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Select item 101085911.

The T-type calcium channel Ca_V3.2 regulates bladder afferent responses to mechanical stimuli

Luke Grundy, Cindy Tay, Stewart Christie, Andrea M. Harrington, Joel Castro, Fernanda C. Cardoso, Richard J. Lewis, Vladimir Zagorodnyuk, Stuart M. Brierley

Pain. 2023 May; 164(5): 1012–1026. Published online 2022 Oct 21. doi: 10.1097/j.pain.0000000000002795

PMCID:: PMC10108591

Abstract Article PDF–2.7M

Select item 97701502.

Blocking MG53^S255 Phosphorylation Protects Diabetic Heart From Ischemic Injury

Fengxiang Lv, Yingfan Wang, Dan Shan, Sile Guo, Gengjia Chen, Li Jin, Wen Zheng, Han Feng, Xiaohu Zeng, Shuo Zhang, Yan Zhang, Xinli Hu, Rui-Ping Xiao

Circ Res. 2022 Dec 2; 131(12): 962–976. Published online 2022 Nov 7. doi: 10.1161/CIRCRESAHA.122.321055

PMCID:: PMC9770150

Abstract Article PDF–7.3M

Select item 95502573.

Ubiquitin-like protein FAT10 promotes renal fibrosis by stabilizing USP7 to prolong CHK1-mediated G2/M arrest in renal tubular epithelial cells

Ying Shao, Wenming Zhang, Dongnian Du, Yi Yu, Qing Li, Xiaogang Peng

Aging (Albany NY) 2022 Sep 29; 14(18): 7527–7546. Published online 2022 Sep 22. doi: 10.18632/aging.204301

PMCID:: PMC9550257

Abstract Article PDF–2.6M

Select item 91179294.

Caveolin-3 prevents swelling-induced membrane damage via regulation of I_Cl,swell activity

Daniel G.P. Turner, Leonid Tyan, Frank C. DeGuire, Roman Y. Medvedev, Sami J. Stroebel, Di Lang, Alexey V. Glukhov

Biophys J. 2022 May 3; 121(9): 1643–1659. Published online 2022 Apr 2. doi: 10.1016/j.bpj.2022.04.001

PMCID:: PMC9117929

Abstract Article PDF–3.5M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76993136.

A Role for Caveolin-3 in the Pathogenesis of Muscular Dystrophies

Bhola Shankar Pradhan, Tomasz J. Prószyński

Int J Mol Sci. 2020 Nov; 21(22): 8736. Published online 2020 Nov 19. doi: 10.3390/ijms21228736

PMCID:: PMC7699313

Abstract Article PDF–875K

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67632428.

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development

Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong

J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107

PMCID:: PMC6763242

Abstract Article PDF–12M

Select item 64885999.

Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells

Melissa Dewulf, Darius Vasco Köster, Bidisha Sinha, Christine Viaris de Lesegno, Valérie Chambon, Anne Bigot, Mona Bensalah, Elisa Negroni, Nicolas Tardif, Joanna Podkalicka, Ludger Johannes, Pierre Nassoy, Gillian Butler-Browne, Christophe Lamaze, Cedric M. Blouin

Nat Commun. 2019; 10: 1974. Published online 2019 Apr 29. doi: 10.1038/s41467-019-09405-5

PMCID:: PMC6488599

Abstract Article PDF–3.9M

Select item 641875110.

Long QT syndrome caveolin‐3 mutations differentially modulate K_v4 and Ca_v1.2 channels to contribute to action potential prolongation

Leonid Tyan, Jason D. Foell, Kevin P. Vincent, Marites T. Woon, Walatta T. Mesquitta, Di Lang, Jabe M. Best, Michael J. Ackerman, Andrew D. McCulloch, Alexey V. Glukhov, Ravi C. Balijepalli, Timothy J. Kamp

J Physiol. 2019 Mar 15; 597(6): 1531–1551. Published online 2019 Jan 24. doi: 10.1113/JP276014

PMCID:: PMC6418751

Abstract Article PDF–2.4M

Select item 585251811.

The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability

Giulia Campostrini, Mattia Bonzanni, Alessio Lissoni, Claudia Bazzini, Raffaella Milanesi, Elena Vezzoli, Maura Francolini, Mirko Baruscotti, Annalisa Bucchi, Ilaria Rivolta, Matteo Fantini, Stefano Severi, Riccardo Cappato, Lia Crotti, Peter J. Schwartz, Dario DiFrancesco, Andrea Barbuti

Cardiovasc Res. 2017 Aug; 113(10): 1256–1265. Published online 2017 Jun 21. doi: 10.1093/cvr/cvx122

PMCID:: PMC5852518

Abstract Article PDF–540K

Select item 577142012.

Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain-Specific Interaction: Implications for Purkinje cell-Dependent Ventricular Arrhythmias

Ravi Vaidyanathan, Hanora Van Ert, Kazi T Haq, Stefano Morotti, Samuel Esch, Elise C. McCune, Eleonora Grandi, Lee L. Eckhardt

Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2018 Jan; 11(1): e005800. doi: 10.1161/CIRCEP.117.005800

PMCID:: PMC5771420

Abstract Article PDF–1.1M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 537173014.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 524859815.

The Caveolin‐3 G56S sequence variant of unknown significance: Muscle biopsy findings and functional cell biological analysis

Eva Brauers, Andreas Roos, Laxmikanth Kollipara, René P. Zahedi, Alf Beckmann, Nilane Mohanadas, Hartmut Bauer, Martin Häusler, Stéphanie Thoma, Wolfram Kress, Jan Senderek, Joachim Weis

Proteomics Clin Appl. 2017 Jan; 11(1-2): 1600007. Published online 2016 Nov 14. doi: 10.1002/prca.201600007

PMCID:: PMC5248598

Abstract Article PDF–2.0M

Select item 520717316.

MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle

Hyun Lee, Jung-Jin Park, Nga Nguyen, Jun Sub Park, Jin Hong, Seung-Hyeob Kim, Woon Young Song, Hak Joong Kim, Kwangman Choi, Sungchan Cho, Jae-Seon Lee, Bong-Woo Kim, Young-Gyu Ko

J Biol Chem. 2016 Dec 23; 291(52): 26627–26635. Published online 2016 Nov 3. doi: 10.1074/jbc.M116.754424

PMCID:: PMC5207173

Abstract Article PDF–1.9M

Select item 490637917.

A pH-Mediated Topological Switch within the N-Terminal Domain of Human Caveolin-3

Ji-Hun Kim, Jonathan P. Schlebach, Zhenwei Lu, Dungeng Peng, Kaitlyn C. Reasoner, Charles R. Sanders

Biophys J. 2016 Jun 7; 110(11): 2475–2485. Published online 2016 Jun 7. doi: 10.1016/j.bpj.2016.05.004

PMCID:: PMC4906379

Abstract Article PDF–1.9M

Select item 476696818.

Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles

Jonathan P. Schlebach, Paul J. Barrett, Charles A. Day, Ji Hun Kim, Anne K. Kenworthy, Charles R. Sanders

Biochemistry. 2016 Feb 23; 55(7): 985–988. Published online 2016 Feb 9. doi: 10.1021/acs.biochem.5b01154

PMCID:: PMC4766968

Abstract Article PDF–2.1M

Select item 447252419.

MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line

Fiorella Faggi, Silvia Codenotti, Pietro Luigi Poliani, Manuela Cominelli, Nicola Chiarelli, Marina Colombi, Marika Vezzoli, Eugenio Monti, Federica Bono, Giovanni Tulipano, Chiara Fiorentini, Alessandra Zanola, Harriet P. Lo, Robert G. Parton, Charles Keller, Alessandro Fanzani

PLoS One. 2015; 10(6): e0130287. Published online 2015 Jun 18. doi: 10.1371/journal.pone.0130287

PMCID:: PMC4472524

Abstract Article PDF–14M

Select item 434997520.

New Host Factors Important for Respiratory Syncytial Virus (RSV) Replication Revealed by a Novel Microfluidics Screen for Interactors of Matrix (M) Protein

Sarit Kipper, Samar Hamad, Leon Caly, Dorit Avrahami, Eran Bacharach, David A. Jans, Doron Gerber, Monika Bajorek

Mol Cell Proteomics. 2015 Mar; 14(3): 532–543. Published online 2015 Jan 2. doi: 10.1074/mcp.M114.044107

PMCID:: PMC4349975

Abstract Article PDF–1.8M

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