PMC Links for GEO Profiles (Select 131530162) - PMC

Johannes F Fahrmann, Amanda R Wasylishen, Carolina R C Pieterman, Ehsan Irajizad, Jody Vykoukal, Ranran Wu, Jennifer B Dennison, Christine B Peterson, Hua Zhao, Kim-Anh Do, Daniel M Halperin, Sunita K Agarwal, Jenny E Blau, Smita Jha, Jaydira Del Rivero, Naris Nilubol, Mary F Walter, James M Welch, Lee S Weinstein, Menno R Vriens, Rachel S van Leeuwaarde, Mark J C van Treijen, Gerlof D Valk, Nancy D Perrier, Samir M Hanash, Hiroyuki Katayama

J Clin Endocrinol Metab. 2023 Dec; 108(12): 3260–3271. Published online 2023 Jun 12. doi: 10.1210/clinem/dgad315

PMCID:: PMC11032251

Abstract Article

Select item 110149144.

Combined deletion of MEN1, ATRX and PTEN triggers development of high-grade pancreatic neuroendocrine tumors in mice

Mary Esmeralda Fuentes, Xiaoyin Lu, Natasha M. Flores, Simone Hausmann, Pawel K. Mazur

Sci Rep. 2024; 14: 8510. Published online 2024 Apr 12. doi: 10.1038/s41598-024-58874-2

PMCID:: PMC11014914

Abstract Article PDF–1.7M

Select item 106709865.

Dependency of B-Cell Acute Lymphoblastic Leukemia and Multiple Myeloma Cell Lines on MEN1 Extends beyond MEN1–KMT2A Interaction

Tatjana Magdalena Wolffhardt, Franz Ketzer, Stefano Telese, Thomas Wirth, Alexey Ushmorov

Int J Mol Sci. 2023 Nov; 24(22): 16472. Published online 2023 Nov 17. doi: 10.3390/ijms242216472

PMCID:: PMC10670986

Abstract Article PDF–6.1M

Select item 106524646.

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival

Ezgi Ozyerli-Goknar, Ezgi Yagmur Kala, Ali Cenk Aksu, Ipek Bulut, Ahmet Cingöz, Sheikh Nizamuddin, Martin Biniossek, Fidan Seker-Polat, Tunc Morova, Can Aztekin, Sonia H. Y. Kung, Hamzah Syed, Nurcan Tuncbag, Mehmet Gönen, Martin Philpott, Adam P. Cribbs, Ceyda Acilan, Nathan A. Lack, Tamer T. Onder, H. T. Marc Timmers, Tugba Bagci-Onder

Cell Commun Signal. 2023; 21: 328. Published online 2023 Nov 16. doi: 10.1186/s12964-023-01335-6

PMCID:: PMC10652464

Abstract Article PDF–8.0M

Select item 105886517.

Multiple endocrine neoplasia type 1 with Zollinger–Ellison syndrome: clinicopathological analysis of a Japanese family with focus on menin immunohistochemistry

Noriko Kimura, Yasuji Hirata, Nozomu Iwashiro, Hiroshi Kijima, Shinobu Takayasu, Satoshi Yamagata, Satoru Sakihara, Shinya Uchino, Masanori Ohara

Front Endocrinol (Lausanne) 2023; 14: 1221514. Published online 2023 Oct 6. doi: 10.3389/fendo.2023.1221514

PMCID:: PMC10588651

Abstract Article PDF–6.2M

Select item 104501998.

MEN1 is a regulator of alternative splicing and prevents R-loop-induced genome instability through suppression of RNA polymerase II elongation

Bangming Jin, Jiamei Zhu, Ting Pan, Yunqiao Yang, Li Liang, Yuxia Zhou, Tuo Zhang, Yin Teng, Ziming Wang, Xuyan Wang, Qianting Tian, Bing Guo, Haiyang Li, Tengxiang Chen

Nucleic Acids Res. 2023 Aug 25; 51(15): 7951–7971. Published online 2023 Jul 3. doi: 10.1093/nar/gkad548

PMCID:: PMC10450199

Abstract Article PDF–2.8M

Select item 103646439.

Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover

Suzann Duan, Sulaiman Sheriff, Uloma B. Elvis-Offiah, Brandon L. Witten, Travis W. Sawyer, Sinju Sundaresan, Tomasz Cierpicki, Jolanta Grembecka, Juanita L. Merchant

Cancer Res Commun. 2023 Jul; 3(7): 1318–1334. Published online 2023 Jul 24. doi: 10.1158/2767-9764.CRC-22-0522

PMCID:: PMC10364643

Abstract Article PDF–16M

Select item 1035814310.

Frequent Germ-Line Mutations of the MEN1, CASR, and HRPT2/CDC73 Genes in Young Patients with Clinically Non-familial Primary Hyperparathyroidism

Lee F. Starker, Tobias Åkerström, William D. Long, Alberto Delgado-Verdugo, Patricia Donovan, Robert Udelsman, Richard P. Lifton, Tobias Carling

Horm Cancer. 2012 Apr; 3(1-2): 44–51. Published online 2011 Dec 21. doi: 10.1007/s12672-011-0100-8

PMCID:: PMC10358143

Abstract Article PDF–296K

Select item 1034840211.

MEN1 PNET Genotype/Phenotype- Is there any advance on predicting or preventing?

Bhavishya Ramamoorthy, Naris Nilubol

Surg Oncol Clin N Am. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Surg Oncol Clin N Am. 2023 Apr; 32(2): 315–325. doi: 10.1016/j.soc.2022.10.008

PMCID:: PMC10348402

Article PDF–330K

Select item 1033798212.

Evaluating the role of MEN1 gene expression and its clinical significance in breast cancer patients

Sheersh Massey, Mohammad Aasif Khan, Safia Obaidur Rab, Saad Mustafa, Asifa Khan, Zoya Malik, Rahimunnisa Shaik, Mohit Kumar Verma, SVS Deo, Syed Akhtar Husain

PLoS One. 2023; 18(7): e0288482. Published online 2023 Jul 12. doi: 10.1371/journal.pone.0288482

PMCID:: PMC10337982

Abstract Article PDF–1.9M

Select item 1015789613.

MEN1 mutations mediate clinical resistance to Menin inhibition

Florian Perner, Eytan M. Stein, Daniela V. Wenge, Sukrit Singh, Jeonghyeon Kim, Athina Apazidis, Homa Rahnamoun, Disha Anand, Christian Marinaccio, Charlie Hatton, Yanhe Wen, Richard M. Stone, David Schaller, Shoron Mowla, Wenbin Xiao, Holly A. Gamlen, Aaron J. Stonestrom, Sonali Persaud, Elizabeth Ener, Jevon A. Cutler, John G. Doench, Gerard M. McGeehan, Andrea Volkamer, John D. Chodera, Radosław P. Nowak, Eric S. Fischer, Ross L. Levine, Scott A. Armstrong, Sheng F. Cai

Nature. Author manuscript; available in PMC 2023 Sep 15.

Published in final edited form as: Nature. 2023 Mar; 615(7954): 913–919. Published online 2023 Mar 15. doi: 10.1038/s41586-023-05755-9

PMCID:: PMC10157896

Abstract Article PDF–4.2M

Select item 1006958414.

ANXA1-derived peptide for targeting PD-L1 degradation inhibits tumor immune evasion in multiple cancers

Zheng-Zheng Yu, Yun-Ya Liu, Wei Zhu, Ding Xiao, Wei Huang, Shan-Shan Lu, Hong Yi, Ting Zeng, Xue-Ping Feng, Li Yuan, Jie-Ya Qiu, Di Wu, Qi Wen, Jian-Hua Zhou, Wei Zhuang, Zhi-Qiang Xiao

J Immunother Cancer. 2023; 11(3): e006345. Published online 2023 Mar 31. doi: 10.1136/jitc-2022-006345

PMCID:: PMC10069584

Abstract Article PDF–11M

Select item 997887815.

Казуистические случаи карциномы околощитовидной железы при верифицированной мутации в гене <i>MEN1</i>

С. В. Пылина, Е. И. Ким, Е. В. Бондаренко, Ю. А. Крупинова, А. К. Еремкина, Н. Г. Мокрышева

Probl Endokrinol (Mosk) 2023; 69(1): 15–27. Russian. Published online 2023 Feb 25. doi: 10.14341/probl13176

PMCID:: PMC9978878

Abstract Article PDF–5.6M

Select item 982828916.

MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors: MEN1 promotes ferroptosis in pancreatic neuroendocrine tumors

Zeng Ye, Haidi Chen, Shunrong Ji, Yuheng Hu, Xin Lou, Wuhu Zhang, Desheng Jing, Guixiong Fan, Yue Zhang, Xuemin Chen, Qifeng Zhuo, Jie Chen, Xiaowu Xu, Xianjun Yu, Jin Xu, Yi Qin, Heli Gao

Acta Biochim Biophys Sin (Shanghai) 2022 Nov; 54(11): 1599–1609. Published online 2022 Nov 8. doi: 10.3724/abbs.2022162

PMCID:: PMC9828289

Abstract Article PDF–2.3M

Select item 954034517.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 937715218.

Loss of MEN1 leads to renal fibrosis and decreases HGF‐Adamts5 pathway activity via an epigenetic mechanism

Bangming Jin, Jiamei Zhu, Yuxia Zhou, Li Liang, Yunqiao Yang, Lifen Xu, Tuo Zhang, Po Li, Ting Pan, Bing Guo, Tengxiang Chen, Haiyang Li

Clin Transl Med. 2022 Aug; 12(8): e982. Published online 2022 Aug 15. doi: 10.1002/ctm2.982

PMCID:: PMC9377152

Abstract Article PDF–21M

Select item 936153519.

Multi-omics analyses of MEN1 missense mutations identify disruption of menin–MLL and menin–JunD interactions as critical requirements for molecular pathogenicity

Koen M. A. Dreijerink, Ezgi Ozyerli-Goknar, Stefanie Koidl, Ewoud J. van der Lelij, Priscilla van den Heuvel, Jeffrey J. Kooijman, Martin L. Biniossek, Kees W. Rodenburg, Sheikh Nizamuddin, H. T. Marc Timmers

Epigenetics Chromatin. 2022; 15: 29. Published online 2022 Aug 9. doi: 10.1186/s13072-022-00461-8

PMCID:: PMC9361535

Abstract Article PDF–5.7M

Select item 929024120.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

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