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Select item 110728531.

PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem-cell-derived cardiomyocytes

Nadeera M. Wickramasinghe, David Sachs, Bhavana Shewale, David M. Gonzalez, Priyanka Dhanan-Krishnan, Denis Torre, Elizabeth LaMarca, Serena Raimo, Rafael Dariolli, Madhavika N. Serasinghe, Joshua Mayourian, Robert Sebra, Kristin Beaumont, Srinivas Iyengar, Deborah L. French, Arne Hansen, Thomas Eschenhagen, Jerry E. Chipuk, Eric A. Sobie, Adam Jacobs, Schahram Akbarian, Harry Ischiropoulos, Avi Ma’ayan, Sander M. Houten, Kevin Costa, Nicole C. Dubois

Cell Stem Cell. Author manuscript; available in PMC 2024 May 6.

Published in final edited form as: Cell Stem Cell. 2022 Apr 7; 29(4): 559–576.e7. Published online 2022 Mar 23. doi: 10.1016/j.stem.2022.02.011

PMCID:: PMC11072853

Abstract Article PDF–3.7M

Select item 109054642.

Clinical Relevance of Differential RARα and PPARβ/δ Expression in Myelodysplastic Syndromes

NIKOLAY KALITIN, GALINA DUDINA, NATALIA KOSTRITSA, ANASTASIYA SIVIRINOVA, ANDREY VAIMAN, AIDA KARAMYSHEVA

In Vivo. 2024 Mar-Apr; 38(2): 657–664. Published online 2024 Mar 3. doi: 10.21873/invivo.13486

PMCID:: PMC10905464

Abstract Article PDF–417K

Select item 107180153.

ACE I/D, ACTN3 R577X, PPARD T294C and PPARGC1AGly482Ser polymorphisms and physical fitness in Taiwanese late adolescent girls

Li-Ling Chiu, Tzu-Wen Chen, Sandy S. Hsieh, Ling-Ling Hsieh

J Physiol Sci. 2012 Mar; 62(2): 115–121. Published online 2012 Jan 14. doi: 10.1007/s12576-011-0189-0

PMCID:: PMC10718015

Abstract Article PDF–220K

Select item 96117504.

Haplotype of ESR1 and PPARD Genes Is Associated with Higher Anthropometric Changes in Han Chinese Obesity by Adjusting Dietary Factors—An 18-Month Follow-Up

Yu-Min Huang, Weu Wang, Po-Pin Hsieh, Hsin-Hung Chen

Nutrients. 2022 Oct; 14(20): 4425. Published online 2022 Oct 21. doi: 10.3390/nu14204425

PMCID:: PMC9611750

Abstract Article PDF–288K

Select item 91067165.

Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ

Yi Liu, Yasunori Deguchi, Daoyan Wei, Fuyao Liu, Micheline J. Moussalli, Eriko Deguchi, Donghui Li, Huamin Wang, Lovie Ann Valentin, Jennifer K. Colby, Jing Wang, Xiaofeng Zheng, Haoqiang Ying, Mihai Gagea, Baoan Ji, Jiaqi Shi, James C. Yao, Xiangsheng Zuo, Imad Shureiqi

Nat Commun. 2022; 13: 2665. Published online 2022 May 13. doi: 10.1038/s41467-022-30392-7

PMCID:: PMC9106716

Abstract Article PDF–6.5M

Select item 88718806.

Unraveling Gut Microbiota Signatures Associated with PPARD and PARGC1A Genetic Polymorphisms in a Healthy Population

María Bailén, Mariangela Tabone, Carlo Bressa, María Gregoria Montalvo Lominchar, Mar Larrosa, Rocío González-Soltero

Genes (Basel) 2022 Feb; 13(2): 289. Published online 2022 Feb 1. doi: 10.3390/genes13020289

PMCID:: PMC8871880

Abstract Article PDF–1.4M

Select item 88052127.

Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor δ in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative

Takuji Oyama, Kazuki Takiguchi, Hiroyuki Miyachi

Acta Crystallogr F Struct Biol Commun. 2022 Feb 1; 78(Pt 2): 81–87. Published online 2022 Jan 31. doi: 10.1107/S2053230X22000449

PMCID:: PMC8805212

Abstract Article PDF–1.2M

Select item 85887018.

PPARD rs2016520 (T/C) and NOS1AP rs12742393 (A/C) polymorphisms affect therapeutic efficacy of nateglinide in Chinese patients with type 2 diabetes mellitus

Tao Wang, Jin-Fang Song, Xue-Yan Zhou, Cheng-Lin Li, Xiao-Xing Yin, Qian Lu

BMC Med Genomics. 2021; 14: 267. Published online 2021 Nov 12. doi: 10.1186/s12920-021-01108-5

PMCID:: PMC8588701

Abstract Article PDF–793K

Select item 85639029.

N¹-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism

Yanying Wang, Jing Wang, Xiaoyu Li, Xushen Xiong, Jianyi Wang, Ziheng Zhou, Xiaoxiao Zhu, Yang Gu, Dan Dominissini, Lei He, Yong Tian, Chengqi Yi, Zusen Fan

Nat Commun. 2021; 12: 6314. Published online 2021 Nov 2. doi: 10.1038/s41467-021-26718-6

PMCID:: PMC8563902

Abstract Article PDF–5.4M

Select item 839524010.

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance

David Aguilar-Recarte, Xavier Palomer, Walter Wahli, Manuel Vázquez-Carrera

Int J Mol Sci. 2021 Aug; 22(16): 8555. Published online 2021 Aug 9. doi: 10.3390/ijms22168555

PMCID:: PMC8395240

Abstract Article PDF–1.4M

Select item 830329011.

PPARdelta in Affected Atopic Dermatitis and Psoriasis: A Possible Role in Metabolic Reprograming

Stefan Blunder, Petra Pavel, Deborah Minzaghi, Sandrine Dubrac

Int J Mol Sci. 2021 Jul; 22(14): 7354. Published online 2021 Jul 8. doi: 10.3390/ijms22147354

PMCID:: PMC8303290

Abstract Article PDF–921K

Select item 825869712.

Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ

Whitney Kilu, Daniel Merk, Dieter Steinhilber, Ewgenij Proschak, Jan Heering

J Biol Chem. 2021 Jul; 297(1): 100814. Published online 2021 May 31. doi: 10.1016/j.jbc.2021.100814

PMCID:: PMC8258697

Abstract Article PDF–2.8M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 811324414.

Associations among perfluorooctanesulfonic/perfluorooctanoic acid levels, nuclear receptor gene polymorphisms, and lipid levels in pregnant women in the Hokkaido study

Sumitaka Kobayashi, Fumihiro Sata, Houman Goudarzi, Atsuko Araki, Chihiro Miyashita, Seiko Sasaki, Emiko Okada, Yusuke Iwasaki, Tamie Nakajima, Reiko Kishi

Sci Rep. 2021; 11: 9994. Published online 2021 May 11. doi: 10.1038/s41598-021-89285-2

PMCID:: PMC8113244

Abstract Article PDF–2.5M

Select item 800904815.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239