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Select item 111962931.

Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis

Fengyuan Zhang, Jiazheng Li, Jingjing Xu, Xugan Jiang, Shengxia Chen, Qais Ahmad Nasser

J Cancer Res Clin Oncol. 2024; 150(6): 323. Published online 2024 Jun 25. doi: 10.1007/s00432-024-05839-7

PMCID:: PMC11196293

Abstract Article PDF–11M

Select item 103317792.

Role and mechanism of leukemia inhibitory factor receptor in cervical cancer invasion and metastasis

Hengfen Hu, Qihui Zhao, Yufei Sang, Yanqing Xiao, Na Jiang

J Int Med Res. 2023 Jun; 51(6): 03000605231182557. Published online 2023 Jun 26. doi: 10.1177/03000605231182557

PMCID:: PMC10331779

Abstract Article PDF–570K

Select item 97934233.

The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights

Sushanta Halder, Seema Parte, Prakash Kshirsagar, Sakthivel Muniyan, Hareesh B. Nair, Surinder K. Batra, Parthasarathy Seshacharyulu

Biochim Biophys Acta Rev Cancer. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Biochim Biophys Acta Rev Cancer. 2022 Jul; 1877(4): 188737. Published online 2022 Jun 6. doi: 10.1016/j.bbcan.2022.188737

PMCID:: PMC9793423

Abstract Article PDF–2.0M

Select item 96835624.

Whole exome sequencing identifies KIF26B, LIFR and LAMC1 mutations in familial vesicoureteral reflux

Zsuzsa I. Bartik, Ulla Sillén, Anna Djos, Anna Lindholm, Susanne Fransson

PLoS One. 2022; 17(11): e0277524. Published online 2022 Nov 23. doi: 10.1371/journal.pone.0277524

PMCID:: PMC9683562

Abstract Article PDF–1.8M

Select item 92316235.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91714116.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 86834817.

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Fan Yao, Yalan Deng, Yang Zhao, Ying Mei, Yilei Zhang, Xiaoguang Liu, Consuelo Martinez, Xiaohua Su, Roberto R. Rosato, Hongqi Teng, Qinglei Hang, Shannon Yap, Dahu Chen, Yumeng Wang, Mei-Ju May Chen, Mutian Zhang, Han Liang, Dong Xie, Xin Chen, Hao Zhu, Jenny C. Chang, M. James You, Yutong Sun, Boyi Gan, Li Ma

Nat Commun. 2021; 12: 7333. Published online 2021 Dec 17. doi: 10.1038/s41467-021-27452-9

PMCID:: PMC8683481

Abstract Article PDF–7.0M

Select item 83639258.

Malignant transformation of salivary gland pleomorphic adenoma: proof of principle

Matthijs H Valstar, Hetty Mast, Ivo ten Hove, Laura R Moonen, Alfons JM Balm, Ludi E Smeele, Senada Koljenović, Winand NM Dinjens, Marie‐Louise F van Velthuysen

J Pathol Clin Res. 2021 Sep; 7(5): 432–437. Published online 2021 May 7. doi: 10.1002/cjp2.216

PMCID:: PMC8363925

Abstract Article PDF–793K

Select item 83071949.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 805439711.

CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer

Hui Zhang, Xingyuan Xiao, Wenjie Wei, Chao Huang, Miao Wang, Liang Wang, Yuanqiao He, Jiayin Sun, Yangkai Jiang, Guosong Jiang, Xiaoping Zhang

Mol Cancer. 2021; 20: 70. Published online 2021 Apr 19. doi: 10.1186/s12943-021-01360-4

PMCID:: PMC8054397

Abstract Article PDF–11M

Select item 766412012.

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane

Molly M. Hannigan, Alyson M. Hoffman, J. Will Thompson, Tianli Zheng, Christopher V. Nicchitta

Mol Cell Proteomics. 2020 Nov; 19(11): 1826–1849. Published online 2020 Aug 10. doi: 10.1074/mcp.RA120.002228

PMCID:: PMC7664120

Abstract Article PDF–4.8M

Select item 672669613.

Circular RNA circCRIM1 inhibits invasion and metastasis in lung adenocarcinoma through the microRNA (miR)‐182/miR‐93‐leukemia inhibitory factor receptor pathway

Lin Wang, Yingkuan Liang, Qixing Mao, Wenjie Xia, Bing Chen, Hongyu Shen, Lin Xu, Feng Jiang, Gaochao Dong

Cancer Sci. 2019 Sep; 110(9): 2960–2972. Published online 2019 Aug 14. doi: 10.1111/cas.14131

Correction in:: Cancer Sci. 2020 Mar; 111(3): 1031.

PMCID:: PMC6726696

Abstract Article PDF–2.8M

Select item 652502014.

TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis

Alec N. Woosley, Annamarie C. Dalton, George S. Hussey, Breege V. Howley, Bidyut K. Mohanty, Simon Grelet, Toros Dincman, Sean Bloos, Shaun K. Olsen, Philip H. Howe

Oncogene. Author manuscript; available in PMC 2019 Jul 28.

Published in final edited form as: Oncogene. 2019 May; 38(20): 3794–3811. Published online 2019 Jan 28. doi: 10.1038/s41388-019-0703-z

PMCID:: PMC6525020

Abstract Article PDF–2.9M

Select item 644186815.

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu

EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058

PMCID:: PMC6441868

Abstract Article PDF–7.0M

Select item 636721516.

A mandatory role of nuclear PAK4-LIFR axis in breast-to-bone metastasis of ERα-positive breast cancer cells

Yanshu Li, Hongyan Zhang, Yue Zhao, Chunyu Wang, Zhenguo Cheng, Lina Tang, Yunling Gao, Furong Liu, Jiabin Li, Yan Li, Yang Li, Nanxi Geng, Xue Rui, Yuee Teng, Yunpeng Liu, Liu Cao, Rakesh Kumar, Feng Jin, Feng Li

Oncogene. 2019; 38(6): 808–821. Published online 2018 Sep 3. doi: 10.1038/s41388-018-0456-0

PMCID:: PMC6367215

Abstract Article PDF–4.9M

Select item 598986717.

Long non‐coding RNA‐CTD‐2108O9.1 represses breast cancer metastasis by influencing leukemia inhibitory factor receptor

Mozhi Wang, Mengshen Wang, Zhenning Wang, Xueting Yu, Yongxi Song, Chong Wang, Yujie Xu, Fengheng Wei, Yi Zhao, Yingying Xu

Cancer Sci. 2018 Jun; 109(6): 1764–1774. Published online 2018 Apr 28. doi: 10.1111/cas.13592

PMCID:: PMC5989867

Abstract Article PDF–1.7M

Select item 582692618.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 567858119.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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