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Items: 1 to 20 of 57

1.
The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases
Jing Chen, Chao Ye, Chao Wan, Gang Li, Lianci Peng, Yuanyi Peng, Rendong Fang
Int J Mol Sci. 2021 Sep; 22(17): 9640. Published online 2021 Sep 6. doi: 10.3390/ijms22179640
PMCID:
PMC8431791
AbstractArticlePDF–12M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
MicroRNA-4516-mediated regulation of MAPK10 relies on 3’UTR cis-acting variants and contributes to the altered risk of Hirschsprung disease
Yang Wang, Qian Jiang, Aravinda Chakravarti, Hao Cai, Ze Xu, Wenjie Wu, Beilin Gu, Long Li, Wei Cai
J Med Genet. Author manuscript; available in PMC 2021 Feb 11.
Published in final edited form as: J Med Genet. 2020 Sep; 57(9): 634–642. Published online 2020 Feb 17. doi: 10.1136/jmedgenet-2019-106615
PMCID:
PMC7877481
AbstractArticlePDF–1.1M
4.
JNK3 as Therapeutic Target and Biomarker in Neurodegenerative and Neurodevelopmental Brain Diseases
Clara Alice Musi, Graziella Agrò, Francesco Santarella, Erika Iervasi, Tiziana Borsello
Cells. 2020 Oct; 9(10): 2190. Published online 2020 Sep 28. doi: 10.3390/cells9102190
PMCID:
PMC7600688
AbstractArticlePDF–1.8M
5.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
6.
Propofol suppresses the progression of non-small cell lung cancer via downregulation of the miR-21-5p/MAPK10 axis
Xinhua Wu, Xuebin Li, Guiping Xu
Oncol Rep. 2020 Aug; 44(2): 487–498. Published online 2020 May 21. doi: 10.3892/or.2020.7619
PMCID:
PMC7336515
AbstractArticlePDF–1.1M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Upregulation of MAPK10, TUBB2B and RASL11B may contribute to the development of neuroblastoma
Jiangtao Liu, Yulin Li
Mol Med Rep. 2019 Oct; 20(4): 3475–3486. Published online 2019 Aug 20. doi: 10.3892/mmr.2019.10589
PMCID:
PMC6755162
AbstractArticlePDF–853K
9.
Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification
Nicole A. Perry, Tamer S. Kaoud, Oscar O. Ortega, Ali I. Kaya, David J. Marcus, John M. Pleinis, Sandra Berndt, Qiuyan Chen, Xuanzhi Zhan, Kevin N. Dalby, Carlos F. Lopez, T. M. Iverson, Vsevolod V. Gurevich
Proc Natl Acad Sci U S A. 2019 Jan 15; 116(3): 810–815. Published online 2018 Dec 27. doi: 10.1073/pnas.1819230116
PMCID:
PMC6338856
AbstractArticlePDF–1.1M
10.
WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation
Woo-Jeong Jeong, Jong-Chan Park, Woo-Shin Kim, Eun Ji Ro, Soung Hoo Jeon, Sang-Kyu Lee, Young Nyun Park, Do Sik Min, Kang-Yell Choi
Nat Commun. 2019; 10: 295. Published online 2019 Jan 17. doi: 10.1038/s41467-018-08230-6
PMCID:
PMC6336889
AbstractArticlePDF–2.9M
11.
The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex
Wentao Zhang, Ning Duan, Qian Zhang, Tao Song, Zhong Li, Xun Chen, Kunzheng Wang
Int J Biol Sci. 2018; 14(14): 2023–2036. Published online 2018 Nov 3. doi: 10.7150/ijbs.28302
PMCID:
PMC6299368
AbstractArticlePDF–2.0M
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
Dysregulated miR-27a-3p promotes nasopharyngeal carcinoma cell proliferation and migration by targeting Mapk10
Lihua Li, Zhaohui Luo
Oncol Rep. 2017 May; 37(5): 2679–2687. Published online 2017 Mar 31. doi: 10.3892/or.2017.5544
PMCID:
PMC5428281
AbstractArticlePDF–869K
14.
Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease
Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman
Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387
PMCID:
PMC5260939
AbstractArticlePDF–1.1M
15.
Peptide mini-scaffold facilitates JNK3 activation in cells
Xuanzhi Zhan, Henriette Stoy, Tamer S. Kaoud, Nicole A. Perry, Qiuyan Chen, Alejandro Perez, Sylvia Els-Heindl, Jack V. Slagis, Tina M. Iverson, Annette G. Beck-Sickinger, Eugenia V. Gurevich, Kevin N. Dalby, Vsevolod V. Gurevich
Sci Rep. 2016; 6: 21025. Published online 2016 Feb 12. doi: 10.1038/srep21025
PMCID:
PMC4751492
AbstractArticlePDF–1.2M
16.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
17.
Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline
Sarah Gourmaud, Claire Paquet, Julien Dumurgier, Clarisse Pace, Constantin Bouras, Françoise Gray, Jean-Louis Laplanche, Eliane F. Meurs, François Mouton-Liger, Jacques Hugon
J Psychiatry Neurosci. 2015 May; 40(3): 151–161. Prepublished online 2014 Dec 2. doi: 10.1503/jpn.140062
PMCID:
PMC4409432
AbstractArticlePDF–1.1M
18.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
19.
Evidence of efficient stop codon readthrough in four mammalian genes
Gary Loughran, Ming-Yuan Chou, Ivaylo P. Ivanov, Irwin Jungreis, Manolis Kellis, Anmol M. Kiran, Pavel V. Baranov, John F. Atkins
Nucleic Acids Res. 2014 Aug 18; 42(14): 8928–8938. Published online 2014 Jul 10. doi: 10.1093/nar/gku608
PMCID:
PMC4132726
AbstractArticlePDF–2.3M
20.
JNK3 Is Required for the Cytoprotective Effect of Exendin 4
Hélène Ezanno, Valérie Pawlowski, Saida Abdelli, Raphael Boutry, Valery Gmyr, Julie Kerr-Conte, Christophe Bonny, François Pattou, Amar Abderrahmani
J Diabetes Res. 2014; 2014: 814854. Published online 2014 Jun 16. doi: 10.1155/2014/814854
PMCID:
PMC4083605
AbstractArticlePDF–756K

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