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Select item 108828071.

Hsa_circ_0005397 promotes hepatocellular carcinoma progression through EIF4A3

Liu-Xia Yuan, Mei Luo, Ruo-Yu Liu, Hui-Xuan Wang, Lin-Ling Ju, Feng Wang, Ya-Li Cao, Zhong-Cheng Wang, Lin Chen

BMC Cancer. 2024; 24: 239. Published online 2024 Feb 21. doi: 10.1186/s12885-024-11984-6

PMCID:: PMC10882807

Abstract Article PDF–2.3M

Select item 108508182.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 107649583.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 106390494.

An interaction between eIF4A3 and eIF3g drives the internal initiation of translation

Jeeyoon Chang, Min-Kyung Shin, Joori Park, Hyun Jung Hwang, Nicolas Locker, Junhak Ahn, Doyeon Kim, Daehyun Baek, Yeonkyoung Park, Yujin Lee, Sung Ho Boo, Hyeong-In Kim, Yoon Ki Kim

Nucleic Acids Res. 2023 Nov 10; 51(20): 10950–10969. Published online 2023 Oct 9. doi: 10.1093/nar/gkad763

PMCID:: PMC10639049

Abstract Article PDF–3.0M

Select item 106176735.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 103204736.

EIF4A3 Acts on the PI3K–AKT–ERK1/2–P70S6K Pathway through FLOT1 to Influence the Development of Lung Adenocarcinoma

Wenhao Yu, Jinghui Liang, Tao Fang, Jin Jiang, Renchang Zhao, Rongyang Li, Jingyi Han, Hui Tian

Mol Cancer Res. 2023 Jul 5; 21(7): 713–725. Published online 2023 Apr 3. doi: 10.1158/1541-7786.MCR-22-0984

PMCID:: PMC10320473

Abstract Article PDF–34M

Select item 102735077.

Eukaryotic initiation factor 4 A-3 promotes glioblastoma growth and invasion through the Notch1-dependent pathway

Lei Wei, Mika Pan, Qiulan Jiang, Beiquan Hu, Jianyi Zhao, Chun Zou, Liechun Chen, Chunhai Tang, Donghua Zou

BMC Cancer. 2023; 23: 550. Published online 2023 Jun 15. doi: 10.1186/s12885-023-10946-8

PMCID:: PMC10273507

Abstract Article PDF–7.5M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101829449.

EIF4A3-induced circular RNA SCAP facilitates tumorigenesis and progression of non-small-cell lung cancer via miR-7/SMAD2 signaling

Yingqing Zhang, Weibo Qi, Yonglei Wu

Environ Sci Pollut Res Int. 2023; 30(24): 65237–65249. Published online 2023 Apr 20. doi: 10.1007/s11356-023-26307-8

PMCID:: PMC10182944

Abstract Article PDF–6.6M

Select item 1017406210.

EIF4A3 serves as a prognostic and immunosuppressive microenvironment factor and inhibits cell apoptosis in bladder cancer

Bing Hu, Ru Chen, Ming Jiang, Situ Xiong, Xiaoqiang Liu, Bin Fu

PeerJ. 2023; 11: e15309. Published online 2023 May 8. doi: 10.7717/peerj.15309

PMCID:: PMC10174062

Abstract Article PDF–8.7M

Select item 1015862411.

The RNA‐binding protein Snd1/Tudor‐SN regulates hypoxia‐responsive gene expression

Juha Saarikettu, Saara Lehmusvaara, Marko Pesu, Ilkka Junttila, Juha Partanen, Petra Sipilä, Matti Poutanen, Jie Yang, Teemu Haikarainen, Olli Silvennoinen

FASEB Bioadv. 2023 May; 5(5): 183–198. Published online 2023 Feb 21. doi: 10.1096/fba.2022-00115

PMCID:: PMC10158624

Abstract Article PDF–7.2M

Select item 997294512.

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang

J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22

PMCID:: PMC9972945

Abstract Article PDF–3.0M

Select item 995044713.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 992534414.

EIF4A3 stabilizes the expression of lncRNA AGAP2‐AS1 to activate cancer‐associated fibroblasts via MyD88/NF‐κb signaling

Qingqing Xu, Tingting Zhao, Honghao Han, Jiahao Fan, Weiping Xie

Thorac Cancer. 2023 Feb; 14(5): 450–461. Published online 2022 Dec 21. doi: 10.1111/1759-7714.14762

PMCID:: PMC9925344

Abstract Article PDF–4.8M

Select item 979798815.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 970808616.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 970377517.

EIF4A3-induced circBRWD3 promotes tumorigenesis of breast cancer through miR-142-3p_miR-142-5p/RAC1/PAK1 signaling

Xianguo Meng, Wei Li, Ziqi Meng, Yan Li

BMC Cancer. 2022; 22: 1225. Published online 2022 Nov 28. doi: 10.1186/s12885-022-10200-7

PMCID:: PMC9703775

Abstract Article PDF–9.2M

Select item 968461718.

Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing

Juan L. López‐Cánovas, Natalia Hermán‐Sánchez, Maria Trinidad Moreno‐Montilla, Mercedes del Rio‐Moreno, Emilia Alors‐Perez, Marina E. Sánchez‐Frias, Víctor Amado, Rubén Ciria, Javier Briceño, Manuel de la Mata, Justo P. Castaño, Manuel Rodriguez‐Perálvarez, Raúl M. Luque, Manuel D. Gahete

Clin Transl Med. 2022 Nov; 12(11): e1102. Published online 2022 Nov 23. doi: 10.1002/ctm2.1102