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Select item 111632011.

DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis

Julie Sanceau, Lucie Poupel, Camille Joubel, Isabelle Lagoutte, Stefano Caruso, Sandra Pinto, Christèle Desbois-Mouthon, Cécile Godard, Akila Hamimi, Enzo Montmory, Cécile Dulary, Sophie Chantalat, Amélie Roehrig, Kevin Muret, Benjamin Saint-Pierre, Jean-François Deleuze, Sophie Mouillet-Richard, Thierry Forné, Christophe F. Grosset, Jessica Zucman-Rossi, Sabine Colnot, Angélique Gougelet

Mol Ther. 2024 Apr 3; 32(4): 1125–1143. Published online 2024 Feb 3. doi: 10.1016/j.ymthe.2024.01.036

PMCID:: PMC11163201

Abstract Article PDF–6.9M

Select item 111140452.

The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis

Leonidas Benetatos, Eleftheria Hatzimichael, Eric Londin, George Vartholomatos, Phillipe Loher, Isidore Rigoutsos, Evangelos Briasoulis

Cell Mol Life Sci. 2013 Mar; 70(5): 795–814. Published online 2012 Jul 24. doi: 10.1007/s00018-012-1080-8

PMCID:: PMC11114045

Abstract Article PDF–474K

Select item 110409883.

Evaluating the link between DIO3-FA27 promoter methylation, biochemical indices, and heart failure progression

Yan Qi, Xiangchao Meng, Jing Li, Aoyue He, Jie Hao, Xu Zhao, Ruonan Zhao, Rongrong Chen, Rongqiang Zhang

Clin Epigenetics. 2024; 16: 57. Published online 2024 Apr 24. doi: 10.1186/s13148-024-01668-0

PMCID:: PMC11040988

Abstract Article PDF–4.9M

Select item 110149074.

MiRNAs from the Dlk1-Dio3 locus and miR-224/452 cluster contribute to glioblastoma tumor heterogeneity

Christopher M. Smith, Daniel Catchpoole, Gyorgy Hutvagner

Sci Rep. 2024; 14: 8570. Published online 2024 Apr 13. doi: 10.1038/s41598-024-58870-6

PMCID:: PMC11014907

Abstract Article PDF–4.2M

Select item 82987165.

Human placental piwi-interacting RNA transcriptome is characterized by expression from the DLK1-DIO3 imprinted region

Victor D. Martinez, Adam P. Sage, Brenda C. Minatel, Erin A. Marshall, E. Magda Price, Daiana D. Becker-Santos, Wendy P. Robinson, Wan L. Lam

Sci Rep. 2021; 11: 14981. Published online 2021 Jul 22. doi: 10.1038/s41598-021-93885-3

PMCID:: PMC8298716

Abstract Article PDF–1.4M

Select item 82379946.

Deiodinases and the Metabolic Code for Thyroid Hormone Action

Samuel C Russo, Federico Salas-Lucia, Antonio C Bianco

Endocrinology. 2021 Aug; 162(8): bqab059. Published online 2021 Mar 15. doi: 10.1210/endocr/bqab059

PMCID:: PMC8237994

Abstract Article

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76854828.

High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus

Sebastián Gutiérrez-Vega, Axel Armella, Daniela Mennickent, Marco Loyola, Ambart Covarrubias, Bernel Ortega-Contreras, Carlos Escudero, Marcelo Gonzalez, Martín Alcalá, María del Pilar Ramos, Marta Viana, Erica Castro, Andrea Leiva, Enrique Guzmán-Gutiérrez

PLoS One. 2020; 15(11): e0242743. Published online 2020 Nov 24. doi: 10.1371/journal.pone.0242743

PMCID:: PMC7685482

Abstract Article PDF–1.4M

Select item 74314189.

Decreased expression of the thyroid hormone-inactivating enzyme type 3 deiodinase is associated with lower survival rates in breast cancer

Iuri Martin Goemann, Vicente Rodrigues Marczyk, Mariana Recamonde-Mendoza, Simone Magagnin Wajner, Marcia Silveira Graudenz, Ana Luiza Maia

Sci Rep. 2020; 10: 13914. Published online 2020 Aug 17. doi: 10.1038/s41598-020-70892-4

PMCID:: PMC7431418

Abstract Article PDF–1.7M

Select item 677813710.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 621804611.

Deregulation of the imprinted DLK1-DIO3 locus ncRNAs is associated with replicative senescence of human adipose-derived stem cells

Silvia García-López, Carmen Albo-Castellanos, Rocio G. Urdinguio, Susana Cañón, Fátima Sánchez-Cabo, Alberto Martínez-Serrano, Mario F. Fraga, Antonio Bernad

PLoS One. 2018; 13(11): e0206534. Published online 2018 Nov 5. doi: 10.1371/journal.pone.0206534

PMCID:: PMC6218046

Abstract Article PDF–2.1M

Select item 577425312.

The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species

Anne H. van der Spek, Kin Ki Jim, Aldona Karaczyn, Hermina C. van Beeren, Mariëtte T. Ackermans, Veerle M. Darras, Christina M. J. E. Vandenbroucke-Grauls, Arturo Hernandez, Matthijs C. Brouwer, Eric Fliers, Diederik van de Beek, Anita Boelen

Endocrinology. 2018 Feb; 159(2): 826–835. Published online 2017 Nov 24. doi: 10.1210/en.2017-00666

PMCID:: PMC5774253

Abstract Article

Select item 555823813.

Treatment with D3 Removes Amyloid Deposits, Reduces Inflammation, and Improves Cognition in Old AβPP/PS1 Double Transgenic Mice

Thomas van Groen, Inga Kadish, Susanne Aileen Funke, Dirk Bartnik, Dieter Willbold

J Alzheimers Dis. Author manuscript; available in PMC 2017 Aug 16.

Published in final edited form as: J Alzheimers Dis. 2013; 34(3): 609–620. doi: 10.3233/JAD-121792

PMCID:: PMC5558238

Abstract Article PDF–713K

Select item 534836814.

Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome

Katey S.S. Enfield, Victor D. Martinez, Erin A. Marshall, Greg L. Stewart, Sonia H.Y. Kung, Jhon R. Enterina, Wan L. Lam

Oncotarget. 2016 Dec 6; 7(49): 80957–80966. Published online 2016 Nov 5. doi: 10.18632/oncotarget.13133

PMCID:: PMC5348368

Abstract Article PDF–8.4M

Select item 511006315.

Genomic imprinting of DIO3, a candidate gene for the syndrome associated with human uniparental disomy of chromosome 14

Maria Elena Martinez, David F Cox, Brian P Youth, Arturo Hernandez

Eur J Hum Genet. 2016 Nov; 24(11): 1617–1621. Published online 2016 Jun 22. doi: 10.1038/ejhg.2016.66

PMCID:: PMC5110063

Abstract Article PDF–1.0M

Select item 476936416.

The Type 3 Deiodinase Is a Critical Determinant of Appropriate Thyroid Hormone Action in the Developing Testis

M. Elena Martinez, Aldona Karaczyn, J. Patrizia Stohn, William T. Donnelly, Walburga Croteau, Robin P. Peeters, Valerie A. Galton, Douglas Forrest, Donald St. Germain, Arturo Hernandez

Endocrinology. 2016 Mar; 157(3): 1276–1288. Published online 2016 Jan 4. doi: 10.1210/en.2015-1910

PMCID:: PMC4769364

Abstract Article

Select item 406584217.

Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma

Paul N. Valdmanis, Biswajoy Roy-Chaudhuri, Hak Kyun Kim, Leanne C. Sayles, Yanyan Zheng, Chen-Hua Chuang, Deborah R. Caswell, Kirk Chu, Monte M. Winslow, E. Alejandro Sweet-Cordero, Mark A. Kay

Oncogene. Author manuscript; available in PMC 2015 Jul 2.

Published in final edited form as: Oncogene. 2015 Jan 2; 34(1): 94–103. Published online 2013 Dec 9. doi: 10.1038/onc.2013.523

PMCID:: PMC4065842

Abstract Article PDF–1.3M

Select item 319082618.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317664920.

The Thyroid Hormone-Inactivating Type III Deiodinase Is Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Insulin Secretion

Mayrin C. Medina, Judith Molina, Yelena Gadea, Alberto Fachado, Monika Murillo, Gordana Simovic, Antonello Pileggi, Arturo Hernández, Helena Edlund, Antonio C. Bianco

Endocrinology. 2011 Oct; 152(10): 3717–3727. Published online 2011 Aug 9. doi: 10.1210/en.2011-1210

PMCID:: PMC3176649

Abstract Article

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