PMC Links for GEO Profiles (Select 132341494) - PMC

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101408004.

PFKFB4 Drives the Oncogenicity in TP53-Mutated Hepatocellular Carcinoma in a Phosphatase-Dependent Manner

Charles Shing Kam, Daniel Wai-Hung Ho, Vanessa Sheung-In Ming, Lu Tian, Karen Man-Fong Sze, Vanilla Xin Zhang, Yu-Man Tsui, Abdullah Husain, Joyce Man-Fong Lee, Carmen Chak-Lui Wong, Albert Chi-Yan Chan, Tan-To Cheung, Lo-Kong Chan, Irene Oi-Lin Ng

Cell Mol Gastroenterol Hepatol. 2023; 15(6): 1325–1350. Published online 2023 Feb 16. doi: 10.1016/j.jcmgh.2023.02.004

PMCID:: PMC10140800

Abstract Article PDF–3.4M

Select item 94826335.

PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma

Emma Phillips, Jörg Balss, Frederic Bethke, Stefan Pusch, Stefan Christen, Thomas Hielscher, Martina Schnölzer, Michael N. C. Fletcher, Antje Habel, Claudia Tessmer, Lisa-Marie Brenner, Mona Göttmann, David Capper, Christel Herold-Mende, Andreas von Deimling, Sarah-Maria Fendt, Violaine Goidts

Oncogenesis. 2022 Dec; 11(1): 57. Published online 2022 Sep 17. doi: 10.1038/s41389-022-00433-3

PMCID:: PMC9482633

Abstract Article PDF–3.4M

Select item 94778456.

Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis

Chao Lu, Pengyun Qiao, Ruihai Fu, Yadi Wang, Jiayi Lu, Xi Ling, Lu Liu, Yujun Sun, Chune Ren, Zhenhai Yu

Cell Death Dis. 2022 Sep; 13(9): 790. Published online 2022 Sep 15. doi: 10.1038/s41419-022-05241-6

Correction in:: Cell Death Dis. 2024 Jul; 15(7): 469.

PMCID:: PMC9477845

Abstract Article PDF–12M

Select item 93486647.

PFKFB4 interacts with ICMT and activates RAS/AKT signaling-dependent cell migration in melanoma

Méghane Sittewelle, Vincent Kappès, Chenxi Zhou, Déborah Lécuyer, Anne H Monsoro-Burq

Life Sci Alliance. 2022 Dec; 5(12): e202201377. Published online 2022 Aug 1. doi: 10.26508/lsa.202201377

PMCID:: PMC9348664

Abstract Article PDF–1.8M

Select item 92544798.

Hypoxia-inducible CircPFKFB4 Promotes Breast Cancer Progression by Facilitating the CRL4^DDB2 E3 Ubiquitin Ligase-mediated p27 Degradation

Hang Chen, Rui Yang, Lei Xing, Bin Wang, Dawei Liu, Xiaoqiang Ou, Yumei Deng, Rong Jiang, Junxia Chen

Int J Biol Sci. 2022; 18(9): 3888–3907. Published online 2022 Jun 6. doi: 10.7150/ijbs.72842

PMCID:: PMC9254479

Abstract Article PDF–5.0M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 904055610.

A protein interaction landscape of breast cancer

Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan

Science. Author manuscript; available in PMC 2022 Apr 26.

Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066

PMCID:: PMC9040556

Abstract Article PDF–2.2M

Select item 889702211.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 848263212.

PFKFB4 is overexpressed in clear-cell renal cell carcinoma promoting pentose phosphate pathway that mediates Sunitinib resistance

Chenchen Feng, Yuqing Li, Kunping Li, Yinfeng Lyu, Wenhui Zhu, Haowen Jiang, Hui Wen

J Exp Clin Cancer Res. 2021; 40: 308. Published online 2021 Sep 30. doi: 10.1186/s13046-021-02103-5

Correction in:: J Exp Clin Cancer Res. 2021; 40: 379.

PMCID:: PMC8482632

Abstract Article PDF–9.3M

Select item 839630413.

Expression of Alternative Splice Variants of 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase-4 in Normoxic and Hypoxic Melanoma Cells

Sonia E. Trojan, Paulina Dudzik, Justyna Totoń-Żurańska, Piotr Laidler, Kinga A. Kocemba-Pilarczyk

Int J Mol Sci. 2021 Aug; 22(16): 8848. Published online 2021 Aug 17. doi: 10.3390/ijms22168848

PMCID:: PMC8396304

Abstract Article PDF–2.4M

Select item 821151114.

PFKFB4 Overexpression Facilitates Proliferation by Promoting the G1/S Transition and Is Associated with a Poor Prognosis in Triple-Negative Breast Cancer

Yu-Chen Cai, Hang Yang, Hong-Bo Shan, Hui-Fang Su, Wen-Qi Jiang, Yan-Xia Shi

Dis Markers. 2021; 2021: 8824589. Published online 2021 Jun 9. doi: 10.1155/2021/8824589

PMCID:: PMC8211511

Abstract Article PDF–1.4M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 788781816.

PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2

Jiguang Meng, Xuxin Chen, Zhihai Han

BMC Pulm Med. 2021; 21: 60. Published online 2021 Feb 16. doi: 10.1186/s12890-021-01420-x

PMCID:: PMC7887818

Abstract Article PDF–7.2M

Select item 716998317.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 676324218.

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development

Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong

J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107

PMCID:: PMC6763242

Abstract Article PDF–12M

Select item 639403319.

Increased expression and phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoforms in urinary exosomes in pre-eclampsia

R. Ellis, M. Katerelos, S. W. Choy, N. Cook, M. Lee, K. Paizis, G. Pell, S. Walker, D. A. Power, P. F. Mount

J Transl Med. 2019; 17: 60. Published online 2019 Feb 28. doi: 10.1186/s12967-019-1806-6

PMCID:: PMC6394033

Abstract Article PDF–867K

Select item 629969020.

CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism

Ruifang Gao, Dan Li, Jing Xun, Wei Zhou, Jun Li, Juan Wang, Chen Liu, Xiru Li, Wenzhi Shen, Huan Qiao, Dwayne G. Stupack, Na Luo

Theranostics. 2018; 8(22): 6248–6262. Published online 2018 Nov 29. doi: 10.7150/thno.28721

PMCID:: PMC6299690

Abstract Article PDF–2.7M

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