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Select item 108692641.

Circadian modulation of glucose utilization via CRY1-mediated repression of Pdk1 expression

Yi-Ying Chiou, Cing-Yun Lee, Hao-Wei Yang, Wei-Cheng Cheng, Kun-Da Ji

J Biol Chem. 2024 Feb; 300(2): 105637. Published online 2024 Jan 8. doi: 10.1016/j.jbc.2024.105637

PMCID:: PMC10869264

Abstract Article PDF–2.7M

Select item 105437122.

Cry1Δ11 mutation induces ADHD-like symptoms through hyperactive dopamine D1 receptor signaling

Dengfeng Liu, Zhengyu Xie, Panyang Gu, Xiangyu Li, Yichun Zhang, Xinying Wang, Zhiheng Chen, Suixin Deng, Yousheng Shu, Jia-Da Li

JCI Insight. 2023 Aug 22; 8(16): e170434. Published online 2023 Aug 22. doi: 10.1172/jci.insight.170434

PMCID:: PMC10543712

Abstract Article PDF–4.8M

Select item 104244583.

The interaction between CRY1 Polymorphism and Alternative Healthy Eating Index (AHEI) on cardiovascular risk factors in overweight women and women with obesity: a cross-sectional study

Fatemeh Dehghani Firouzabadi, Atieh Mirzababaei, Farideh Shiraseb, Hadith Tangestani, Khadijeh Mirzaei

BMC Endocr Disord. 2023; 23: 172. Published online 2023 Aug 14. doi: 10.1186/s12902-023-01429-9

PMCID:: PMC10424458

Abstract Article PDF–1.1M

Select item 92152274.

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication

Hainan Liu, Yu Bai, Xun Zhang, Ting Gao, Yue Liu, Entao Li, Xuefeng Wang, Zheng Cao, Lin Zhu, Qincai Dong, Yong Hu, Guangfei Wang, Caiwei Song, Xiayang Niu, Tong Zheng, Di Wang, Zijing Liu, Yanwen Jin, Ping Li, Xiuwu Bian, Cheng Cao, Xuan Liu

J Virol. 2022 Jun; 96(12): e00412-22. Published online 2022 Jun 2. doi: 10.1128/jvi.00412-22

PMCID:: PMC9215227

Abstract Article PDF–4.2M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90163206.

A Hypoxia-Induced SCF^FBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis

Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou

Cancer Res Treat. 2022 Apr; 54(2): 525–540. Published online 2021 Jun 29. doi: 10.4143/crt.2021.373

PMCID:: PMC9016320

Abstract Article PDF–3.0M

Select item 88747097.

Circadian Gene cry Controls Tumorigenesis through Modulation of Myc Accumulation in Glioblastoma Cells

Patricia Jarabo, Carmen de Pablo, Amanda González-Blanco, Sergio Casas-Tintó

Int J Mol Sci. 2022 Feb; 23(4): 2043. Published online 2022 Feb 12. doi: 10.3390/ijms23042043

PMCID:: PMC8874709

Abstract Article PDF–2.8M

Select item 85921068.

The molecular clock gene cryptochrome 1 (CRY1) and its role in cluster headache

Carmen Fourier, Caroline Ran, Christina Sjöstrand, Elisabet Waldenlind, Anna Steinberg, Andrea Carmine Belin

Cephalalgia. 2021 Nov; 41(13): 1374–1381. Published online 2021 Jul 13. doi: 10.1177/03331024211024165

PMCID:: PMC8592106

Abstract Article PDF–596K

Select item 85698179.

CRY1 Regulates Chemoresistance in Association With NANOG by Inhibiting Apoptosis via STAT3 Pathway in Patients With Cervical Cancer

GWAN HEE HAN, JULIE KIM, HEE YUN, HANBYOUL CHO, JOON-YONG CHUNG, JAE-HOON KIM, STEPHEN M. HEWITT

Cancer Genomics Proteomics. 2021 Nov-Dec; 18(6): 699–713. Published online 2021 Nov 3. doi: 10.21873/cgp.20291

PMCID:: PMC8569817

Abstract Article PDF–9.0M

Select item 850561010.

An observational study investigating the CRY1Δ11 variant associated with delayed sleep–wake patterns and circadian metabolic output

Sandra P. Smieszek, Jennifer L. Brzezynski, Alyssa R. Kaden, Jordan A. Shinn, Jingyuan Wang, Changfu Xiao, Christos Polymeropoulos, Tayfun Özçelik, Mihael H. Polymeropoulos

Sci Rep. 2021; 11: 20103. Published online 2021 Oct 11. doi: 10.1038/s41598-021-99418-2

PMCID:: PMC8505610

Abstract Article PDF–1.1M

Select item 849374011.

Variants of the cry 1 gene may influence the effect of fat intake on resting metabolic rate in women with overweight of obesity: a cross-sectional study

Atieh Mirzababaei, Elnaz Daneshzad, Farideh Shiraseb, Sanaz Pourreza, Leila Setayesh, Cain C. T. Clark, Hadith Tangestani, Faezeh Abaj, Habib Yarizadeh, Khadijeh Mirzaei

BMC Endocr Disord. 2021; 21: 196. Published online 2021 Oct 5. doi: 10.1186/s12902-021-00860-0

PMCID:: PMC8493740

Abstract Article PDF–982K

Select item 820471112.

The Universally Conserved Residues Are Not Universally Required for Stable Protein Expression or Functions of Cryptochromes

Huachun Liu, Tiantian Su, Wenjin He, Qin Wang, Chentao Lin

Mol Biol Evol. 2020 Feb; 37(2): 327–340. Published online 2019 Sep 24. doi: 10.1093/molbev/msz217

PMCID:: PMC8204711

Abstract Article PDF–1.7M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 806709714.

Assessment of Selected Clock Proteins (CLOCK and CRY1) and Their Relationship with Biochemical, Anthropometric, and Lifestyle Parameters in Hypertensive Patients

Aniceta Ada Mikulska, Teresa Grzelak, Marta Pelczyńska, Paweł Bogdański, Krystyna Czyżewska

Biomolecules. 2021 Apr; 11(4): 517. Published online 2021 Mar 30. doi: 10.3390/biom11040517

PMCID:: PMC8067097

Abstract Article PDF–569K

Select item 786001715.

Circadian clock protein CRY1 prevents paclitaxel-induced senescence of bladder cancer cells by promoting p53 degradation

Min Jia, Bijia Su, Lijun Mo, Wen Qiu, Jiaxu Ying, Peng Lin, Bingxuan Yang, Danying Li, Dongxia Wang, Lili Xu, Hongwei Li, Zhongxin Zhou, Xing Li, Jinlong Li

Oncol Rep. 2021 Mar; 45(3): 1033–1043. Published online 2020 Dec 30. doi: 10.3892/or.2020.7914

PMCID:: PMC7860017

Abstract Article PDF–2.0M

Select item 781085216.

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

Ayesha A. Shafi, Chris M. McNair, Jennifer J. McCann, Mohammed Alshalalfa, Anton Shostak, Tesa M. Severson, Yanyun Zhu, Andre Bergman, Nicolas Gordon, Amy C. Mandigo, Saswati N. Chand, Peter Gallagher, Emanuela Dylgjeri, Talya S. Laufer, Irina A. Vasilevskaya, Matthew J. Schiewer, Michael Brunner, Felix Y. Feng, Wilbert Zwart, Karen E. Knudsen

Nat Commun. 2021; 12: 401. Published online 2021 Jan 15. doi: 10.1038/s41467-020-20513-5

PMCID:: PMC7810852

Abstract Article PDF–3.9M

Select item 766808717.

The human CRY1 tail controls circadian timing by regulating its association with CLOCK:BMAL1

Gian Carlo G. Parico, Ivette Perez, Jennifer L. Fribourgh, Britney N. Hernandez, Hsiau-Wei Lee, Carrie L. Partch

Proc Natl Acad Sci U S A. 2020 Nov 10; 117(45): 27971–27979. Published online 2020 Oct 26. doi: 10.1073/pnas.1920653117

PMCID:: PMC7668087

Abstract Article PDF–4.0M

Select item 757257218.

Cancer, hear my battle CRY

Alanna B. Chan, Katja A. Lamia

J Pineal Res. Author manuscript; available in PMC 2020 Nov 14.

Published in final edited form as: J Pineal Res. 2020 Aug; 69(1): e12658. Published online 2020 May 8. doi: 10.1111/jpi.12658

PMCID:: PMC7572572

Abstract Article PDF–629K

Select item 747680319.

Suppression of Circadian Clock Protein Cryptochrome 2 Promotes Osteoarthritis

Hirofumi Bekki, Tomas Duffy, Naoki Okubo, Merissa Olmer, Oscar Alvarez-Garcia, Katja Lamia, Steve Kay, Martin Lotz

Osteoarthritis Cartilage. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Osteoarthritis Cartilage. 2020 Jul; 28(7): 966–976. Published online 2020 Apr 24. doi: 10.1016/j.joca.2020.04.004

PMCID:: PMC7476803

Abstract Article PDF–1.7M

Select item 742732720.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

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