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Items: 20

1.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
2.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
SFRP2/DPP4 and FMO1/LSP1 define major fibroblast populations in human skin
Tracy Tabib, Christina Morse, Ting Wang, Wei Chen, Robert Lafyatis
J Invest Dermatol. Author manuscript; available in PMC 2020 Aug 24.
Published in final edited form as: J Invest Dermatol. 2018 Apr; 138(4): 802–810. Published online 2017 Dec 6. doi: 10.1016/j.jid.2017.09.045
PMCID:
PMC7444611
AbstractArticlePDF–1.0M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
Nicotine-N’-oxidation by flavin monooxygenase enzymes
Yadira X. Perez-Paramo, Gang Chen, Joseph H. Ashmore, Christy J. W. Watson, Shamema Nasrin, Jennifer Adams-Haduch, Renwei Wang, Yu-Tang Gao, Woon-Puay Koh, Jian-Min Yuan, Philip Lazarus
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2019 Feb; 28(2): 311–320. Published online 2018 Oct 31. doi: 10.1158/1055-9965.EPI-18-0669
PMCID:
PMC6363832
AbstractArticlePDF–1.1M
7.
Targeted sequencing identifies genetic polymorphisms of flavin‐containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American
Tian‐Xiao Zhang, Nancy L. Saccone, Laura J. Bierut, John P. Rice
Brain Behav. 2017 Apr; 7(4): e00651. Published online 2017 Mar 15. doi: 10.1002/brb3.651
PMCID:
PMC5390834
AbstractArticlePDF–476K
8.
Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny
Yao Chen, Nicole R. Zane, Dhiren R. Thakker, Michael Zhuo Wang
Drug Metab Dispos. 2016 Jul; 44(7): 975–983. Published online 2016 Jul. doi: 10.1124/dmd.115.067538
PMCID:
PMC4931884
AbstractArticlePDF–1.6M
9.
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders
Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal
Cell. Author manuscript; available in PMC 2016 Apr 23.
Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013
PMCID:
PMC4441215
AbstractArticlePDF–1.2M
10.
Common polymorphisms in FMO1 are associated with nicotine dependence
Dr. Anthony L. Hinrichs, Dr. Sharon E. Murphy, Dr. Jen C. Wang, Dr. Scott Saccone, Dr. Nancy Saccone, Dr. Joe Henry Steinbach, Dr. Alison Goate, Dr. Victoria L. Stevens, Dr. Laura J. Bierut
Pharmacogenet Genomics. Author manuscript; available in PMC 2012 Jul 1.
Published in final edited form as: Pharmacogenet Genomics. 2011 Jul; 21(7): 397–402. doi: 10.1097/FPC.0b013e328346886f
PMCID:
PMC3248052
AbstractArticlePDF–307K
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease
Bradley E Aouizerat, Eric Vittinghoff, Stacy L Musone, Ludmila Pawlikowska, Pui-Yan Kwok, Jeffrey E Olgin, Zian H Tseng
BMC Cardiovasc Disord. 2011; 11: 29. Published online 2011 Jun 10. doi: 10.1186/1471-2261-11-29
PMCID:
PMC3141757
AbstractArticlePDF–275K
13.
A large-scale candidate-gene association study of age at menarche and age at natural menopause
Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter
Hum Genet. Author manuscript; available in PMC 2010 Nov 1.
Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4
PMCID:
PMC2967297
AbstractArticlePDF–84K
14.
Evaluation of Candidate Genes for Cholinesterase Activity in Farmworkers Exposed to Organophosphorus Pesticides: Association of Single Nucleotide Polymorphisms in BCHE
Timothy D. Howard, Fang-Chi Hsu, Joseph G. Grzywacz, Haiying Chen, Sara A. Quandt, Quirina M. Vallejos, Lara E. Whalley, Wei Cui, Stephanie Padilla, Thomas A. Arcury
Environ Health Perspect. 2010 Oct; 118(10): 1395–1399. Published online 2010 Jun 8. doi: 10.1289/ehp.0901764
PMCID:
PMC2957918
AbstractArticlePDF–1.5M
15.
Childhood Brain Tumors, Residential Insecticide Exposure, and Pesticide Metabolism Genes
Susan Searles Nielsen, Roberta McKean-Cowdin, Federico M. Farin, Elizabeth A. Holly, Susan Preston-Martin, Beth A. Mueller
Environ Health Perspect. 2010 Jan; 118(1): 144–149. Published online 2009 Oct 5. doi: 10.1289/ehp.0901226
PMCID:
PMC2831959
AbstractArticlePDF–336K
16.
Determination of Genetic Predisposition to Patent Ductus Arteriosus in Preterm Infants
John M Dagle, Nathan T Lepp, Margaret E Cooper, Kendra L Schaa, Keegan JP Kelsey, Kristin L Orr, Diana Caprau, Cara R Zimmerman, Katherine M Steffen, Karen J Johnson, Mary L Marazita, Jeffrey C Murray
Pediatrics. Author manuscript; available in PMC 2009 Aug 30.
Published in final edited form as: Pediatrics. 2009 Apr; 123(4): 1116–1123. doi: 10.1542/peds.2008-0313
PMCID:
PMC2734952
AbstractArticlePDF–581K
17.
Salicylic Acid–Independent ENHANCED DISEASE SUSCEPTIBILITY1 Signaling in Arabidopsis Immunity and Cell Death Is Regulated by the Monooxygenase FMO1 and the Nudix Hydrolase NUDT7
Michael Bartsch, Enrico Gobbato, Pawel Bednarek, Svenja Debey, Joachim L. Schultze, Jaqueline Bautor, Jane E. Parker
Plant Cell. 2006 Apr; 18(4): 1038–1051. doi: 10.1105/tpc.105.039982
PMCID:
PMC1425861
AbstractArticlePDF–601K
18.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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