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Items: 1 to 20 of 26

1.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
2.
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation
Gang Xu, Feiyan Deng, Qi Zuo, Lin Liu, Kaiwen Dou, Zhikui Cheng, Wei Cao, Chuanjin Luo, Chen Yu, Shi Liu, Ying Zhu
Cell Mol Immunol. 2021 Jun; 18(6): 1587–1589. Published online 2021 Mar 4. doi: 10.1038/s41423-021-00649-0
PMCID:
PMC8167138
ArticlePDF–973K
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
5.
Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms
Peter Rotwein
J Biol Chem. 2017 Jun 2; 292(22): 9252–9261. Published online 2017 Apr 7. doi: 10.1074/jbc.M117.783639
Correction in:
J Biol Chem. 2017 Dec 1; 292(48): 19608.
PMCID:
PMC5454106
AbstractArticlePDF–1016K
6.
D440N Mutation in the Acid-Labile Subunit of Insulin-Like Growth Factor Complexes Inhibits Secretion and Complex Formation
Sue M. Firth, Xiaolang Yan, Robert C. Baxter
Mol Endocrinol. February 1, 2011; 25(2): 307–314. Published online 2010 Dec 22. doi: 10.1210/me.2010-0295
PMCID:
PMC5417311
AbstractArticle
7.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
8.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
AbstractArticlePDF–630K
9.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
10.
A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3
Robert C. Kaplan, Ann-Kristin Petersen, Ming-Huei Chen, Alexander Teumer, Nicole L. Glazer, Angela Döring, Carolyn S.P. Lam, Nele Friedrich, Anne Newman, Martina Müller, Qiong Yang, Georg Homuth, Anne Cappola, Norman Klopp, Holly Smith, Florian Ernst, Bruce M. Psaty, H.-Erich Wichmann, Douglas B. Sawyer, Reiner Biffar, Jerome I. Rotter, Christian Gieger, Lisa S. Sullivan, Henry Völzke, Kenneth Rice, Ariadni Spyroglou, Heyo K. Kroemer, Y.-D. Ida Chen, Jenny Manolopoulou, Matthias Nauck, Howard D. Strickler, Mark O. Goodarzi, Martin Reincke, Michael N. Pollak, Martin Bidlingmaier, Ramachandran S. Vasan, Henri Wallaschofski
Hum Mol Genet. 2011 Mar 15; 20(6): 1241–1251. Published online 2011 Jan 7. doi: 10.1093/hmg/ddq560
PMCID:
PMC3043664
AbstractArticlePDF–423K
11.
Eighteen Insulin-like Growth Factor (IGF) pathway genes, circulating levels of IGF-1 and its binding protein (IGFBP-3), and risk of prostate and breast cancer
Fangyi Gu, Fredrick R. Schumacher, Federico Canzian, Naomi E. Allen, Demetrius Albanes, Christine D Berg, Sonja I. Berndt, Heiner Boeing, H. Bas Bueno-de-Mesquita, Julie E. Buring, Nathalie Chabbert-Buffet, Stephen J. Chanock, Françoise Clavel-Chapelon, Vanessa Dumeaux, J. Michael Gaziano, Edward L. Giovannucci, Christopher A. Haiman, Susan E. Hankinson, Richard B. Hayes, Brian E. Henderson, David J. Hunter, Robert N. Hoover, Mattias Johansson, Timothy J. Key, Kay-Tee Khaw, Laurence N. Kolonel, Pagona Lagiou, I-Min Lee, Loic LeMarchand, Eiliv Lund, Jing Ma, N. Charlotte Onland-Moret, Kim Overvad, Laudina Rodriguez, Carlotta Sacerdote, Maria-José Sánchez, Meir J. Stampfer, Pär Stattin, Daniel O. Stram, Gilles Thomas, Michael J. Thun, Anne Tjønneland, Dimitrios Trichopoulos, Rosario Tumino, Jarmo Virtamo, Stephanie J. Weinstein, Walter C. Willett, Meredith Yeager, Shumin M. Zhang, Rudolf Kaaks, Elio Riboli, Regina G. Ziegler, Peter Kraft
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11): 2877–2887. Published online 2010 Sep 1. doi: 10.1158/1055-9965.EPI-10-0507
PMCID:
PMC2989404
AbstractArticlePDF–108K
12.
A large-scale candidate-gene association study of age at menarche and age at natural menopause
Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter
Hum Genet. Author manuscript; available in PMC 2010 Nov 1.
Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4
PMCID:
PMC2967297
AbstractArticlePDF–84K
13.
Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium
Federico Canzian, David G. Cox, V. Wendy Setiawan, Daniel O. Stram, Regina G. Ziegler, Laure Dossus, Lars Beckmann, Hélène Blanché, Aurelio Barricarte, Christine D. Berg, Sheila Bingham, Julie Buring, Saundra S. Buys, Eugenia E. Calle, Stephen J. Chanock, Françoise Clavel-Chapelon, John Oliver L. DeLancey, W. Ryan Diver, Miren Dorronsoro, Christopher A. Haiman, Göran Hallmans, Susan E. Hankinson, David J. Hunter, Anika Hüsing, Claudine Isaacs, Kay-Tee Khaw, Laurence N. Kolonel, Peter Kraft, Loïc Le Marchand, Eiliv Lund, Kim Overvad, Salvatore Panico, Petra H.M. Peeters, Michael Pollak, Michael J. Thun, Anne Tjønneland, Dimitrios Trichopoulos, Rosario Tumino, Meredith Yeager, Robert N. Hoover, Elio Riboli, Gilles Thomas, Brian E. Henderson, Rudolf Kaaks, Heather Spencer Feigelson
Hum Mol Genet. 2010 Oct 1; 19(19): 3873–3884. Published online 2010 Jul 15. doi: 10.1093/hmg/ddq291
PMCID:
PMC2935856
AbstractArticlePDF–274K
14.
Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density
Margarethe Biong, Inger T Gram, Ilene Brill, Fredrik Johansen, Hiroko K Solvang, Grethe IG Alnaes, Toril Fagerheim, Yngve Bremnes, Stephen J Chanock, Laurie Burdett, Meredith Yeager, Giske Ursin, Vessela N Kristensen
BMC Med Genomics. 2010; 3: 9. Published online 2010 Mar 19. doi: 10.1186/1755-8794-3-9
PMCID:
PMC2853484
AbstractArticlePDF–326K
15.
Plasma levels of acid-labile subunit, free insulin-like growth factor-1, and prostate cancer risk: a prospective study
Lorelei A. Mucci, Jennifer R. Stark, Michael N. Pollak, Haojie Li, Tobias Kurth, Meir J. Stampfer, Jing Ma
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Feb 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2): 484. doi: 10.1158/1055-9965.EPI-09-0836
PMCID:
PMC2820127
AbstractArticlePDF–311K
16.
High-Density Association Study of 383 Candidate Genes for Volumetric BMD at the Femoral Neck and Lumbar Spine Among Older Men
Laura M. Yerges, Lambertus Klei, Jane A. Cauley, Kathryn Roeder, Candace M. Kammerer, Susan P. Moffett, Kristine E. Ensrud, Cara S. Nestlerode, Lynn M. Marshall, Andrew R. Hoffman, Cora Lewis, Thomas F. Lang, Elizabeth Barrett-Connor, Robert E. Ferrell, Eric S. Orwoll, Joseph M. Zmuda
J Bone Miner Res. 2009 Dec; 24(12): 2039–2049. Published online 2009 May 18. doi: 10.1359/JBMR.090524
PMCID:
PMC2791518
AbstractArticlePDF–759K
17.
PTEN IDENTIFIED AS IMPORTANT RISK FACTOR OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
H Dean Hosgood, III, Idan Menashe, Xingzhou He, Stephen Chanock, Qing Lan
Respir Med. Author manuscript; available in PMC 2010 Dec 1.
Published in final edited form as: Respir Med. 2009 Dec; 103(12): 1866–1870. Published online 2009 Jul 21. doi: 10.1016/j.rmed.2009.06.016
PMCID:
PMC2783799
AbstractArticlePDF–315K
18.
Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway
H.Dean Hosgood, III, Idan Menashe, Min Shen, Meredith Yeager, Jeff Yuenger, Preetha Rajaraman, Xingzhou He, Nilanjan Chatterjee, Neil E. Caporaso, Yong Zhu, Stephen J. Chanock, Tongzhang Zheng, Qing Lan
Carcinogenesis. 2008 Oct; 29(10): 1938–1943. Published online 2008 Aug 1. doi: 10.1093/carcin/bgn178
PMCID:
PMC2722857
AbstractArticlePDF–181K
19.
Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China
Min Shen, Roel Vermeulen, Preetha Rajaraman, Idan Menashe, Xingzhou He, Robert S. Chapman, Meredith Yeager, Gilles Thomas, Laurie Burdett, Amy Hutchinson, Jeff Yuenger, Stephen Chanock, Qing Lan
Environ Mol Mutagen. Author manuscript; available in PMC 2010 May 1.
Published in final edited form as: Environ Mol Mutagen. 2009 May; 50(4): 285–290. doi: 10.1002/em.20452
PMCID:
PMC2666781
AbstractArticlePDF–311K
20.
Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes
Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper
J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406
PMCID:
PMC2637050
AbstractArticle

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