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Select item 110695231.

Study of the potential role of CASPASE-10 mutations in the development of autoimmune lymphoproliferative syndrome

Filippo Consonni, Solange Moreno, Blanca Vinuales Colell, Marie-Claude Stolzenberg, Alicia Fernandes, Mélanie Parisot, Cécile Masson, Nathalie Neveux, Jérémie Rosain, Sarah Bamberger, Marie-Gabrielle Vigue, Marion Malphettes, Pierre Quartier, Capucine Picard, Frédéric Rieux-Laucat, Aude Magerus

Cell Death Dis. 2024 May; 15(5): 315. Published online 2024 May 4. doi: 10.1038/s41419-024-06679-6

PMCID:: PMC11069523

Abstract Article PDF–1.1M

Select item 93383132.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 91775993.

ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB

Minho Won, Kyeong Ah Park, Sup Kim, Eunjin Ju, Youngbok Ko, Heonjong Yoo, Hyunju Ro, Jaeseob Lee, Junseo Oh, Eun Gyo Lee, Sang Yean Kim, Suk Woo Nam, Han-Ming Shen, Min-Kyung Yeo, Jin Man Kim, Gang Min Hur

Cell Death Differ. 2022 Jun; 29(6): 1152–1163. Published online 2021 Nov 27. doi: 10.1038/s41418-021-00906-9

PMCID:: PMC9177599

Abstract Article PDF–3.4M

Select item 91714114.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 82827645.

N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017

PMCID:: PMC8282764

Abstract Article PDF–3.4M

Select item 67511596.

Caspase-10 inhibits ATP-citrate lyase-mediated metabolic and epigenetic reprogramming to suppress tumorigenesis

Rajni Kumari, Ruhi S. Deshmukh, Sanjeev Das

Nat Commun. 2019; 10: 4255. Published online 2019 Sep 18. doi: 10.1038/s41467-019-12194-6

PMCID:: PMC6751159

Abstract Article PDF–2.4M

Select item 64418687.

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu

EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058

PMCID:: PMC6441868

Abstract Article PDF–7.0M

Select item 57051538.

Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10

Olga Vondálová Blanářová, Barbora Šafaříková, Jarmila Herůdková, Martin Krkoška, Silvie Tománková, Zuzana Kahounová, Ladislav Anděra, Jan Bouchal, Gvantsa Kharaishvili, Milan Král, Petr Sova, Alois Kozubík, Alena Hyršlová Vaculová

PLoS One. 2017; 12(11): e0188584. Published online 2017 Nov 28. doi: 10.1371/journal.pone.0188584

PMCID:: PMC5705153

Abstract Article PDF–4.4M

Select item 54135859.

Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival

Sebastian Horn, Michelle A. Hughes, Ramon Schilling, Carsten Sticht, Tencho Tenev, Michaela Ploesser, Pascal Meier, Martin R. Sprick, Marion MacFarlane, Martin Leverkus

Cell Rep. 2017 Apr 25; 19(4): 785–797. Published online 2017 Apr 25. doi: 10.1016/j.celrep.2017.04.010

PMCID:: PMC5413585

Abstract Article

Select item 521485710.

SUMO-Modified FADD Recruits Cytosolic Drp1 and Caspase-10 to Mitochondria for Regulated Necrosis

Seon-Guk Choi, Hyunjoo Kim, Eun Il Jeong, Ho-June Lee, Sungwoo Park, Song-Yi Lee, Hyeon-Jeong Lee, Seong Won Lee, Chin Ha Chung, Yong-Keun Jung

Mol Cell Biol. 2017 Jan 15; 37(2): e00254-16. Prepublished online 2016 Oct 31. Published online 2017 Jan 4. doi: 10.1128/MCB.00254-16

PMCID:: PMC5214857

Abstract Article PDF–4.5M

Select item 488219011.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 444121512.

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal

Cell. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013

PMCID:: PMC4441215

Abstract Article PDF–1.2M

Select item 426658813.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 422689214.

Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic lupus erythematosus

Yu-Jih Su, Tien-Tsai Cheng, Chung-Jen Chen, Wen-Neng Chang, Nai-Wen Tsai, Chia-Te Kung, Hung-Chen Wang, Wei-Che Lin, Chih-Cheng Huang, Ya-Ting Chang, Chih-Min Su, Yi-Fang Chiang, Ben-Chung Cheng, Yu-Jun Lin, Cheng-Hsien Lu

J Transl Med. 2014; 12: 303. Published online 2014 Nov 6. doi: 10.1186/s12967-014-0303-1

PMCID:: PMC4226892

Abstract Article PDF–1014K

Select item 419973915.

Transcriptomic Analysis Unveils Correlations between Regulative Apoptotic Caspases and Genes of Cholesterol Homeostasis in Human Brain

Raffaella Picco, Andrea Tomasella, Federico Fogolari, Claudio Brancolini

PLoS One. 2014; 9(10): e110610. Published online 2014 Oct 16. doi: 10.1371/journal.pone.0110610

PMCID:: PMC4199739

Abstract Article PDF–2.8M

Select item 405983216.

Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma

Laurence Lamy, Vu N. Ngo, Tolga N. C. Emre, Arthur L. Shaffer, III, Yandan Yang, Erming Tian, Vinod Nair, Michael J. Kruhlak, Adriana Zingone, Ola Landgren, Louis M. Staudt

Cancer Cell. Author manuscript; available in PMC 2014 Jun 17.

Published in final edited form as: Cancer Cell. 2013 Apr 15; 23(4): 435–449. Published online 2013 Mar 28. doi: 10.1016/j.ccr.2013.02.017

PMCID:: PMC4059832

Abstract Article PDF–1.9M

Select item 397962217.

Association of polymorphisms in CASP10 and CASP8 with FEV₁/FVC and bronchial hyperresponsiveness in ethnically diverse asthmatics

Alicia K. Smith, Leslie A. Lange, Elizabeth J. Ampleford, Deborah A. Meyers, Eugene R. Bleecker, Timothy D. Howard

Clin Exp Allergy. Author manuscript; available in PMC 2014 Apr 8.

Published in final edited form as: Clin Exp Allergy. 2008 Nov; 38(11): 1738–1744. Published online 2008 Sep 24. doi: 10.1111/j.1365-2222.2008.03095.x

PMCID:: PMC3979622

Abstract Article PDF–264K

Select item 385848718.

Genetic variants in Fas signaling pathway genes and risk of gastric cancer

Paula L. Hyland, Shih-Wen Lin, Nan Hu, Han Zhang, Lemin Wang, Hua Su, Chaoyu Wang, Ti Ding, Ze-Zhong Tang, Jin-Hu Fan, You-Lin Qiao, Xiaoqin Xiong, William Wheeler, Carol Giffen, Kai Yu, Jeff Yuenger, Laurie Burdett, Zhaoming Wang, Stephen J. Chanock, Margaret A. Tucker, Sanford M. Dawsey, Neal D. Freedman, Alisa M. Goldstein, Christian C. Abnet, Philip R Taylor

Int J Cancer. Author manuscript; available in PMC 2015 Feb 15.

Published in final edited form as: Int J Cancer. 2014 Feb 15; 134(4): 822–831. Published online 2013 Sep 11. doi: 10.1002/ijc.28415

PMCID:: PMC3858487

Abstract Article PDF–423K

Select item 372992719.

Genome-wide Association Study Identifies Multiple Risk Loci for Chronic Lymphocytic Leukemia

Sonja I. Berndt, Christine F. Skibola, Vijai Joseph, Nicola J. Camp, Alexandra Nieters, Zhaoming Wang, Wendy Cozen, Alain Monnereau, Sophia S. Wang, Rachel S. Kelly, Qing Lan, Lauren R. Teras, Nilanjan Chatterjee, Charles C. Chung, Meredith Yeager, Angela R. Brooks-Wilson, Patricia Hartge, Mark P. Purdue, Brenda M. Birmann, Bruce K. Armstrong, Pierluigi Cocco, Yawei Zhang, Gianluca Severi, Anne Zeleniuch-Jacquotte, Charles Lawrence, Laurie Burdette, Jeffrey Yuenger, Amy Hutchinson, Kevin B. Jacobs, Timothy G. Call, Tait D. Shanafelt, Anne J. Novak, Neil E. Kay, Mark Liebow, Alice H. Wang, Karin E Smedby, Hans-Olov Adami, Mads Melbye, Bengt Glimelius, Ellen T. Chang, Martha Glenn, Karen Curtin, Lisa A. Cannon-Albright, Brandt Jones, W. Ryan Diver, Brian K. Link, George J. Weiner, Lucia Conde, Paige M. Bracci, Jacques Riby, Elizabeth A. Holly, Martyn T. Smith, Rebecca D. Jackson, Lesley F. Tinker, Yolanda Benavente, Nikolaus Becker, Paolo Boffetta, Paul Brennan, Lenka Foretova, Marc Maynadie, James McKay, Anthony Staines, Kari G. Rabe, Sara J. Achenbach, Celine M. Vachon, Lynn R Goldin, Sara S. Strom, Mark C. Lanasa, Logan G. Spector, Jose F. Leis, Julie M. Cunningham, J. Brice Weinberg, Vicki A. Morrison, Neil E. Caporaso, Aaron D. Norman, Martha S. Linet, Anneclaire J. De Roos, Lindsay M. Morton, Richard K. Severson, Elio Riboli, Paolo Vineis, Rudolph Kaaks, Dimitrios Trichopoulos, Giovanna Masala, Elisabete Weiderpass, María-Dolores Chirlaque, Roel C H Vermeulen, Ruth C. Travis, Graham G. Giles, Demetrius Albanes, Jarmo Virtamo, Stephanie Weinstein, Jacqueline Clavel, Tongzhang Zheng, Theodore R Holford, Kenneth Offit, Andrew Zelenetz, Robert J. Klein, John J. Spinelli, Kimberly A. Bertrand, Francine Laden, Edward Giovannucci, Peter Kraft, Anne Kricker, Jenny Turner, Claire M. Vajdic, Maria Grazia Ennas, Giovanni M. Ferri, Lucia Miligi, Liming Liang, Joshua Sampson, Simon Crouch, Ju-hyun Park, Kari E. North, Angela Cox, John A. Snowden, Josh Wright, Angel Carracedo, Carlos Lopez-Otin, Silvia Bea, Itziar Salaverria, David Martin, Elias Campo, Joseph F. Fraumeni, Jr, Silvia de Sanjose, Henrik Hjalgrim, James R. Cerhan, Stephen J. Chanock, Nathaniel Rothman, Susan L. Slager

Nat Genet. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 868–876. Published online 2013 Jun 16. doi: 10.1038/ng.2652