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Select item 109500261.

Downregulation of endogenous nectin1 in human keratinocytes by herpes simplex virus 1 glycoprotein D excludes superinfection but does not affect NK cell function

Joanne Kite, Monica Hill, Natasha Preston, Anzelika Rubina, Simon Kollnberger, Eddie Chung Yern Wang, Gillian Elliott

J Gen Virol. 2024; 105(3): 001969. Published online 2024 Mar 12. doi: 10.1099/jgv.0.001969

PMCID:: PMC10950026

Abstract Article PDF–7.5M

Select item 103089522.

Ex Vivo Infection of Human Skin Models with Herpes Simplex Virus 1: Accessibility of the Receptor Nectin-1 during Formation or Impairment of Epidermal Barriers Is Restricted by Tight Junctions

Nydia C. De La Cruz, Maureen Möckel, Hanna Niehues, Matthias Rübsam, Wolfram Malter, Max Zinser, Claude Krummenacher, Dagmar Knebel-Mörsdorf

J Virol. 2023 Jun; 97(6): e00262-23. Published online 2023 Jun 8. doi: 10.1128/jvi.00262-23

PMCID:: PMC10308952

Abstract Article PDF–8.6M

Select item 97291153.

Loss of NECTIN1 triggers melanoma dissemination upon local IGF1 depletion

Julien Ablain, Amira Al Mahi, Harriet Rothschild, Meera Prasad, Sophie Aires, Song Yang, Maxim E. Dokukin, Shuyun Xu, Michelle Dang, Igor Sokolov, Christine G. Lian, Leonard I. Zon

Nat Genet. 2022; 54(12): 1839–1852. Published online 2022 Oct 13. doi: 10.1038/s41588-022-01191-z

PMCID:: PMC9729115

Abstract Article PDF–6.2M

Select item 88570494.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77002936.

Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells

Bonnie L. Hall, Daniela Leronni, Yoshitaka Miyagawa, William F. Goins, Joseph C. Glorioso, Justus B. Cohen

Int J Mol Sci. 2020 Nov; 21(22): 8815. Published online 2020 Nov 21. doi: 10.3390/ijms21228815

PMCID:: PMC7700293

Abstract Article PDF–2.6M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67379128.

Trans-endocytosis elicited by nectins transfers cytoplasmic cargo, including infectious material, between cells

Alex R. Generous, Oliver J. Harrison, Regina B. Troyanovsky, Mathieu Mateo, Chanakha K. Navaratnarajah, Ryan C. Donohue, Christian K. Pfaller, Olga Alekhina, Alina P. Sergeeva, Indrajyoti Indra, Theresa Thornburg, Irina Kochetkova, Daniel D. Billadeau, Matthew P. Taylor, Sergey M. Troyanovsky, Barry Honig, Lawrence Shapiro, Roberto Cattaneo

J Cell Sci. 2019 Aug 15; 132(16): jcs235507. Published online 2019 Aug 23. doi: 10.1242/jcs.235507

PMCID:: PMC6737912

Abstract Article

Select item 64433259.

PRR11 and SKA2 gene pair is overexpressed and regulated by p53 in breast cancer

Yitao Wang, Chunxue Zhang, Li Mai, Yulong Niu, Yingxiong Wang, Youquan Bu

BMB Rep. 2019 Feb; 52(2): 157–162. Published online 2019 Feb 28. doi: 10.5483/BMBRep.2019.52.2.207

PMCID:: PMC6443325

Abstract Article PDF–25M

Select item 638658810.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 637396711.

Interaction between nectin-1 and the human natural killer cell receptor CD96

Veronica M. Holmes, Carlos Maluquer de Motes, Paige T. Richards, Jessenia Roldan, Arjun K. Bhargava, Jordan S. Orange, Claude Krummenacher

PLoS One. 2019; 14(2): e0212443. Published online 2019 Feb 13. doi: 10.1371/journal.pone.0212443

PMCID:: PMC6373967

Abstract Article PDF–1.4M

Select item 614147012.

Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression

Gregory K. Friedman, Joshua D. Bernstock, Dongquan Chen, Li Nan, Blake P. Moore, Virginia M. Kelly, Samantha L. Youngblood, Catherine P. Langford, Xiaosi Han, Eric K. Ring, Elizabeth A. Beierle, G. Yancey Gillespie, James M. Markert

Sci Rep. 2018; 8: 13930. Published online 2018 Sep 17. doi: 10.1038/s41598-018-32353-x

PMCID:: PMC6141470

Abstract Article PDF–2.2M

Select item 612890513.

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability

Hema Adhikari, Christopher M. Counter

Nat Commun. 2018; 9: 3646. Published online 2018 Sep 7. doi: 10.1038/s41467-018-05692-6

PMCID:: PMC6128905

Abstract Article PDF–2.2M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366