PMC Links for GEO Profiles (Select 131524783) - PMC

Select item 110871271.

Biological significance of METTL5 in atherosclerosis: comprehensive analysis of single-cell and bulk RNA sequencing data

Jianjin Wu, Lei Wang, Shuaishuai Xi, Chao Ma, Fukang Zou, Guanyu Fang, Fangbing Liu, Xiaokai Wang, Lefeng Qu

Aging (Albany NY) 2024 Apr 30; 16(8): 7267–7276. Published online 2024 Apr 24. doi: 10.18632/aging.205755

PMCID:: PMC11087127

Abstract Article PDF–1.5M

Select item 110150542.

The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression

Qi Wang, Yuxi Huang, Yu Zhu, Wenlong Zhang, Binfeng Wang, Xuefeng Du, Qiqiang Dai, Fabiao Zhang, Zheping Fang

Cancer Med. 2024 Apr; 13(7): e7165. Published online 2024 Apr 12. doi: 10.1002/cam4.7165

PMCID:: PMC11015054

Abstract Article PDF–30M

Select item 100096683.

METTL5 stabilizes c‐Myc by facilitating USP5 translation to reprogram glucose metabolism and promote hepatocellular carcinoma progression

Peng Xia, Hao Zhang, Haofeng Lu, Kequan Xu, Xiang Jiang, Yuke Jiang, Xiangdong Gongye, Zhang Chen, Jie Liu, Xi Chen, Weijie Ma, Zhonglin Zhang, Yufeng Yuan

Cancer Commun (Lond) 2023 Mar; 43(3): 338–364. Published online 2023 Jan 5. doi: 10.1002/cac2.12403

PMCID:: PMC10009668

Abstract Article PDF–14M

Select item 89736374.

The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma

Xiaojuan Liu, Hui Ma, Lisha Ma, Kun Li, Yanhua Kang

Bioengineered. 2022; 13(3): 5525–5536. Published online 2022 Feb 15. doi: 10.1080/21655979.2022.2036912

PMCID:: PMC8973637

Abstract Article PDF–4.7M

Select item 88574815.

The METTL5-TRMT112 N⁶-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation

Caraline Sepich-Poore, Zhong Zheng, Emily Schmitt, Kailong Wen, Zijie Scott Zhang, Xiao-Long Cui, Qing Dai, Allen C. Zhu, Linda Zhang, Arantxa Sanchez Castillo, Haiyan Tan, Junmin Peng, Xiaoxi Zhuang, Chuan He, Sigrid Nachtergaele

J Biol Chem. 2022 Mar; 298(3): 101590. Published online 2022 Jan 14. doi: 10.1016/j.jbc.2022.101590

PMCID:: PMC8857481

Abstract Article PDF–2.3M

Select item 87086156.

Human TRMT112-Methyltransferase Network Consists of Seven Partners Interacting with a Common Co-Factor

Baiba Brūmele, Margit Mutso, Lilian Telanne, Kadri Õunap, Karīna Spunde, Aare Abroi, Reet Kurg

Int J Mol Sci. 2021 Dec; 22(24): 13593. Published online 2021 Dec 18. doi: 10.3390/ijms222413593

PMCID:: PMC8708615

Abstract Article PDF–2.7M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79488158.

Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima

Dan Yu, Gundeep Kaur, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng

J Biol Chem. 2021 Jan-Jun; 296: 100270. Published online 2021 Jan 9. doi: 10.1016/j.jbc.2021.100270

PMCID:: PMC7948815

Abstract Article PDF–1.8M

Select item 71973549.

The rRNA m⁶A methyltransferase METTL5 is involved in pluripotency and developmental programs

Valentina V. Ignatova, Paul Stolz, Steffen Kaiser, Tobias H. Gustafsson, Palma Rico Lastres, Adrián Sanz-Moreno, Yi-Li Cho, Oana V. Amarie, Antonio Aguilar-Pimentel, Tanja Klein-Rodewald, Julia Calzada-Wack, Lore Becker, Susan Marschall, Markus Kraiger, Lillian Garrett, Claudia Seisenberger, Sabine M. Hölter, Kayla Borland, Erik Van De Logt, Pascal W.T.C. Jansen, Marijke P. Baltissen, Magdalena Valenta, Michiel Vermeulen, Wolfgang Wurst, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabe de Angelis, Oliver J. Rando, Stefanie M. Kellner, Sebastian Bultmann, Robert Schneider

Genes Dev. 2020 May 1; 34(9-10): 715–729. doi: 10.1101/gad.333369.119

PMCID:: PMC7197354

Abstract Article PDF–3.8M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 681755911.

Bi-allelic Variants in METTL5 Cause Autosomal-Recessive Intellectual Disability and Microcephaly

Elodie M. Richard, Daniel L. Polla, Muhammad Zaman Assir, Minerva Contreras, Mohsin Shahzad, Asma A. Khan, Attia Razzaq, Javed Akram, Moazzam N. Tarar, Thomas A. Blanpied, Zubair M. Ahmed, Rami Abou Jamra, Dagmar Wieczorek, Hans van Bokhoven, Sheikh Riazuddin, Saima Riazuddin

Am J Hum Genet. 2019 Oct 3; 105(4): 869–878. Published online 2019 Sep 26. doi: 10.1016/j.ajhg.2019.09.007

PMCID:: PMC6817559

Abstract Article PDF–1.7M

Select item 673586512.

The human 18S rRNA m⁶A methyltransferase METTL5 is stabilized by TRMT112

Nhan van Tran, Felix G M Ernst, Ben R Hawley, Christiane Zorbas, Nathalie Ulryck, Philipp Hackert, Katherine E Bohnsack, Markus T Bohnsack, Samie R Jaffrey, Marc Graille, Denis L J Lafontaine

Nucleic Acids Res. 2019 Sep 5; 47(15): 7719–7733. Published online 2019 Jul 22. doi: 10.1093/nar/gkz619

PMCID:: PMC6735865

Abstract Article PDF–4.3M

Select item 503652713.

Panorama of ancient metazoan macromolecular complexes

Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Nature. Author manuscript; available in PMC 2016 Sep 26.

Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877

PMCID:: PMC5036527

Abstract Article PDF–4.7M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 52892815.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 31093416.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

Select item 13924117.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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