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Select item 106897881.

Unravelling transcriptomic complexity in breast cancer through modulation of DARPP-32 expression and signalling pathways

Behnaz Saidy, Richa Vasan, Rosie Durant, Megan-Rose Greener, Adelynn Immanuel, Andrew R. Green, Emad Rakha, Ian Ellis, Graham Ball, Stewart G. Martin, Sarah J. Storr

Sci Rep. 2023; 13: 21163. Published online 2023 Nov 30. doi: 10.1038/s41598-023-48198-y

PMCID:: PMC10689788

Abstract Article PDF–1.7M

Select item 93880702.

DARPP32, a target of hyperactive mTORC1 in the retinal pigment epithelium

Jiyang Cai, Christopher Litwin, Rui Cheng, Jian-Xing Ma, Yan Chen

Proc Natl Acad Sci U S A. 2022 Aug 16; 119(33): e2207489119. Published online 2022 Aug 8. doi: 10.1073/pnas.2207489119

PMCID:: PMC9388070

Abstract Article PDF–1.4M

Select item 81782723.

PP1, PKA and DARPP‐32 in breast cancer: A retrospective assessment of protein and mRNA expression

Behnaz Saidy, Shreeya Kotecha, Anna Butler, Emad A. Rakha, Ian O. Ellis, Andrew R. Green, Stewart G. Martin, Sarah J. Storr

J Cell Mol Med. 2021 Jun; 25(11): 5015–5024. Published online 2021 May 15. doi: 10.1111/jcmm.16447

PMCID:: PMC8178272

Abstract Article PDF–1.0M

Select item 75417864.

Silencing of miR490–3p by H. pylori activates DARPP-32 and induces resistance to gefitinib

Shoumin Zhu, Shayan Khalafi, Zheng Chen, Julio Poveda, Dunfa Peng, Heng Lu, Mohammed Soutto, Jianwen Que, Monica Garcia-Buitrago, Alexander Zaika, Wael El-Rifai

Cancer Lett. Author manuscript; available in PMC 2021 Oct 28.

Published in final edited form as: Cancer Lett. 2020 Oct 28; 491: 87–96. Published online 2020 Jul 29. doi: 10.1016/j.canlet.2020.07.014

PMCID:: PMC7541786

Abstract Article PDF–1.8M

Select item 74630345.

ASCL1-regulated DARPP-32 and t-DARPP stimulate small cell lung cancer growth and neuroendocrine tumour cell proliferation

Sk. Kayum Alam, Li Wang, Yanan Ren, Christina E. Hernandez, Farhad Kosari, Anja C. Roden, Rendong Yang, Luke H. Hoeppner

Br J Cancer. 2020 Sep 1; 123(5): 819–832. Published online 2020 Jun 5. doi: 10.1038/s41416-020-0923-6

PMCID:: PMC7463034

Abstract Article PDF–2.3M

Select item 74176816.

Dopamine and cAMP‐regulated phosphoprotein 32kDa (DARPP‐32), protein phosphatase‐1 and cyclin‐dependent kinase 5 expression in ovarian cancer

Stewart G. Martin, Siwei Zhang, Song Yang, Behnaz Saidy, Suha Deen, Sarah J. Storr

J Cell Mol Med. 2020 Aug; 24(16): 9165–9175. Published online 2020 Jun 25. doi: 10.1111/jcmm.15553

PMCID:: PMC7417681

Abstract Article PDF–1.0M

Select item 70076907.

t-Darpp activates IGF-1R signaling to regulate glucose metabolism in trastuzumab-resistant breast cancer cells

Gal Lenz, Angelica Hamilton, Shuhui Geng, Teresa Hong, Markus Kalkum, Jamil Momand, Susan E. Kane, Janice M. Huss

Clin Cancer Res. Author manuscript; available in PMC 2020 Feb 8.

Published in final edited form as: Clin Cancer Res. 2018 Mar 1; 24(5): 1216–1226. Published online 2017 Nov 27. doi: 10.1158/1078-0432.CCR-17-0824

PMCID:: PMC7007690

Abstract Article PDF–1020K

Select item 68612718.

Dopamine and cAMP-regulated phosphoprotein 32 kDa (DARPP-32) and survival in breast cancer: a retrospective analysis of protein and mRNA expression

Shreeya Kotecha, Marie N. Lebot, Bhudsaban Sukkarn, Graham Ball, Paul M. Moseley, Stephen Y. Chan, Andrew R. Green, Emad Rakha, Ian O. Ellis, Stewart G. Martin, Sarah J. Storr

Sci Rep. 2019; 9: 16987. Published online 2019 Nov 18. doi: 10.1038/s41598-019-53529-z

PMCID:: PMC6861271

Abstract Article PDF–2.6M

Select item 67960659.

Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder

Yasuto Kunii, Mizuki Hino, Junya Matsumoto, Atsuko Nagaoka, Hiroyuki Nawa, Akiyoshi Kakita, Hiroyasu Akatsu, Yoshio Hashizume, Hirooki Yabe

Sci Rep. 2019; 9: 14877. Published online 2019 Oct 16. doi: 10.1038/s41598-019-51456-7

PMCID:: PMC6796065

Abstract Article PDF–1.2M

Select item 663915710.

Activation of IGF1R by DARPP-32 promotes STAT3 signaling in gastric cancer cells

Shoumin Zhu, Mohammed Soutto, Zheng Chen, M. Blanca Piazuelo, M. Kay Washington, Abbes Belkhiri, Alexander Zaika, Dunfa Peng, Wael El-Rifai

Oncogene. Author manuscript; available in PMC 2019 Dec 24.

Published in final edited form as: Oncogene. 2019 Jul; 38(29): 5805–5816. Published online 2019 Jun 24. doi: 10.1038/s41388-019-0843-1

Correction in:: Oncogene. 2023 Dec 11

PMCID:: PMC6639157

Abstract Article PDF–2.7M

Select item 657752611.

Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue

S Brene, N Lindefors, M Ehrlich, T Taubes, A Horiuchi, J Kopp, H Hall, G Sedvall, P Greengard, H Persson

J Neurosci. 1994 Mar 1; 14(3): 985–998. doi: 10.1523/JNEUROSCI.14-03-00985.1994

PMCID:: PMC6577526

Abstract PDF–5.6M

Select item 656474712.

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain

SI Walaas, P Greengard

J Neurosci. 1984 Jan 1; 4(1): 84–98. doi: 10.1523/JNEUROSCI.04-01-00084.1984

PMCID:: PMC6564747

Abstract PDF–2.9M

Select item 636014513.

Darpp-32 and t-Darpp protein products of PPP1R1B: old dogs with new tricks

Arabo Avanes, Gal Lenz, Jamil Momand

Biochem Pharmacol. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Biochem Pharmacol. 2019 Feb; 160: 71–79. Published online 2018 Dec 12. doi: 10.1016/j.bcp.2018.12.008

PMCID:: PMC6360145

Abstract Article PDF–793K

Select item 565118914.

t-Darpp stimulates protein kinase A activity by forming a complex with its RI regulatory subunit

Dirk Theile, Shuhui Geng, Erin C. Denny, Jamil Momand, Susan E. Kane

Cell Signal. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Cell Signal. 2017 Dec; 40: 53–61. Published online 2017 Sep 1. doi: 10.1016/j.cellsig.2017.08.012

PMCID:: PMC5651189

Abstract Article PDF–821K

Select item 564779715.

Influence of DARPP-32 genetic variation on BOLD activation to happy faces

Ninni Persson, Catarina Lavebratt, Natalie C Ebner, Håkan Fischer

Soc Cogn Affect Neurosci. 2017 Oct; 12(10): 1658–1667. Published online 2017 Jul 4. doi: 10.1093/scan/nsx089

PMCID:: PMC5647797

Abstract Article PDF–447K

Select item 556755016.

Associations Between PPP1R1B Gene Polymorphisms and Anxiety Levels in the Chinese Population

Hui Ma, Xin Li, Ailu Lin, Zhen Yuan, Jing Zhou, Xueping Yang, Zhengtu Cong, Yinglin Huang, Gang Zhu

Neurosci Bull. 2017 Feb; 33(1): 107–110. Published online 2016 Dec 19. doi: 10.1007/s12264-016-0088-8

PMCID:: PMC5567550

Article PDF–321K

Select item 553161117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 533445718.

Helicobacter pylori-induced cell death is counteracted by NF-κB-mediated transcription of DARPP-32

Shoumin Zhu, Mohammed Soutto, Zheng Chen, DunFa Peng, Judith Romero-Gallo, Uma S Krishna, Abbes Belkhiri, M Kay Washington, Richard Peek, Wael El-Rifai

Gut. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Gut. 2017 May; 66(5): 761–762. Published online 2016 Sep 2. doi: 10.1136/gutjnl-2016-312141