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Items: 1 to 20 of 36

1.
Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas
Ranveig S Brekke, Anny Gravdal, Khadija El Jellas, Grace E Curry, Jianguo Lin, Steven J Wilhelm, Solrun J Steine, Eric Mas, Stefan Johansson, Mark E Lowe, Bente B Johansson, Xunjun Xiao, Karianne Fjeld, Anders Molven
Hum Mol Genet. 2024 Jun 1; 33(11): 1001–1014. Published online 2024 Mar 14. doi: 10.1093/hmg/ddae034
PMCID:
PMC11102595
AbstractArticlePDF–2.3M
2.
Effects of bile salt-stimulated lipase on blood cells and associations with disease activity in human inflammatory joint disorders
Susanne Lindquist, Yuhang Wang, Eva-Lotta Andersson, Shizuko Tsuji Grebe, Gerd-Marie Alenius, Solbritt Rantapää-Dahlqvist, Lennart Lundberg, Olle Hernell
PLoS One. 2023; 18(8): e0289980. Published online 2023 Aug 11. doi: 10.1371/journal.pone.0289980
PMCID:
PMC10420350
AbstractArticlePDF–1.6M
3.
Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases
Khadija El Jellas, Petra Dušátková, Ingfrid S Haldorsen, Janne Molnes, Erling Tjora, Bente B Johansson, Karianne Fjeld, Stefan Johansson, Štěpánka Průhová, Leif Groop, J Matthias Löhr, Pål R Njølstad, Anders Molven
J Clin Endocrinol Metab. 2022 Apr; 107(4): e1455–e1466. Published online 2021 Nov 29. doi: 10.1210/clinem/dgab864
PMCID:
PMC8947231
AbstractArticle
4.
Single nucleotide polymorphisms in CEL-HYB1 increase risk for chronic pancreatitis through proteotoxic misfolding
Brett M. Cassidy, Sammy Zino, Karianne Fjeld, Anders Molven, Mark E. Lowe, Xunjun Xiao
Hum Mutat. Author manuscript; available in PMC 2020 Nov 13.
Published in final edited form as: Hum Mutat. 2020 Nov; 41(11): 1967–1978. Published online 2020 Sep 9. doi: 10.1002/humu.24105
PMCID:
PMC7663422
AbstractArticlePDF–1.3M
5.
Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells
Monica Dalva, Ida K. Lavik, Khadija El Jellas, Anny Gravdal, Aurelia Lugea, Stephen J. Pandol, Pål R. Njølstad, Richard T. Waldron, Karianne Fjeld, Bente B. Johansson, Anders Molven
Cells. 2020 Jan; 9(1): 244. Published online 2020 Jan 18. doi: 10.3390/cells9010244
PMCID:
PMC7017060
AbstractArticlePDF–15M
6.
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants
Khadija El Jellas, Bente B. Johansson, Karianne Fjeld, Aristotelis Antonopoulos, Heike Immervoll, Man H. Choi, Dag Hoem, Mark E. Lowe, Dominique Lombardo, Pål R. Njølstad, Anne Dell, Eric Mas, Stuart M. Haslam, Anders Molven
J Biol Chem. 2018 Dec 14; 293(50): 19476–19491. Published online 2018 Oct 12. doi: 10.1074/jbc.RA118.001934
PMCID:
PMC6302156
AbstractArticlePDF–5.2M
7.
Expression of truncated bile salt-dependent lipase variant in pancreatic pre-neoplastic lesions
Emmanuelle Martinez, Isabelle Crenon, Françoise Silvy, Jean Del Grande, Alice Mougel, Dolores Barea, Frederic Fina, Jean-Paul Bernard, Mehdi Ouaissi, Dominique Lombardo, Eric Mas
Oncotarget. 2017 Jan 3; 8(1): 536–551. Published online 2016 Sep 1. doi: 10.18632/oncotarget.11777
PMCID:
PMC5352176
AbstractArticlePDF–8.9M
8.
A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis
Karianne Fjeld, Frank Ulrich Weiss, Denise Lasher, Jonas Rosendahl, Jian-Min Chen, Bente B. Johansson, Holger Kirsten, Claudia Ruffert, Emmanuelle Masson, Solrun J. Steine, Peter Bugert, Miriam Cnop, Robert Grützmann, Julia Mayerle, Joachim Mössner, Monika Ringdal, Hans-Ulrich Schulz, Matthias Sendler, Peter Simon, Pawel Sztromwasser, Janniche Torsvik, Markus Scholz, Erling Tjora, Claude Férec, Heiko Witt, Markus M. Lerch, Pål R. Njølstad, Stefan Johansson, Anders Molven
Nat Genet. Author manuscript; available in PMC 2017 Feb 22.
Published in final edited form as: Nat Genet. 2015 May; 47(5): 518–522. Published online 2015 Mar 16. doi: 10.1038/ng.3249
PMCID:
PMC5321495
AbstractArticlePDF–1.4M
9.
Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis
Karianne Fjeld, Sebastian Beer, Marianne Johnstone, Constantin Zimmer, Joachim Mössner, Claudia Ruffert, Mario Krehan, Christian Zapf, Pål Rasmus Njølstad, Stefan Johansson, Peter Bugert, Fabio Miyajima, Triantafillos Liloglou, Laura J. Brown, Simon A. Winn, Kelly Davies, Diane Latawiec, Bridget K. Gunson, David N. Criddle, Munir Pirmohamed, Robert Grützmann, Patrick Michl, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
PLoS One. 2016; 11(11): e0165567. Published online 2016 Nov 1. doi: 10.1371/journal.pone.0165567
PMCID:
PMC5089759
AbstractArticlePDF–1.4M
10.
A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis
Xunjun Xiao, Gabrielle Jones, Wednesday A. Sevilla, Donna B. Stolz, Kelsey E. Magee, Margaret Haughney, Amitava Mukherjee, Yan Wang, Mark E. Lowe
J Biol Chem. 2016 Oct 28; 291(44): 23224–23236. Published online 2016 Sep 20. doi: 10.1074/jbc.M116.734384
Correction in:
J Biol Chem. 2017 May 12; 292(19): 7744.
PMCID:
PMC5087739
AbstractArticlePDF–1.2M
11.
Rs488087 single nucleotide polymorphism as predictive risk factor for pancreatic cancers
Emmanuelle Martinez, Françoise Silvy, Fréderic Fina, Marc Bartoli, Martin Krahn, Fabrice Barlesi, Dominique Figarella-Branger, Juan Iovanna, René Laugier, Mehdi Ouaissi, Dominique Lombardo, Eric Mas
Oncotarget. 2015 Nov 24; 6(37): 39855–39864. Published online 2015 Oct 16. doi: 10.18632/oncotarget.5627
PMCID:
PMC4741865
AbstractArticlePDF–2.0M
12.
Endocytosis of Secreted Carboxyl Ester Lipase in a Syndrome of Diabetes and Pancreatic Exocrine Dysfunction
Janniche Torsvik, Bente B. Johansson, Monica Dalva, Michaël Marie, Karianne Fjeld, Stefan Johansson, Geir Bjørkøy, Jaakko Saraste, Pål R. Njølstad, Anders Molven
J Biol Chem. 2014 Oct 17; 289(42): 29097–29111. Published online 2014 Aug 25. doi: 10.1074/jbc.M114.574244
PMCID:
PMC4200264
AbstractArticlePDF–5.8M
13.
Carboxyl-Ester Lipase Maturity-Onset Diabetes of the Young Is Associated With Development of Pancreatic Cysts and Upregulated MAPK Signaling in Secretin-Stimulated Duodenal Fluid
Helge Ræder, Fiona E. McAllister, Erling Tjora, Shweta Bhatt, Ingfrid Haldorsen, Jiang Hu, Stefan M. Willems, Mette Vesterhus, Abdelfattah El Ouaamari, Manway Liu, Maria B. Ræder, Heike Immervoll, Dag Hoem, Georg Dimcevski, Pål R. Njølstad, Anders Molven, Steven P. Gygi, Rohit N. Kulkarni
Diabetes. 2014 Jan; 63(1): 259–269. Published online 2013 Dec 13. doi: 10.2337/db13-1012
PMCID:
PMC3868055
AbstractArticlePDF–1.4M
14.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
AbstractArticlePDF–630K
15.
HIV-1 Disease Progression Is Associated with Bile-Salt Stimulated Lipase (BSSL) Gene Polymorphism
Martijn J. Stax, Neeltje A. Kootstra, Angélique B. van 't Wout, Michael W. T. Tanck, Margreet Bakker, Georgios Pollakis, William A. Paxton
PLoS One. 2012; 7(3): e32534. Published online 2012 Mar 6. doi: 10.1371/journal.pone.0032534
PMCID:
PMC3295759
AbstractArticlePDF–311K
16.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M
17.
BSSL and PLRP2: key enzymes for lipid digestion in the newborn examined using the Caco-2 cell line
Eva-Lotta Andersson, Olle Hernell, Lars Bläckberg, Helen Fält, Susanne Lindquist
J Lipid Res. 2011 Nov; 52(11): 1949–1956. doi: 10.1194/jlr.M015685
PMCID:
PMC3196226
AbstractArticlePDF–900K
18.
Diabetes and Pancreatic Exocrine Dysfunction Due to Mutations in the Carboxyl Ester Lipase Gene-Maturity Onset Diabetes of the Young (CEL-MODY): A PROTEIN MISFOLDING DISEASE
Bente B. Johansson, Janniche Torsvik, Lise Bjørkhaug, Mette Vesterhus, Anja Ragvin, Erling Tjora, Karianne Fjeld, Dag Hoem, Stefan Johansson, Helge Ræder, Susanne Lindquist, Olle Hernell, Miriam Cnop, Jaakko Saraste, Torgeir Flatmark, Anders Molven, Pål R. Njølstad
J Biol Chem. 2011 Oct 7; 286(40): 34593–34605. Published online 2011 Jul 22. doi: 10.1074/jbc.M111.222679
PMCID:
PMC3186416
AbstractArticlePDF–5.5M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Binding of Human Milk to Pathogen Receptor DC-SIGN Varies with Bile Salt-Stimulated Lipase (BSSL) Gene Polymorphism
Martijn J. Stax, Marloes A. Naarding, Michael W. T. Tanck, Susanne Lindquist, Olle Hernell, Robert Lyle, Per Brandtzaeg, Merete Eggesbø, Georgios Pollakis, William A. Paxton
PLoS One. 2011; 6(2): e17316. Published online 2011 Feb 28. doi: 10.1371/journal.pone.0017316
PMCID:
PMC3046167
AbstractArticlePDF–590K

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