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Select item 111585871.

c‐Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor‐β signaling in diffuse‐type gastric carcinoma

Kunihiko Kiyono, Hiroshi I. Suzuki, Yasuyuki Morishita, Akiyoshi Komuro, Caname Iwata, Masakazu Yashiro, Kosei Hirakawa, Mitsunobu R. Kano, Kohei Miyazono

Cancer Sci. 2009 Oct; 100(10): 1809–1816. Published online 2009 Jun 17. doi: 10.1111/j.1349-7006.2009.01248.x

PMCID:: PMC11158587

Abstract Article PDF–2.0M

Select item 109332672.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 88288953.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 85645204.

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair

Maria Pilar Sanchez-Bailon, Soo-Youn Choi, Elizabeth R. Dufficy, Karan Sharma, Gavin S. McNee, Emma Gunnell, Kelly Chiang, Debashish Sahay, Sarah Maslen, Grant S. Stewart, J. Mark Skehel, Ingrid Dreveny, Clare C. Davies

Nat Commun. 2021; 12: 6313. Published online 2021 Nov 2. doi: 10.1038/s41467-021-26413-6

PMCID:: PMC8564520

Abstract Article PDF–2.3M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80866816.

Silencing of c-Ski augments TGF-β1-induced epithelial-mesenchymal transition in cardiomyocyte H9C2 cells

Jia Ling, Zhenrong Cai, Wei Jin, Xiaohua Zhuang, Lihong Kan, Fei Wang, Xiaolei Ye

Cardiol J. 2019; 26(1): 66–76. Published online 2019 Mar 14. doi: 10.5603/CJ.a2018.0009

PMCID:: PMC8086681

Abstract Article PDF–782K

Select item 80507757.

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner

Lauriane Vélot, Frédéric Lessard, Félix-Antoine Bérubé-Simard, Christophe Tav, Bertrand Neveu, Valentine Teyssier, Imène Boudaoud, Ugo Dionne, Noémie Lavoie, Steve Bilodeau, Frédéric Pouliot, Nicolas Bisson

Mol Cell Proteomics. 2021; 20: 100064. Published online 2021 Feb 26. doi: 10.1016/j.mcpro.2021.100064

PMCID:: PMC8050775

Abstract Article PDF–3.6M

Select item 78340188.

Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

Ilaria Gori, Roger George, Andrew G Purkiss, Stephanie Strohbuecker, Rebecca A Randall, Roksana Ogrodowicz, Virginie Carmignac, Laurence Faivre, Dhira Joshi, Svend Kjær, Caroline S Hill

eLife. 2021; 10: e63545. Published online 2021 Jan 8. doi: 10.7554/eLife.63545

PMCID:: PMC7834018

Abstract Article PDF–4.6M

Select item 74904489.

ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis

Haina Xie, Dongyu Xie, Jingxian Zhang, Wenye Jin, Yue Li, Jun Yao, Zhiqiang Pan, Donghao Xie

Mol Ther Nucleic Acids. 2020 Dec 4; 22: 114–123. Published online 2020 Aug 19. doi: 10.1016/j.omtn.2020.08.014

PMCID:: PMC7490448

Abstract Article PDF–2.5M

Select item 732206710.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 721376411.

SKI knockdown inhibits human melanoma tumor growth in vivo

Dahu Chen, Qiushi Lin, Neil Box, Dennis Roop, Shunsuke Ishii, Koichi Matsuzaki, Tao Fang, Thomas J. Hornyak, Jon A Reed, Ed Stavnezer, Nikolai A. Timchenko, Estela E. Medrano

Pigment Cell Melanoma Res. Author manuscript; available in PMC 2020 May 11.

Published in final edited form as: Pigment Cell Melanoma Res. 2009 Dec; 22(6): 761–772. doi: 10.1111/j.1755-148X.2009.00603.x

PMCID:: PMC7213764

Abstract Article PDF–1.9M

Select item 711512812.

Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan

Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam

Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525

PMCID:: PMC7115128

Abstract Article PDF–1.6M

Select item 694204413.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 691022414.

Knockdown of Ski decreases osteosarcoma cell proliferation and migration by suppressing the PI3K/Akt signaling pathway

Xin Zhao, Yuying Fang, Xingwen Wang, Zhouyuan Yang, Donghai Li, Meng Tian, Pengde Kang

Int J Oncol. 2020 Jan; 56(1): 206–218. Published online 2019 Nov 14. doi: 10.3892/ijo.2019.4914

PMCID:: PMC6910224

Abstract Article PDF–2.5M

Select item 655012915.

c‐Ski accelerates renal cancer progression by attenuating transforming growth factor β signaling

Luna Taguchi, Kosuke Miyakuni, Yasuyuki Morishita, Teppei Morikawa, Masashi Fukayama, Kohei Miyazono, Shogo Ehata

Cancer Sci. 2019 Jun; 110(6): 2063–2074. Published online 2019 May 3. doi: 10.1111/cas.14018

PMCID:: PMC6550129

Abstract Article PDF–927K

Select item 642009716.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

Select item 633269517.

Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes

Louise F. Porter, Neil Saptarshi, Yongxiang Fang, Sonika Rathi, Anneke I. den Hollander, Eiko K. de Jong, Simon J. Clark, Paul N. Bishop, Timothy W. Olsen, Triantafillos Liloglou, Venkata R. M. Chavali, Luminita Paraoan

Clin Epigenetics. 2019; 11: 6. Published online 2019 Jan 14. doi: 10.1186/s13148-019-0608-2

PMCID:: PMC6332695

Abstract Article PDF–1.9M

Select item 625100518.

SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness

David E. Muench, Kyle Ferchen, Chinavenmeni S. Velu, Kith Pradhan, Kashish Chetal, Xiaoting Chen, Matthew T. Weirauch, Clemencia Colmenares, Amit Verma, Nathan Salomonis, H. Leighton Grimes

Blood. 2018 Nov 22; 132(21): e24–e34. Prepublished online 2018 Sep 24. doi: 10.1182/blood-2018-06-860890

PMCID:: PMC6251005

Abstract Article

Select item 607643919.

The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation

Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin

Cancer Res. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342

PMCID:: PMC6076439

Abstract Article PDF–2.5M

Select item 603747720.

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation

Fabienne Lampert, Diana Stafa, Algera Goga, Martin Varis Soste, Samuel Gilberto, Natacha Olieric, Paola Picotti, Markus Stoffel, Matthias Peter

eLife. 2018; 7: e35528. Published online 2018 Jun 18. doi: 10.7554/eLife.35528

PMCID:: PMC6037477

Abstract Article PDF–1.5M

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