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Select item 109581811.

Non‐targeted metabolomics for the identification of plasma metabolites associated with organic anion transporting polypeptide 1B1 function

Kreetta Hämäläinen, Päivi Hirvensalo, Mikko Neuvonen, Aleksi Tornio, Janne T. Backman, Marko Lehtonen, Mikko Niemi

Clin Transl Sci. 2024 Mar; 17(3): e13773. Published online 2024 Mar 22. doi: 10.1111/cts.13773

PMCID:: PMC10958181

Abstract Article PDF–1010K

Select item 108853472.

The impact of SLCO1B1 rs4149056 on LDL-C target achievement after lipid lowering therapy optimization in men and women with familial hypercholesterolemia

Giosiana Bosco, Francesco Di Giacomo Barbagallo, Maurizio Di Marco, Nicoletta Miano, Sabrina Scilletta, Salvatore Spampinato, Alessio Vitale, Federica Di Bella, Maria Montalbano, Stefania Di Mauro, Agnese Filippello, Alessandra Scamporrino, Agostino Milluzzo, Antonino Di Pino, Lucia Frittitta, Francesco Purrello, Salvatore Piro, Roberto Scicali

Front Endocrinol (Lausanne) 2024; 15: 1346152. Published online 2024 Feb 8. doi: 10.3389/fendo.2024.1346152

PMCID:: PMC10885347

Abstract Article PDF–640K

Select item 108118933.

Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population

Juan Fan, Hua-Yun He, Huan-Huan Li, Pi-Liu Wu, Lei Tang, Bo-Yin Deng, Wen-Hui Dong, Jian-Hui Wang

BMC Pediatr. 2024; 24: 82. Published online 2024 Jan 26. doi: 10.1186/s12887-024-04537-0

PMCID:: PMC10811893

Abstract Article PDF–1.2M

Select item 107094094.

Cryo-EM structures of human organic anion transporting polypeptide OATP1B1

Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang

Cell Res. 2023 Dec; 33(12): 940–951. Published online 2023 Sep 6. doi: 10.1038/s41422-023-00870-8

PMCID:: PMC10709409

Abstract Article PDF–6.3M

Select item 105200585.

Association between SLCO1B1 genetic polymorphisms and bleeding risk in patients treated with edoxaban

Ji Min Han, Eun Jeong Jang, Jeong Yee, Tae-Jin Song, Dong-Hyeok Kim, Junbeom Park, Hye Sun Gwak

Sci Rep. 2023; 13: 15967. Published online 2023 Sep 25. doi: 10.1038/s41598-023-43179-7

PMCID:: PMC10520058

Abstract Article PDF–1.0M

Select item 105070186.

Structure of human drug transporters OATP1B1 and OATP1B3

Anca-Denise Ciută, Kamil Nosol, Julia Kowal, Somnath Mukherjee, Ana S. Ramírez, Bruno Stieger, Anthony A. Kossiakoff, Kaspar P. Locher

Nat Commun. 2023; 14: 5774. Published online 2023 Sep 18. doi: 10.1038/s41467-023-41552-8

PMCID:: PMC10507018

Abstract Article PDF–4.4M

Select item 105069067.

SLCO1B1*5 is protective against non-senile cataracts in cohort prescribed statins: analysis in a British-South Asian cohort

Emma F. Magavern, David A. van Heel, Genes & Health Research Team, Damian Smedley, Mark J. Caulfield

Pharmacogenomics J. 2023; 23(5): 134–139. Published online 2023 May 23. doi: 10.1038/s41397-023-00307-w

PMCID:: PMC10506906

Abstract Article PDF–834K

Select item 102424348.

The frequency of major ABCG2, SLCO1B1 and CYP2C9 variants in Asian, Native Hawaiian and Pacific Islander women subgroups: implications for personalized statins dosing

Khalifa Alrajeh, Ola AlAzzeh, Youssef Roman

Pharmacogenomics. 2023 May; 24(7): 381–398. Published online 2023 May 24. doi: 10.2217/pgs-2023-0043

PMCID:: PMC10242434

Abstract Article PDF–628K

Select item 99968219.

Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder

Katja Häkkinen, Wilma Kiander, Heidi Kidron, Markku Lähteenvuo, Lea Urpa, Jonne Lintunen, Kati-Sisko Vellonen, Seppo Auriola, Minna Holm, Kaisla Lahdensuo, Olli Kampman, Erkki Isometsä, Tuula Kieseppä, Jouko Lönnqvist, Jaana Suvisaari, Jarmo Hietala, Jari Tiihonen, Aarno Palotie, Ari V. Ahola-Olli, Mikko Niemi

Mol Pharm. 2023 Mar 6; 20(3): 1500–1508. Published online 2023 Feb 13. doi: 10.1021/acs.molpharmaceut.2c00715

PMCID:: PMC9996821

Abstract Article PDF–3.3M

Select item 988941710.

Effects of the SLCO1B1 A388G single nucleotide polymorphism on the development, clinical parameters, treatment, and survival of multiple myeloma cases in a Polish population

Katarzyna Michalska, Ewa Balcerczak, Agnieszka Jeleń, Lias Saed, Jacek Pietrzak, Marta Żebrowska-Nawrocka

Mol Biol Rep. 2023; 50(2): 1447–1458. Published online 2022 Dec 7. doi: 10.1007/s11033-022-08162-x

PMCID:: PMC9889417

Abstract Article PDF–956K

Select item 962956711.

Association between single nucleotide polymorphism SLCO1B1 gene and simvastatin pleiotropic effects measured through flow-mediated dilation endothelial function parameters

Andrianto, Mia Puspitasari, Meity Ardiana, Ivana Purnama Dewi, Khubay Alvia Shonafi, Louisa Fadjri Kusuma Wardhani, Ricardo Adrian Nugraha

Ther Adv Cardiovasc Dis. 2022; 16: 17539447221132367. Published online 2022 Oct 31. doi: 10.1177/17539447221132367

PMCID:: PMC9629567

Abstract Article PDF–509K

Select item 930359212.

SLCO1B1*5 Allele Is Associated With Atorvastatin Discontinuation and Adverse Muscle Symptoms in the Context of Routine Care

Deepak Voora, Jordan Baye, Adam McDermaid, Smitha Narayana Gowda, Russell A. Wilke, Anna Nicole Myrmoe, Catherine Hajek, Eric A. Larson

Clin Pharmacol Ther. 2022 May; 111(5): 1075–1083. Published online 2022 Feb 5. doi: 10.1002/cpt.2527

PMCID:: PMC9303592

Abstract Article PDF–380K

Select item 929257213.

Performance of Plasma Coproporphyrin I and III as OATP1B1 Biomarkers in Humans

Mikko Neuvonen, Aleksi Tornio, Päivi Hirvensalo, Janne T. Backman, Mikko Niemi

Clin Pharmacol Ther. 2021 Dec; 110(6): 1622–1632. Published online 2021 Oct 15. doi: 10.1002/cpt.2429

PMCID:: PMC9292572

Abstract Article PDF–708K

Select item 919023314.

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier

Raymond K. Hau, Robert R. Klein, Stephen H. Wright, Nathan J. Cherrington

Drug Metab Dispos. 2022 Jun; 50(6): 770–780. Published online 2022 Jun. doi: 10.1124/dmd.121.000748

PMCID:: PMC9190233

Abstract Article PDF–2.8M

Select item 905938915.

Associations between UGT1A1 and SLCO1B1 polymorphisms and susceptibility to neonatal hyperbilirubinemia in Thai population

Chalirmporn Atasilp, Janjira Kanjanapipak, Jaratdao Vichayaprasertkul, Pimonpan Jinda, Rawiporn Tiyasirichokchai, Pornpen Srisawasdi, Chatchay Prempunpong, Monpat Chamnanphon, Apichaya Puangpetch, Natchaya Vanwong, Suwit Klongthalay, Thawinee Jantararoungtong, Chonlaphat Sukasem

BMC Pediatr. 2022; 22: 243. Published online 2022 May 2. doi: 10.1186/s12887-022-03311-4

PMCID:: PMC9059389

Abstract Article PDF–877K

Select item 874263916.

SLCO1B1 *15 allele is associated with methotrexate‐induced nausea in pediatric patients with inflammatory bowel disease

Rishi S. Mehta, Zachary L. Taylor, Lisa J. Martin, Michael J. Rosen, Laura B. Ramsey

Clin Transl Sci. 2022 Jan; 15(1): 63–69. Published online 2021 Aug 23. doi: 10.1111/cts.13130

PMCID:: PMC8742639

Abstract Article PDF–343K

Select item 860222917.

The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality

Wilma Kiander, Kati-Sisko Vellonen, Melina M. Malinen, Mikko Gynther, Marja Hagström, Madhushree Bhattacharya, Seppo Auriola, Jan B. Koenderink, Heidi Kidron

Pharm Res. 2021; 38(10): 1663–1675. Published online 2021 Oct 13. doi: 10.1007/s11095-021-03107-8