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Select item 111617321.

RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells

Nour Sfeir, Marilyn Kajdan, Stéphan Jalaguier, Sandrine Bonnet, Catherine Teyssier, Samuel Pyrdziak, Rong Yuan, Emilie Bousquet, Antonio Maraver, Florence Bernex, Nelly Pirot, Florence Boissière‐Michot, Audrey Castet‐Nicolas, Marion Lapierre, Vincent Cavaillès

Mol Oncol. 2024 Jun; 18(6): 1510–1530. Published online 2024 Mar 8. doi: 10.1002/1878-0261.13626

PMCID:: PMC11161732

Abstract Article PDF–6.3M

Select item 109871502.

LINC MIR503HG Controls SC‐β Cell Differentiation and Insulin Production by Targeting CDH1 and HES1

Yang Xu, Susu Mao, Haowen Fan, Jian Wan, Lin Wang, Mingyu Zhang, Shajun Zhu, Jin Yuan, Yuhua Lu, Zhiwei Wang, Bin Yu, Zhaoyan Jiang, Yan Huang

Adv Sci (Weinh) 2024 Apr; 11(13): 2305631. Published online 2024 Jan 20. doi: 10.1002/advs.202305631

PMCID:: PMC10987150

Abstract Article PDF–9.3M

Select item 105849043.

MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1

Chen Zhang, Weilong Ye, Mengyao Zhao, Lujue Long, Dengsheng Xia, Zhipeng Fan

Int J Oral Sci. 2023; 15: 48. Published online 2023 Oct 18. doi: 10.1038/s41368-023-00253-0

PMCID:: PMC10584904

Abstract Article PDF–7.9M

Select item 105199924.

Loss of HES1 expression is associated with extracellular matrix remodeling and tumor immune suppression in KRAS mutant colon adenocarcinomas

Lei Wang, Wenchao Gu, Bingqing Zou, Matthew Kalady, Wei Xin, Lan Zhou

Sci Rep. 2023; 13: 15999. Published online 2023 Sep 25. doi: 10.1038/s41598-023-42234-7

PMCID:: PMC10519992

Abstract Article PDF–8.6M

Select item 102384195.

NOTCH4^ΔL12_16 sensitizes lung adenocarcinomas to EGFR-TKIs through transcriptional down-regulation of HES1

Bin Zhang, Shaowei Dong, Jian Wang, Tuxiong Huang, Pan Zhao, Jing Xu, Dongcheng Liu, Li Fu, Lingwei Wang, Guangsuo Wang, Chang Zou

Nat Commun. 2023; 14: 3183. Published online 2023 Jun 2. doi: 10.1038/s41467-023-38833-7

PMCID:: PMC10238419

Abstract Article PDF–5.5M

Select item 95808816.

Identification and targeting of a HES1‐YAP1‐CDKN1C functional interaction in fusion‐negative rhabdomyosarcoma

Alexander R. Kovach, Kristianne M. Oristian, David G. Kirsch, Rex C. Bentley, Changde Cheng, Xiang Chen, Po‐Han Chen, Jen‐Tsan Ashley Chi, Corinne M. Linardic

Mol Oncol. 2022 Oct; 16(20): 3587–3605. Published online 2022 Aug 29. doi: 10.1002/1878-0261.13304

PMCID:: PMC9580881

Abstract Article PDF–2.3M

Select item 93796857.

Induction of Transcriptional Inhibitor HES1 and the Related Repression of Tumor-Suppressor TXNIP Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase NPM-ALK

Qian Zhang, Hong Y. Wang, Anindita Nayak, Selene Nunez-Cruz, Artur Slupianek, Xiaobin Liu, Johnvesly Basappa, Jing-Song Fan, Seble Chekol, Reza Nejati, Agata M. Bogusz, Suzanne D. Turner, Kunchithapadam Swaminathan, Mariusz A. Wasik

Am J Pathol. 2022 Aug; 192(8): 1186–1198. doi: 10.1016/j.ajpath.2022.05.005

PMCID:: PMC9379685

Abstract Article PDF–2.1M

Select item 88508948.

LGR5, HES1 and ATOH1 in Young Rectal Cancer Patients in Egyptian

Heba Morsy, Ahmed Gaballah, Mohamed Samir, Vandrome Nakundi, Mohamed Shamseya, Hanan Mahrous, Abeer Ghazal, Mervat Hashish, Waleed Arafat

Asian Pac J Cancer Prev. 2021 Sep; 22(9): 2819–2830. doi: 10.31557/APJCP.2021.22.9.2819

PMCID:: PMC8850894

Abstract Article PDF–596K

Select item 86093269.

Differential phase register of Hes1 oscillations with mitoses underlies cell-cycle heterogeneity in ER⁺ breast cancer cells

Nitin Sabherwal, Andrew Rowntree, Elli Marinopoulou, Tom Pettini, Sean Hourihane, Riba Thomas, Ximena Soto, Jochen Kursawe, Nancy Papalopulu

Proc Natl Acad Sci U S A. 2021 Nov 9; 118(45): e2113527118. Published online 2021 Nov 1. doi: 10.1073/pnas.2113527118

PMCID:: PMC8609326

Abstract Article PDF–2.7M

Select item 860163210.

Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity

Floris Leenders, Nathalie Groen, Natascha de Graaf, Marten A. Engelse, Ton J. Rabelink, Eelco J. P. de Koning, Françoise Carlotti

Front Immunol. 2021; 12: 690379. Published online 2021 Nov 4. doi: 10.3389/fimmu.2021.690379

PMCID:: PMC8601632

Abstract Article PDF–14M

Select item 832985011.

ILC2 Cells Promote Th2 Cell Differentiation in AECOPD Through Activated Notch-GATA3 Signaling Pathway

Min Jiang, Ren Cai, Jing Wang, Zheng Li, Dan Xu, Jing Jing, Fengbo Zhang, Fengsen Li, Jianbing Ding

Front Immunol. 2021; 12: 685400. Published online 2021 Jun 18. doi: 10.3389/fimmu.2021.685400

PMCID:: PMC8329850

Abstract Article PDF–1.4M

Select item 828108512.

Sirt3 promotes the autophagy of HK-2 human proximal tubular epithelial cells via the inhibition of Notch-1/Hes-1 signaling

Ying Wang, Jiang Chang, Zi-Qiang Wang, Ying Li

Mol Med Rep. 2021 Sep; 24(3): 634. Published online 2021 Jul 6. doi: 10.3892/mmr.2021.12273

PMCID:: PMC8281085

Abstract Article PDF–3.2M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 800904814.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 777624115.

HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development

Matthias De Decker, Marieke Lavaert, Juliette Roels, Laurentijn Tilleman, Bart Vandekerckhove, Georges Leclercq, Filip Van Nieuwerburgh, Pieter Van Vlierberghe, Tom Taghon

Haematologica. 2021 Jan 1; 106(1): 130–141. Published online 2020 Jan 9. doi: 10.3324/haematol.2019.226126

PMCID:: PMC7776241

Abstract Article PDF–3.2M

Select item 775703716.

HES1 promotes breast cancer stem cells by elevating Slug in triple-negative breast cancer

Xiaoying Li, Yang Li, Xianqiang Du, Xu Wang, Shu Guan, Yu Cao, Feng Jin, Feng Li

Int J Biol Sci. 2021; 17(1): 247–258. Published online 2021 Jan 1. doi: 10.7150/ijbs.53477

PMCID:: PMC7757037

Abstract Article PDF–2.2M

Select item 751779817.

microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis

Dong Yang, Tianyang Xu, Lin Fan, Kaiyuan Liu, Guodong Li

J Exp Clin Cancer Res. 2020; 39: 201. Published online 2020 Sep 24. doi: 10.1186/s13046-020-01670-3

Correction in:: J Exp Clin Cancer Res. 2021; 40: 17.

PMCID:: PMC7517798

Abstract Article PDF–1.8M

Select item 659891018.

Human cytomegalovirus infection dysregulates neural progenitor cell fate by disrupting Hes1 rhythm and down-regulating its expression

Xi-Juan Liu, Xuan Jiang, Sheng-Nan Huang, Jin-Yan Sun, Fei Zhao, Wen-Bo Zeng, Min-Hua Luo

Virol Sin. 2017 Jun; 32(3): 188–198. Published online 2017 Apr 24. doi: 10.1007/s12250-017-3956-0

PMCID:: PMC6598910

Abstract Article PDF–1.0M

Select item 653659919.

Hypomethylation‐mediated activation of cancer/testis antigen KK‐LC‐1 facilitates hepatocellular carcinoma progression through activating the Notch1/Hes1 signalling

Zhiqiang Chen, Xueliang Zuo, Liyong Pu, Yao Zhang, Guoyong Han, Long Zhang, Zhengshan Wu, Wei You, Jianjie Qin, Xinzheng Dai, Hongbing Shen, Xuehao Wang, Jindao Wu

Cell Prolif. 2019 May; 52(3): e12581. Published online 2019 Mar 20. doi: 10.1111/cpr.12581

PMCID:: PMC6536599

Abstract Article PDF–4.8M

Select item 642652420.

HES1 Protein Modulates Human Papillomavirus–Mediated Carcinoma of the Uterine Cervix

Richa Tripathi, Gayatri Rath, Vishwas Sharma, Showket Hussain, Shashi Sharma, Mausumi Bharadwaj, Ravi Mehrotra

J Glob Oncol. 2019; 5: JGO.18.00141. Published online 2019 Jan 7. doi: 10.1200/JGO.18.00141

PMCID:: PMC6426524

Abstract Article PDF–1.1M

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