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Select item 111599601.

Requirement of phosphatase of regenerating liver‐3 for the nucleolar localization of nucleolin during the progression of colorectal carcinoma

Shuho Semba, Eri Mizuuchi, Hiroshi Yokozaki

Cancer Sci. 2010 Oct; 101(10): 2254–2261. Published online 2010 Jun 19. doi: 10.1111/j.1349-7006.2010.01651.x

PMCID:: PMC11159960

Abstract Article PDF–912K

Select item 90163202.

A Hypoxia-Induced SCF^FBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis

Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou

Cancer Res Treat. 2022 Apr; 54(2): 525–540. Published online 2021 Jun 29. doi: 10.4143/crt.2021.373

PMCID:: PMC9016320

Abstract Article PDF–3.0M

Select item 89739393.

The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with β3 –tubulin

Zhenying Ge, Tingxuan Gu, Lingge Zhang, Qingfang Fan, Li Ma, Na Fang

Bioengineered. 2022; 13(2): 4112–4121. Published online 2022 Feb 12. doi: 10.1080/21655979.2021.2001220

PMCID:: PMC8973939

Abstract Article PDF–853K

Select item 84950084.

PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma

Qian Song, Yutian Zheng, Junzhou Wu, Sheng Wang, Lin Meng, Qian Yao, Zhongwu Li, Shenyi Lian

Front Immunol. 2021; 12: 717688. Published online 2021 Sep 23. doi: 10.3389/fimmu.2021.717688

PMCID:: PMC8495008

Abstract Article PDF–5.6M

Select item 84554045.

The phosphatase PRL-3 affects intestinal homeostasis by altering the crypt cell composition

Teresa Rubio, Judith Weyershaeuser, Marta G. Montero, Andreas Hoffmann, Pablo Lujan, Martin Jechlinger, Rocio Sotillo, Maja Köhn

J Mol Med (Berl) 2021; 99(10): 1413–1426. Published online 2021 Jun 15. doi: 10.1007/s00109-021-02097-9

PMCID:: PMC8455404

Abstract Article PDF–4.9M

Select item 83299226.

Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer

John S. Lazo, Elizabeth R. Sharlow, Robert Cornelison, Duncan J. Hart, Danielle C. Llaneza, Anna J. Mendelson, Ettore J. Rastelli, Nikhil R. Tasker, Charles N. Landen, Jr., Peter Wipf

Biomolecules. 2021 Jul; 11(7): 969. Published online 2021 Jun 30. doi: 10.3390/biom11070969

PMCID:: PMC8329922

Abstract Article PDF–1.9M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80090538.

PRL3 enhances T cell acute lymphoblastic leukemia growth through suppressing T cell signaling pathways and apoptosis

E.G. Garcia, A. Veloso, M.L. Oliveira, J. R. Allen, S. Loontiens, D. Brunson, D. Do, C. Yan, R. Morris, S. Iyer, S.P. Garcia, N. Iftimia, Loocke W. a, F. Matthijssens, K. McCarthy, J.T. Barata, F. Speleman, T. Taghon, A. Gutierrez, P. Van Vlierberghe, W. Haas, J.S. Blackburn, D.M. Langenau

Leukemia. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Leukemia. 2021 Mar; 35(3): 679–690. Published online 2020 Jun 30. doi: 10.1038/s41375-020-0937-3

PMCID:: PMC8009053

Abstract Article PDF–1.4M

Select item 77699849.

Correlation of PRL3 expression with colorectal cancer progression

Premila D. Leiphrakpam, Audrey J. Lazenby, Lynette M. Smith, Michael G. Brattain, Jennifer D. Black, Jing Wang, Chandrakanth Are

J Surg Oncol. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: J Surg Oncol. 2021 Jan; 123(1): 42–51. Published online 2020 Nov 12. doi: 10.1002/jso.26253

PMCID:: PMC7769984

Abstract Article PDF–2.2M

Select item 748141410.

PRL-3 facilitates Hepatocellular Carcinoma progression by co-amplifying with and activating FAK

Qiming Zhou, Qianlei Zhou, Qinghua Liu, Zhanghai He, Yongcong Yan, Jianhong Lin, Zheng Chen, Chuanchao He, Kai Mao, Jie Wang, Zhenyu Zhou, Zhiyu Xiao, Jianlong Zhang

Theranostics. 2020; 10(22): 10345–10359. Published online 2020 Aug 18. doi: 10.7150/thno.42069

PMCID:: PMC7481414

Abstract Article PDF–3.3M

Select item 745012111.

PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth

Guennadi Kozlov, Yosuke Funato, Yu Seby Chen, Zhidian Zhang, Katalin Illes, Hiroaki Miki, Kalle Gehring

J Biol Chem. 2020 Aug 14; 295(33): 11682–11692. Published online 2020 Jun 22. doi: 10.1074/jbc.RA120.014464

PMCID:: PMC7450121

Abstract Article PDF–2.2M

Select item 743569912.

PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation

Jeanette A. Johansson, Kerrie L. Marie, Yuting Lu, Alessandro Brombin, Cristina Santoriello, Zhiqiang Zeng, Judith Zich, Philippe Gautier, Alex von Kriegsheim, Hannah Brunsdon, Ann P. Wheeler, Marcel Dreger, Douglas R. Houston, Christopher M. Dooley, Andrew H. Sims, Elisabeth M. Busch-Nentwich, Leonard I. Zon, Robert S. Illingworth, E. Elizabeth Patton

Dev Cell. 2020 Aug 10; 54(3): 317–332.e9. doi: 10.1016/j.devcel.2020.06.013

PMCID:: PMC7435699

Abstract Article

Select item 678197613.

PRL-3 exerts oncogenic functions in myeloid leukemia cells via aberrant dephosphorylation of stathmin and activation of STAT3 signaling

Jianping Xu, Wei Wu, Yao Tang, Yanfeng Lin, Yan Xue, Jianda Hu, Donghong Lin

Aging (Albany NY) 2019 Sep 30; 11(18): 7817–7829. Published online 2019 Sep 23. doi: 10.18632/aging.102290

PMCID:: PMC6781976

Abstract Article PDF–5.4M

Select item 655429514.

PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein

Min Thura, Abdul Qader Al-Aidaroos, Abhishek Gupta, Cheng Ean Chee, Soo Chin Lee, Kam Man Hui, Jie Li, Yeoh Khay Guan, Wei Peng Yong, Jimmy So, Wee Joo Chng, Chin Hin Ng, Jianbiao Zhou, Ling Zhi Wang, John Shyi Peng Yuen, Henry Sun Sien Ho, Sim Mei Yi, Edmund Chiong, Su Pin Choo, Joanne Ngeow, Matthew Chau Hsien Ng, Clarinda Chua, Eugene Shen Ann Yeo, Iain Bee Huat Tan, Joel Xuan En Sng, Nicholas Yan Zhi Tan, Jean Paul Thiery, Boon Cher Goh, Qi Zeng

Nat Commun. 2019; 10: 2484. Published online 2019 Jun 6. doi: 10.1038/s41467-019-10127-x

Correction in:: Nat Commun. 2021; 12: 6431.

PMCID:: PMC6554295

Abstract Article PDF–4.4M

Select item 642673015.

PRL-3和RhoC在A549细胞中的表达及意义

张平, 张志培, 李香敏, 雷杰, 苏凯, 李小飞, 王小平

Zhongguo Fei Ai Za Zhi. 2010 Dec 20; 13(12): 1160–1164. Chinese. doi: 10.3779/j.issn.1009-3419.2010.12.15

PMCID:: PMC6426730

Abstract Article PDF–908K

Select item 639572316.

Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2

Laura Duciel, Océane Anezo, Kalpana Mandal, Cécile Laurent, Nathalie Planque, Frédéric M. Coquelle, David Gentien, Jean-Baptiste Manneville, Simon Saule

Sci Rep. 2019; 9: 2990. Published online 2019 Feb 28. doi: 10.1038/s41598-019-39643-y

PMCID:: PMC6395723

Abstract Article PDF–2.6M

Select item 624383317.

Up-Regulation of Phosphatase in Regenerating Liver-3 (PRL-3) Contributes to Malignant Progression of Hepatocellular Carcinoma by Activating Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN)/Phosphoinositide 3-Kinase (PI3K)/AKT Signaling Pathway

Bing-Hui Li, Yang Wang, Chao-Yang Wang, Ming-Juan Zhao, Tong Deng, Xue-Qun Ren

Med Sci Monit. 2018; 24: 8105–8114. Published online 2018 Nov 12. doi: 10.12659/MSM.913307

PMCID:: PMC6243833

Abstract Article PDF–710K

Select item 585816518.

PRL-3 is a potential glioblastoma prognostic marker and promotes glioblastoma progression by enhancing MMP7 through the ERK and JNK pathways

Nan Mu, Jintao Gu, Nannan Liu, Xiaochang Xue, Zhen Shu, Kuo Zhang, Tonglie Huang, Chu Chu, Wangqian Zhang, Li Gong, Huadong Zhao, Bo Jia, Dakuan Gao, Lei Shang, Wei Zhang, Qingdong Guo

Theranostics. 2018; 8(6): 1527–1539. Published online 2018 Feb 7. doi: 10.7150/thno.22699

PMCID:: PMC5858165

Abstract Article PDF–3.6M

Select item 574137119.

PRL-3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients

Donna R. Edwards, Krzysztof Moroz, Haitao Zhang, David Mulholland, Asim B. Abdel-Mageed, Debasis Mondal

Int J Oncol. 2018 Feb; 52(2): 402–412. Published online 2017 Nov 20. doi: 10.3892/ijo.2017.4208

PMCID:: PMC5741371

Abstract Article PDF–1.3M

Select item 570870920.

Expression of phosphatase of regenerating liver (PRL)-3, is independently associated with biochemical failure, clinical failure and death in prostate cancer

Sigve Andersen, Elin Richardsen, Mehrdad Rakaee, Helena Bertilsson, Roy Bremnes, Magne Børset, Lill-Tove Busund, Tobias Slørdahl

PLoS One. 2017; 12(11): e0189000. Published online 2017 Nov 30. doi: 10.1371/journal.pone.0189000

PMCID:: PMC5708709

Abstract Article PDF–8.0M

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