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Items: 1 to 20 of 29

1.
Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man
Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper
Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192
PMCID:
PMC9851746
AbstractArticlePDF–3.5M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
4.
TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-β-catenin signaling
Shiyuan Liu, Ying Tian, Ying Zheng, Yao Cheng, Danjie Zhang, Jiantao Jiang, Shaomin Li
Aging (Albany NY) 2020 Dec 31; 12(24): 25564–25580. Published online 2020 Dec 2. doi: 10.18632/aging.104163
PMCID:
PMC7803540
AbstractArticlePDF–3.2M
5.
The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically
Zhibin Yu, Jianbo Feng, Wei Wang, Zhiyong Deng, Yan Zhang, Lan Xiao, Zeyou Wang, Changhong Liu, Qing Liu, Shuai Chen, Minghua Wu
Oncogene. 2020; 39(15): 3163–3178. Published online 2020 Feb 13. doi: 10.1038/s41388-020-1206-7
PMCID:
PMC7142014
AbstractArticlePDF–5.4M
6.
Discovering human diabetes-risk gene function with genetics and physiological assays
Heshan Peiris, Sangbin Park, Shreya Louis, Xueying Gu, Jonathan Y. Lam, Olof Asplund, Gregory C. Ippolito, Rita Bottino, Leif Groop, Haley Tucker, Seung K. Kim
Nat Commun. 2018; 9: 3855. Published online 2018 Sep 21. doi: 10.1038/s41467-018-06249-3
PMCID:
PMC6155000
AbstractArticlePDF–2.2M
7.
The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex
Yu Zheng, Yi Zeng, Rongfang Qiu, Ruiqiong Liu, Wei Huang, Yongqiang Hou, Shuang Wang, Shuai Leng, Dandan Feng, Yang Yang, Yan Wang
Theranostics. 2018; 8(4): 972–989. Published online 2018 Jan 1. doi: 10.7150/thno.22328
PMCID:
PMC5817105
AbstractArticlePDF–3.3M
8.
SIX3 Deletions and Incomplete Penetrance in Families Affected by Holoprosencephaly
Bethany Stokes, Seth I. Berger, Beth A. Hall, Karin Weiss, Donald W. Hadley, David R. Murdock, Subhadra Ramanathan, Robin D. Clark, Erich Roessler, Paul Kruszka, Maximilian Muenke
Congenit Anom (Kyoto) Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Congenit Anom (Kyoto). 2018 Jan; 58(1): 29–32. Published online 2017 Aug 1. doi: 10.1111/cga.12234
PMCID:
PMC5750110
AbstractArticlePDF–689K
9.
SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B
Zhibin Yu, Yingnan Sun, Xiaoling She, Zeyou Wang, Shuai Chen, Zhiyong Deng, Yan Zhang, Qiang Liu, Qing Liu, Chunhua Zhao, Peiyao Li, Changhong Liu, Jianbo Feng, Haijuan Fu, Guiyuan Li, Minghua Wu
J Hematol Oncol. 2017; 10: 115. Published online 2017 Jun 8. doi: 10.1186/s13045-017-0483-2
PMCID:
PMC5465582
AbstractArticlePDF–7.7M
10.
The expression profile and clinic significance of the SIX family in non-small cell lung cancer
Qian Liu, Anping Li, Yijun Tian, Yu Liu, Tengfei Li, Cuntai Zhang, Jennifer D. Wu, Xinwei Han, Kongming Wu
J Hematol Oncol. 2016; 9: 119. Published online 2016 Nov 8. doi: 10.1186/s13045-016-0339-1
PMCID:
PMC5100270
AbstractArticlePDF–4.9M
11.
Genomic Alteration in Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Inferred from Karyotyping, Molecular Cytogenetics, and Array Comparative Genomic Hybridization
Worapong Singchat, Ekarat Hitakomate, Budsaba Rerkarmnuaychoke, Aorarat Suntronpong, Beiyuan Fu, Winai Bodhisuwan, Surin Peyachoknagul, Fengtang Yang, Sittichai Koontongkaew, Kornsorn Srikulnath
PLoS One. 2016; 11(8): e0160901. Published online 2016 Aug 8. doi: 10.1371/journal.pone.0160901
PMCID:
PMC4976893
AbstractArticlePDF–8.5M
12.
Genome-Wide Association Meta-analysis Identifies Novel Variants Associated With Fasting Plasma Glucose in East Asians
Joo-Yeon Hwang, Xueling Sim, Ying Wu, Jun Liang, Yasuharu Tabara, Cheng Hu, Kazuo Hara, Claudia H.T. Tam, Qiuyin Cai, Qi Zhao, Sunha Jee, Fumihiko Takeuchi, Min Jin Go, Rick Twee Hee Ong, Takayoshi Ohkubo, Young Jin Kim, Rong Zhang, Toshimasa Yamauchi, Wing Yee So, Jirong Long, Dongfeng Gu, Nanette R. Lee, Soriul Kim, Tomohiro Katsuya, Ji Hee Oh, Jianjun Liu, Satoshi Umemura, Yeon-Jung Kim, Feng Jiang, Shiro Maeda, Juliana C.N. Chan, Wei Lu, James E. Hixson, Linda S. Adair, Keum Ji Jung, Toru Nabika, Jae-Bum Bae, Mi Hee Lee, Mark Seielstad, Terri L. Young, Yik Ying Teo, Yoshikuni Kita, Naoyuki Takashima, Haruhiko Osawa, So-Hyun Lee, Min-Ho Shin, Dong Hoon Shin, Bo Youl Choi, Jiajun Shi, Yu-Tang Gao, Yong-Bing Xiang, Wei Zheng, Norihiro Kato, Miwuk Yoon, Jiang He, Xiao Ou Shu, Ronald C.W. Ma, Takashi Kadowaki, Weiping Jia, Tetsuro Miki, Lu Qi, E Shyong Tai, Karen L. Mohlke, Bok-Ghee Han, Yoon Shin Cho, Bong-Jo Kim
Diabetes. 2015 Jan; 64(1): 291–298. Published online 2014 Sep 3. doi: 10.2337/db14-0563
PMCID:
PMC4274808
AbstractArticlePDF–1.0M
13.
Heterozygous mutations in SIX3 and SHH are associated with schizencephaly and further expand the clinical spectrum of holoprosencephaly
Ute Hehr, Daniel E. Pineda-Alvarez, Goekhan Uyanik, Ping Hu, Nan Zhou, Andreas Hehr, Chayim Schell-Apacik, Carola Altus, Cornelia Daumer-Haas, Annechristin Meiner, Peter Steuernagel, Erich Roessler, Juergen Winkler, Maximilian Muenke
Hum Genet. Author manuscript; available in PMC 2014 Jul 17.
Published in final edited form as: Hum Genet. 2010 Mar; 127(5): 555–561. Published online 2010 Feb 16. doi: 10.1007/s00439-010-0797-4
PMCID:
PMC4101187
AbstractArticlePDF–332K
14.
Down-Regulation of SIX3 is Associated with Clinical Outcome in Lung Adenocarcinoma
Min-Li Mo, Junichi Okamoto, Zhao Chen, Tomomi Hirata, Iwao Mikami, Geneviève Bosco-Clément, Hui Li, Hai-Meng Zhou, David M. Jablons, Biao He
PLoS One. 2013; 8(8): e71816. Published online 2013 Aug 16. doi: 10.1371/journal.pone.0071816
PMCID:
PMC3745425
AbstractArticlePDF–6.2M
15.
Metastasis associated protein 1 and its short form variant stimulates Wnt1 transcription via promoting its derepression from Six3 corepressor
Rakesh Kumar, Seetharaman Balasenthil, Bramanandam Manavathi, Suresh K Rayala, Suresh B Pakala
Cancer Res. Author manuscript; available in PMC 2013 Jul 15.
Published in final edited form as: Cancer Res. 2010 Aug 15; 70(16): 6649–6658. Published online 2010 Aug 3. doi: 10.1158/0008-5472.CAN-10-0909
PMCID:
PMC3711655
AbstractArticlePDF–5.4M
16.
Clinical spectrum of SIX3-associated mutations in holoprosencephaly: correlation between genotype, phenotype and function
F Lacbawan, B D Solomon, E Roessler, K El-Jaick, S Domené, J I Vélez, N Zhou, D Hadley, J Z Balog, R Long, A Fryer, W Smith, S Omar, S D McLean, K Clarkson, A Lichty, N J Clegg, M R Delgado, E Levey, E Stashinko, L Potocki, M I VanAllen, J Clayton-Smith, D Donnai, D W Bianchi, P B Juliusson, P R Njølstad, H G Brunner, J C Carey, U Hehr, J Müsebeck, P F Wieacker, A Postra, R C M Hennekam, M-J H van den Boogaard, A van Haeringen, A Paulussen, J Herbergs, C T R M Schrander-Stumpel, A R Janecke, D Chitayat, J Hahn, D M McDonald-McGinn, E H Zackai, W B Dobyns, M Muenke
J Med Genet. Author manuscript; available in PMC 2012 Nov 30.
Published in final edited form as: J Med Genet. 2009 Jun; 46(6): 389–398. Published online 2009 Apr 2. doi: 10.1136/jmg.2008.063818
PMCID:
PMC3510661
AbstractArticlePDF–700K
17.
Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence
Lingjun Zuo, Fengyu Zhang, Heping Zhang, Xiang-Yang Zhang, Fei Wang, Chiang-Shan R. Li, Lingeng Lu, Jiang Hong, Lin Lu, John Krystal, Hong-Wen Deng, Xingguang Luo
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2012 Jun; 159B(4): 437–444. Published online 2012 Apr 4. doi: 10.1002/ajmg.b.32047
PMCID:
PMC3405545
AbstractArticlePDF–937K
18.
New findings for phenotype-genotype correlations in a large European series of holoprosencephaly cases
Sandra Mercier, Christèle Dubourg, Nicolas Garcelon, Boris Campillo-Gimenez, Isabelle Gicquel, Marion Belleguic, Leslie Ratié, Laurent Pasquier, Philippe Loget, Claude Bendavid, Sylvie Jaillard, Lucie Rochard, Chloé Quélin, Valérie Dupé, Véronique David, Sylvie Odent
J Med Genet. Author manuscript; available in PMC 2012 Nov 1.
Published in final edited form as: J Med Genet. 2011 Nov; 48(11): 752–760. Published online 2011 Sep 22. doi: 10.1136/jmedgenet-2011-100339
PMCID:
PMC3386902
AbstractArticle
19.
Utilizing prospective sequence analysis of SHH, ZIC2, SIX3 and TGIF in holoprosencephaly probands to describe the parameters limiting the observed frequency of mutant gene x gene interactions
Erich Roessler, Jorge I. Vélez, Nan Zhou, Maximilian Muenke
Mol Genet Metab. Author manuscript; available in PMC 2013 Apr 1.
Published in final edited form as: Mol Genet Metab. 2012 Apr; 105(4): 658–664. Published online 2012 Jan 12. doi: 10.1016/j.ymgme.2012.01.005
PMCID:
PMC3309119
AbstractArticlePDF–958K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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