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Select item 111592491.

Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4

Akio Takehara, Hidetoshi Eguchi, Hiroaki Ohigashi, Osamu Ishikawa, Tsutomu Kasugai, Masayo Hosokawa, Toyomasa Katagiri, Yusuke Nakamura, Hidewaki Nakagawa

Cancer Sci. 2006 Nov; 97(11): 1191–1197. Published online 2006 Aug 21. doi: 10.1111/j.1349-7006.2006.00297.x

PMCID:: PMC11159249

Abstract Article PDF–290K

Select item 111586112.

Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer

Shinya Ohara, Naohide Oue, Akio Matsubara, Koji Mita, Yasuhisa Hasegawa, Tetsutaro Hayashi, Tsuguru Usui, Vishwa Jeet Amatya, Yukio Takeshima, Hiroki Kuniyasu, Wataru Yasui

Cancer Sci. 2008 Aug; 99(8): 1570–1577. Published online 2008 Aug 14. doi: 10.1111/j.1349-7006.2008.00846.x

PMCID:: PMC11158611

Abstract Article PDF–600K

Select item 105147553.

Regenerating gene 4 promotes chemoresistance of colorectal cancer by affecting lipid droplet synthesis and assembly

Cong-Yu Zhang, Rui Zhang, Li Zhang, Zi-Mo Wang, Hong-Zhi Sun, Zheng-Guo Cui, Hua-Chuan Zheng

World J Gastroenterol. 2023 Sep 21; 29(35): 5104–5124. Published online 2023 Sep 21. doi: 10.3748/wjg.v29.i35.5104

PMCID:: PMC10514755

Abstract Article PDF–22M

Select item 94439494.

Upregulation of REG IV gene in human intestinal epithelial cells by lipopolysaccharide via downregulation of microRNA‐24

Shin Takasawa, Chikatsugu Tsuchida, Sumiyo Sakuramoto‐Tsuchida, Tomoko Uchiyama, Mai Makino, Akiyo Yamauchi, Asako Itaya‐Hironaka

J Cell Mol Med. 2022 Sep; 26(17): 4710–4720. Published online 2022 Aug 9. doi: 10.1111/jcmm.17498

PMCID:: PMC9443949

Abstract Article PDF–1.1M

Select item 84649935.

Clinicopathological Significance and Prognostic Implications of REG4 Immunohistochemical Expression in Colorectal Cancer

Guhyun Kang, Ilhwan Oh, Jungsoo Pyo, Dongwook Kang, Byoungkwan Son

Medicina (Kaunas) 2021 Sep; 57(9): 938. Published online 2021 Sep 5. doi: 10.3390/medicina57090938

PMCID:: PMC8464993

Abstract Article PDF–1.6M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79132287.

CDX2 and Reg IV expression and correlation in gastric cancer

Dandan Chai, Huifen Du, Kesheng Li, Xueliang Zhang, Xiaoqin Li, Xiaoning Zhao, Xiaowen Lian, Yang Xu

BMC Gastroenterol. 2021; 21: 92. Published online 2021 Feb 27. doi: 10.1186/s12876-021-01678-9

PMCID:: PMC7913228

Abstract Article PDF–4.8M

Select item 76592268.

REG4 contributes to the invasiveness of pancreatic cancer by upregulating MMP‐7 and MMP‐9

Xu‐Jun He, Xiao‐Ting Jiang, Ying‐Yu Ma, Ying‐Jie Xia, Hui‐Ju Wang, Tian‐Pei Guan, Qin‐Shu Shao, Hou‐Quan Tao

Cancer Sci. 2012 Dec; 103(12): 2082–2091. Published online 2012 Oct 30. doi: 10.1111/cas.12018

PMCID:: PMC7659226

Abstract Article PDF–1.3M

Select item 68853609.

Regulation of REG4 Expression and Prediction of 5-Fluorouracil Sensitivity by CDX2 in Ovarian Mucinous Carcinoma

IEMASA KOH, SUGURU NOSAKA, MASAKI SEKINE, JUN SUGIMOTO, EIJI HIRATA, YOSHIKI KUDO

Cancer Genomics Proteomics. 2019 Nov-Dec; 16(6): 481–490. Published online 2019 Nov 3. doi: 10.21873/cgp.20151

PMCID:: PMC6885360

Abstract Article PDF–595K

Select item 649573610.

Reg IV enhances peritoneal metastasis in gastric carcinomas

H. Kuniyasu, N. Oue, T. Sasahira, L. Yi, Y. Moriwaka, T. Shimomoto, K. Fujii, H. Ohmori, W. Yasui

Cell Prolif. 2009 Feb; 42(1): 110–121. Published online 2009 Jan 6. doi: 10.1111/j.1365-2184.2008.00577.x

PMCID:: PMC6495736

Abstract Article PDF–602K

Select item 587048911.

Expression of Reg IV and SOX9 and their correlation in human gastric cancer

Na Zhang, Dandan Chai, Huifen Du, Kesheng Li, Wenguang Xie, Xingwen Li, Rong Yang, Xiaowen Lian, Yang Xu

BMC Cancer. 2018; 18: 344. Published online 2018 Mar 27. doi: 10.1186/s12885-018-4285-x

PMCID:: PMC5870489

Abstract Article PDF–3.5M

Select item 554971312.

Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway

Jiaoyue Jin, Hang Lv, Junzhou Wu, Dan Li, Kaiyan Chen, Fanrong Zhang, Jing Han, Jianguo Feng, Nan Zhang, Herbert Yu, Dan Su, Lisha Ying

Med Sci Monit. 2017; 23: 3715–3721. Published online 2017 Jul 31. doi: 10.12659/MSM.903134

PMCID:: PMC5549713

Abstract Article PDF–1.1M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 505369414.

REG4 promotes peritoneal metastasis of gastric cancer through GPR37

Hexiao Wang, Lei Hu, Mingde Zang, Baogui Zhang, Yantao Duan, Zhiyuan Fan, Jianfang Li, Liping Su, Min Yan, Zhenggang Zhu, Bingya Liu, Qiumeng Yang

Oncotarget. 2016 May 10; 7(19): 27874–27888. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8442

PMCID:: PMC5053694

Abstract Article PDF–5.9M

Select item 479416515.

REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker

Laura Lehtinen, Pia Vesterkvist, Pia Roering, Taina Korpela, Liisa Hattara, Katja Kaipio, John-Patrick Mpindi, Johanna Hynninen, Annika Auranen, Ben Davidson, Caj Haglund, Kristiina Iljin, Seija Grenman, Harri Siitari, Olli Carpen

PLoS One. 2016; 11(3): e0151590. Published online 2016 Mar 16. doi: 10.1371/journal.pone.0151590