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Select item 110773671.

HMGA1 sensitizes esophageal squamous cell carcinoma to mTOR inhibitors through the ETS1-FKBP12 axis

Jin-Rong Guo, Kai-Yue He, Jia-Li Yuan, Wang An, Wei-Tao Yin, Qiu-Tong Li, Li-Yuan Lu, Jing-Yu Yang, Meng-Jie Liu, Yu-Jia Li, Yuan Zhao, Qi Yang, Xin-Yuan Lei, Fan Gao, Lei Zhang, Dan-Hui Wu, Jun-Qi Li, Zi-Long Zhao, Huai Liu, Ling-Jun Zhu, Xiong-Yan Xiang, Qian-Hui Sun, Yong-Ping Jian, Zhi-Xiang Xu

Int J Biol Sci. 2024; 20(7): 2640–2657. Published online 2024 Apr 22. doi: 10.7150/ijbs.95595

PMCID:: PMC11077367

Abstract Article PDF–11M

Select item 109913742.

The high FKBP1A expression in WBCs as a potential screening biomarker for pancreatic cancer

Papitchaya Watcharanurak, Apiwat Mutirangura, Vitavat Aksornkitti, Narumol Bhummaphan, Charoenchai Puttipanyalears

Sci Rep. 2024; 14: 7888. Published online 2024 Apr 3. doi: 10.1038/s41598-024-58324-z

PMCID:: PMC10991374

Abstract Article PDF–1.7M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99901784.

Therapeutic potency of compound RMY-205 for pulmonary fibrosis induced by SARS-CoV-2 nucleocapsid protein

Zhi-yuan Zhang, Cui-yu Ju, Liu-zheng Wu, Han Yan, Wen-bin Hong, Hang-zi Chen, Peng-bo Yang, Bao-Rui Wang, Tong Gou, Xiao-yan Chen, Zhi-hong Jiang, Wei-jia Wang, Tianwei Lin, Fu-nan Li, Qiao Wu

Cell Chem Biol. 2023 Mar 16; 30(3): 261–277.e8. Published online 2023 Mar 7. doi: 10.1016/j.chembiol.2023.02.004

PMCID:: PMC9990178

Abstract Article PDF–6.9M

Select item 97396875.

Upregulated FKBP1A Suppresses Glioblastoma Cell Growth via Apoptosis Pathway

Shaoyi Cai, Zhiyou Chen, Heng Tang, Siyan Meng, Liang Tao, Qin Wang

Int J Mol Sci. 2022 Dec; 23(23): 14935. Published online 2022 Nov 29. doi: 10.3390/ijms232314935

PMCID:: PMC9739687

Abstract Article PDF–2.7M

Select item 96593046.

The Prognostic Significance of FKBP1A and Its Related Immune Infiltration in Liver Hepatocellular Carcinoma

Zhongguang Li, Ying Cui, Qinchun Duan, Jianfei Zhang, Danyang Shao, Xixi Cao, Yuru Gao, Shulin Wang, Jiali Li, Odell D. Jones, Xinjuan Lei, Liyang Wang, Xin Zhou, Mengmeng Xu, Jianjie Ma, Yingli Liu, Xuehong Xu

Int J Mol Sci. 2022 Nov; 23(21): 12797. Published online 2022 Oct 24. doi: 10.3390/ijms232112797

PMCID:: PMC9659304

Abstract Article PDF–5.8M

Select item 94819337.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 92792858.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 90360929.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

Select item 879077910.

A chemical tool for blue light-inducible proximity photo-crosslinking in live cells

Pratyush Kumar Mishra, Myeong-Gyun Kang, Hakbong Lee, Seungjoon Kim, Subin Choi, Nirmali Sharma, Cheol-Min Park, Jaewon Ko, Changwook Lee, Jeong Kon Seo, Hyun-Woo Rhee

Chem Sci. 2022 Jan 26; 13(4): 955–966. Published online 2021 Dec 10. doi: 10.1039/d1sc04871f

PMCID:: PMC8790779

Abstract Article PDF–1.9M

Select item 848683211.

FKBP51 promotes invasion and migration by increasing the autophagic degradation of TIMP3 in clear cell renal cell carcinoma

Shaowei Mao, Di Zhang, Luan Chen, Jie Tan, Yunpeng Chu, Sijia Huang, Wenqi Zhou, Hengwei Qin, Qinghua Xia, Yueran Zhao, Rongxiu Li, Shengying Qin, Muyun Wei

Cell Death Dis. 2021 Oct; 12(10): 899. Published online 2021 Oct 1. doi: 10.1038/s41419-021-04192-8

PMCID:: PMC8486832

Abstract Article PDF–7.5M

Select item 836418112.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 830905013.

DCAF11 supports targeted protein degradation by electrophilic proteolysis-targeting chimeras

Xiaoyu Zhang, Lena M. Luukkonen, Christie L. Eissler, Vincent M. Crowley, Yu Yamashita, Michael A. Schafroth, Shota Kikuchi, David S. Weinstein, Kent T. Symons, Brian E. Nordin, Joe L. Rodriguez, Thomas G. Wucherpfennig, Ludwig Bauer, Melissa M. Dix, Dean Stamos, Todd M. Kinsella, Gabriel M. Simon, Kristen A. Baltgalvis, Benjamin F. Cravatt

J Am Chem Soc. Author manuscript; available in PMC 2022 Apr 7.

Published in final edited form as: J Am Chem Soc. 2021 Apr 7; 143(13): 5141–5149. Published online 2021 Mar 30. doi: 10.1021/jacs.1c00990

PMCID:: PMC8309050

Abstract Article PDF–1.4M

Select item 748475914.

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage

Marie-Christine Albert, Kerstin Brinkmann, Wojciech Pokrzywa, Saskia Diana Günther, Martin Krönke, Thorsten Hoppe, Hamid Kashkar

Cell Death Dis. 2020 Sep; 11(9): 740. Published online 2020 Sep 10. doi: 10.1038/s41419-020-02923-x

PMCID:: PMC7484759

Abstract Article PDF–2.6M

Select item 742732715.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 730600516.

Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer

Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak

Mol Cell. Author manuscript; available in PMC 2021 Jun 18.

Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027

PMCID:: PMC7306005

Abstract Article PDF–3.2M

Select item 716998317.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 714041318.

Non-Thermal Plasma Induces Antileukemic Effect Through mTOR Ubiquitination

Sun-Yong Kim, Hyo Jeong Kim, Haeng Jun Kim, Chul-Ho Kim

Cells. 2020 Mar; 9(3): 595. Published online 2020 Mar 2. doi: 10.3390/cells9030595

PMCID:: PMC7140413

Abstract Article PDF–4.3M

Select item 698120619.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 673088720.

FKBP51 and FKBP12.6—Novel and tight interactors of Glomulin

Andreas Hähle, Thomas M. Geiger, Stephanie Merz, Christian Meyners, Mao Tianqi, Jürgen Kolos, Felix Hausch

PLoS One. 2019; 14(9): e0221926. Published online 2019 Sep 6. doi: 10.1371/journal.pone.0221926

PMCID:: PMC6730887

Abstract Article PDF–1.6M

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