.1016/j.canlet.2021.05.006

PMCID:: PMC8221017

Abstract Article PDF–4.4M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 774486515.

Opposing activities of IFITM proteins in SARS‐CoV‐2 infection

Guoli Shi, Adam D Kenney, Elena Kudryashova, Ashley Zani, Lizhi Zhang, Kin Kui Lai, Luanne Hall‐Stoodley, Richard T Robinson, Dmitri S Kudryashov, Alex A Compton, Jacob S Yount

EMBO J. 2021 Feb 1; 40(3): e106501. Published online 2020 Dec 21. doi: 10.15252/embj.2020106501

PMCID:: PMC7744865

Abstract Article PDF–2.2M

Select item 740404816.

Interferon-Induced Transmembrane Protein 1 (IFITM1) Promotes Distant Metastasis of Small Cell Lung Cancer

Shuichi Sakamoto, Hiroyuki Inoue, Yasuko Kohda, Shun-ichi Ohba, Taketoshi Mizutani, Manabu Kawada

Int J Mol Sci. 2020 Jul; 21(14): 4934. Published online 2020 Jul 13. doi: 10.3390/ijms21144934

PMCID:: PMC7404048

Abstract Article PDF–3.0M

Select item 715085317.

Topology, Antiviral Functional Residues and Mechanism of IFITM1

Fang Sun, Zhiqiang Xia, Yuewen Han, Minjun Gao, Luyao Wang, Yingliang Wu, Jean-Marc Sabatier, Lixia Miao, Zhijian Cao

Viruses. 2020 Mar; 12(3): 295. Published online 2020 Mar 8. doi: 10.3390/v12030295

PMCID:: PMC7150853

Abstract Article PDF–3.3M

Select item 712621318.

Identification of the polymorphisms in IFITM1 gene and their association in a Korean population with ulcerative colitis

Ji-Su Mo, Kyung-Sook Na, Ji-In Yu, Soo-Cheon Chae

Immunol Lett. 2013 November-December; 156(1): 118–122. Published online 2013 Oct 10. doi: 10.1016/j.imlet.2013.09.026

PMCID:: PMC7126213

Abstract Article PDF–775K

Select item 711128419.

The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis

Maria Gómez-Herranz, Marta Nekulova, Jakub Faktor, Lenka Hernychova, Sachin Kote, Elizabeth H. Sinclair, Rudolf Nenutil, Borivoj Vojtesek, Kathryn L. Ball, Ted R. Hupp

Cell Signal. 2019 Aug; 60: 39–56. Published online 2019 Apr 2. doi: 10.1016/j.cellsig.2019.03.024

PMCID:: PMC7111284

Abstract Article PDF–5.0M

Select item 711071220.

Characteristics of IFITM, the newly identified IFN-inducible anti-HIV-1 family proteins

Nopporn Chutiwitoonchai, Masateru Hiyoshi, Yuka Hiyoshi-Yoshidomi, Michihiro Hashimoto, Kenzo Tokunaga, Shinya Suzu

Microbes Infect. 2013 Apr; 15(4): 280–290. Published online 2013 Jan 30. doi: 10.1016/j.micinf.2012.12.003

PMCID:: PMC7110712

Abstract Article PDF–1.1M

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