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Items: 1 to 20 of 28

1.
Novel polymorphisms in CYP4A22 associated with susceptibility to coronary heart disease
Kang Huang, Tianyi Ma, Qiang Li, Zanrui Zhong, Yilei Zhou, Wei Zhang, Ting Qin, Shilin Tang, Jianghua Zhong, Shijuan Lu
BMC Med Genomics. 2024; 17: 66. Published online 2024 Mar 4. doi: 10.1186/s12920-024-01833-7
PMCID:
PMC10913669
AbstractArticlePDF–1.6M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
The role of cytochrome P450 gene rs1126742 polymorphism and risk of hypertension: a systematic review and meta-analysis
Ziyin Huang, Yufeng Jiang, Yafeng Zhou
Biosci Rep. 2020 May 29; 40(5): BSR20192513. Published online 2020 May 22. doi: 10.1042/BSR20192513
PMCID:
PMC7244898
AbstractArticlePDF–807K
4.
CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS-induced lipid peroxidation and inflammation
Huifang Gao, Yaru Cao, Hongguang Xia, Xiangyu Zhu, Yong Jin
Int J Mol Med. 2020 Apr; 45(4): 1121–1129. Published online 2020 Jan 28. doi: 10.3892/ijmm.2020.4479
PMCID:
PMC7053872
AbstractArticlePDF–755K
5.
A Novel Polymorphism in the Promoter of the CYP4A11 Gene Is Associated with Susceptibility to Coronary Artery Disease
Svetlana Sirotina, Irina Ponomarenko, Alexander Kharchenko, Marina Bykanova, Anna Bocharova, Kseniya Vagaytseva, Vadim Stepanov, Mikhail Churnosov, Maria Solodilova, Alexey Polonikov
Dis Markers. 2018; 2018: 5812802. Published online 2018 Feb 1. doi: 10.1155/2018/5812802
PMCID:
PMC5816861
AbstractArticlePDF–879K
6.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
7.
Heme–thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition
Matthew E. Albertolle, Donghak Kim, Leslie D. Nagy, Chul-Ho Yun, Ambra Pozzi, Üzen Savas, Eric F. Johnson, F. Peter Guengerich
J Biol Chem. 2017 Jul 7; 292(27): 11230–11242. Published online 2017 May 22. doi: 10.1074/jbc.M117.792200
PMCID:
PMC5500791
AbstractArticlePDF–1.2M
8.
Identification of potential candidate genes for hypertensive nephropathy based on gene expression profile
Zhi Chen, Hao Wu, Guohua Wang, Ye Feng
BMC Nephrol. 2016; 17: 149. Published online 2016 Oct 18. doi: 10.1186/s12882-016-0366-8
PMCID:
PMC5069870
AbstractArticlePDF–1.7M
9.
Interactions Among CYP2C8, EPHX2, and CYP4A11 Variants and CYP Plasma Metabolite Levels in Ischemic Stroke
Xingyang Yi, Lang Wu, Duanxiu Liao, Chun Wang, Biao Zhang
J Atheroscler Thromb. 2016 Nov 1; 23(11): 1286–1293. doi: 10.5551/jat.35279
PMCID:
PMC5065934
AbstractArticlePDF–115K
10.
20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR
Üzen Savas, Shouzou Wei, Mei-Hui Hsu, John R. Falck, F. Peter Guengerich, Jorge H. Capdevila, Eric F. Johnson
J Biol Chem. 2016 Aug 5; 291(32): 16904–16919. Published online 2016 Jun 13. doi: 10.1074/jbc.M116.732297
PMCID:
PMC4974402
AbstractArticlePDF–4.4M
11.
Interaction Between CYP4F2 rs2108622 and CPY4A11 rs9333025 Variants Is Significantly Correlated with Susceptibility to Ischemic Stroke and 20-Hydroxyeicosatetraenoic Acid Level
Duanxiu Liao, Xingyang Yi, Biao Zhang, Qiang Zhou, Jing Lin
Genet Test Mol Biomarkers. 2016 May 1; 20(5): 223–228. doi: 10.1089/gtmb.2015.0205
PMCID:
PMC4876528
AbstractArticlePDF–144K
12.
Cytochrome 4A11 Genetic Polymorphisms Increase Susceptibility to Ischemic Stroke and Associate with Atherothrombotic Events After Stroke in Chinese
Biao Zhang, Xingyang Yi, Chun Wang, Duanxiu Liao, Jing Lin, Lifen Chi
Genet Test Mol Biomarkers. 2015 May 1; 19(5): 235–241. doi: 10.1089/gtmb.2014.0305
PMCID:
PMC4432775
AbstractArticlePDF–142K
13.
Kinetic Analysis of Lauric Acid Hydroxylation by Human Cytochrome P450 4A11
Donghak Kim, Gun-Su Cha, Leslie D. Nagy, Chul-Ho Yun, F. Peter Guengerich
Biochemistry. 2014 Oct 7; 53(39): 6161–6172. Published online 2014 Sep 9. doi: 10.1021/bi500710e
PMCID:
PMC4188250
AbstractArticlePDF–1.4M
14.
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles
Jacqueline I Goldstein, L Fredrik Jarskog, Chris Hilliard, Ana Alfirevic, Laramie Duncan, Denis Fourches, Hailiang Huang, Monkol Lek, Benjamin M Neale, Stephan Ripke, Kevin Shianna, Jin P Szatkiewicz, Alexander Tropsha, Edwin JCG van den Oord, Ingolf Cascorbi, Michael Dettling, Ephraim Gazit, Donald C Goff, Arthur L Holden, Deanna L Kelly, Anil K Malhotra, Jimmi Nielsen, Munir Pirmohamed, Dan Rujescu, Thomas Werge, Deborah L Levy, Richard C Josiassen, James L Kennedy, Jeffrey A Lieberman, Mark J Daly, Patrick F Sullivan
Nat Commun. Author manuscript; available in PMC 2015 Mar 4.
Published in final edited form as: Nat Commun. 2014; 5: 4757. Published online 2014 Sep 4. doi: 10.1038/ncomms5757
PMCID:
PMC4155508
AbstractArticlePDF–1.8M
15.
GENETIC VARIATION IN CYP4A11 AND BLOOD PRESSURE RESPONSE TO MINERALOCORTICOID RECEPTOR ANTAGONISM OR ENAC INHIBITION: AN EXPLORATORY PILOT STUDY IN AFRICAN AMERICANS
Cheryl L. Laffer, Fernando Elijovich, George J. Eckert, Wanzhu Tu, J. Howard Pratt, Nancy J. Brown
J Am Soc Hypertens. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: J Am Soc Hypertens. 2014 Jul; 8(7): 475–480. Published online 2014 May 9. doi: 10.1016/j.jash.2014.04.011
PMCID:
PMC4115247
AbstractArticlePDF–421K
16.
An atlas of genetic influences on human blood metabolites
So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo
Nat Genet. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982
PMCID:
PMC4064254
AbstractArticlePDF–2.4M
17.
Association of Common Variants of CYP4A11 and CYP4F2 with Stroke in the Han Chinese Population
Hu Ding, Guanglin Cui, Lan Zhang, Yujun Xu, Xunna Bao, Yuanchao Tu, Bin Wu, Qi Wang, Rutai Hui, Wei Wang, Ryan T. Dackor, Grace E. Kissling, Darryl C. Zeldin, Dao Wen Wang
Pharmacogenet Genomics. Author manuscript; available in PMC 2014 Feb 24.
Published in final edited form as: Pharmacogenet Genomics. 2010 Mar; 20(3): 187–194. doi: 10.1097/FPC.0b013e328336eefe
PMCID:
PMC3932492
AbstractArticlePDF–102K
18.
Association between the CYP4A11 T8590C Variant and Essential Hypertension: New Data from Han Chinese and a Meta-Analysis
Hua-Cheng Yan, Jun-Hua Liu, Jian Li, Bao-Xia He, Liang Yang, Jian Qiu, Liang Li, Da-Peng Ding, Lei Shi, Shu-Jin Zhao
PLoS One. 2013; 8(11): e80072. Published online 2013 Nov 21. doi: 10.1371/journal.pone.0080072
PMCID:
PMC3836999
AbstractArticlePDF–238K
19.
Human metabolic individuality in biomedical and pharmaceutical research
Karsten Suhre, So-Youn Shin, Ann-Kristin Petersen, Robert P. Mohney, David Meredith, Brigitte Wägele, Elisabeth Altmaier, CARDIoGRAM, Panos Deloukas, Jeanette Erdmann, Elin Grundberg, Christopher J. Hammond, Martin Hrabé de Angelis, Gabi Kastenmüller, Anna Köttgen, Florian Kronenberg, Massimo Mangino, Christa Meisinger, Thomas Meitinger, Hans-Werner Mewes, Michael V. Milburn, Cornelia Prehn, Johannes Raffler, Janina S. Ried, Werner Römisch-Margl, Nilesh J. Samani, Kerrin S. Small, H.-Erich Wichmann, Guangju Zhai, Thomas Illig, Tim D. Spector, Jerzy Adamski, Nicole Soranzo, Christian Gieger
Nature. Author manuscript; available in PMC 2013 Nov 19.
Published in final edited form as: Nature. 2011 Aug 31; 477(7362): 10.1038/nature10354. Published online 2011 Aug 31. doi: 10.1038/nature10354
PMCID:
PMC3832838
AbstractArticlePDF–839K
20.
Genetic Associations with Hypertension: Meta-Analyses of Six Candidate Genetic Variants
Cheng Zhang, Lingyan Wang, Qi Liao, Lina Zhang, Leiting Xu, Cheng Chen, Huadan Ye, Xuting Xu, Meng Ye, Shiwei Duan
Genet Test Mol Biomarkers. 2013 Oct; 17(10): 736–742. doi: 10.1089/gtmb.2013.0080
PMCID:
PMC3780324
AbstractArticlePDF–400K

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