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Select item 113021471.

Quantitative analysis of the lysine acetylome reveals the role of SIRT3-mediated HSP60 deacetylation in suppressing intracellular Mycobacterium tuberculosis survival

Chuanzhi Zhu, Yuheng Duan, Jing Dong, Hongyan Jia, Lanyue Zhang, Aiying Xing, Zihui Li, Boping Du, Qi Sun, Yinxia Huang, Zongde Zhang, Liping Pan

Microbiol Spectr. 2024 Aug; 12(8): e00749-24. Published online 2024 Jun 25. doi: 10.1128/spectrum.00749-24

PMCID:: PMC11302147

Abstract Article PDF–2.5M

Select item 111137152.

A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels

Alessia Peserico, Fulvio Chiacchiera, Valentina Grossi, Antonio Matrone, Dominga Latorre, Marta Simonatto, Aurora Fusella, James G. Ryall, Lydia W. S. Finley, Marcia C. Haigis, Gaetano Villani, Pier Lorenzo Puri, Vittorio Sartorelli, Cristiano Simone

Cell Mol Life Sci. 2013 Jun; 70(11): 2015–2029. Published online 2013 Jan 3. doi: 10.1007/s00018-012-1244-6

PMCID:: PMC11113715

Abstract Article PDF–1.3M

Select item 109811573.

Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway

Wei Yang, Chen Qiu, Hongbin Lv, Zhiru Zhang, Tianyu Yao, Li Huang, Guihong Wu, Xueqin Zhang, Jie Chen, Yue He

Transl Vis Sci Technol. 2024 Mar; 13(3): 19. Published online 2024 Mar 22. doi: 10.1167/tvst.13.3.19

PMCID:: PMC10981157

Abstract Article PDF–1.3M

Select item 109665444.

Role of Argininosuccinate Synthase 1 ‐Dependent L‐Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis

Xiaoyun Cao, Vivian Wei Yan Wu, Yumeng Han, Huiling Hong, Yalan Wu, Alice Pik Shan Kong, Kathy O Lui, Xiao Yu Tian

Adv Sci (Weinh) 2024 Mar; 11(12): 2307256. Published online 2024 Jan 17. doi: 10.1002/advs.202307256

PMCID:: PMC10966544

Abstract Article PDF–8.6M

Select item 108911325.

Targeting SIRT3 sensitizes glioblastoma to ferroptosis by promoting mitophagy and inhibiting SLC7A11

Xiaohe Li, Wenlong Zhang, Zhengcao Xing, Shuming Hu, Geqiang Zhang, Tiange Wang, Tianshi Wang, Qiuju Fan, Guoqiang Chen, Jinke Cheng, Xianguo Jiang, Rong Cai

Cell Death Dis. 2024 Feb; 15(2): 168. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06558-0

PMCID:: PMC10891132

Abstract Article PDF–7.1M

Select item 108599676.

SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process

Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai

J Med Chem. 2024 Feb 8; 67(3): 1662–1689. Published online 2024 Jan 23. doi: 10.1021/acs.jmedchem.3c01979

PMCID:: PMC10859967

Abstract Article PDF–11M

Select item 108300867.

Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy

Brittney Poole, Regina Oshins, Zhiguang Huo, Alek Aranyos, Jesse West, Sergio Duarte, Virginia C. Clark, Thiago Beduschi, Ali Zarrinpar, Mark Brantly, Nazli Khodayari

Hepatol Commun. 2024 Feb; 8(2): e0370. Published online 2024 Jan 29. doi: 10.1097/HC9.0000000000000370

Correction in:: Hepatol Commun. 2024 Jun; 8(6): e0439.

PMCID:: PMC10830086

Abstract Article PDF–1.4M

Select item 108154098.

Reduced SIRT1 and SIRT3 and Lower Antioxidant Capacity of Seminal Plasma Is Associated with Shorter Sperm Telomere Length in Oligospermic Men

Varinderpal S. Dhillon, Mohammad Shahid, Permal Deo, Michael Fenech

Int J Mol Sci. 2024 Jan; 25(2): 718. Published online 2024 Jan 5. doi: 10.3390/ijms25020718

PMCID:: PMC10815409

Abstract Article PDF–1.0M

Select item 107611039.

Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation

Zhiya Deng, Man He, Hongbin Hu, Wenqian Zhang, Yaoyuan Zhang, Yue Ge, Tongtong Ma, Jie Wu, Lulan Li, Maomao Sun, Sheng An, Jiaxin Li, Qiaobing Huang, Shenhai Gong, Jiaxing Zhang, Zhongqing Chen, Zhenhua Zeng

Autophagy. 2024; 20(1): 151–165. Published online 2023 Aug 31. doi: 10.1080/15548627.2023.2252265

PMCID:: PMC10761103

Abstract Article PDF–3.9M

Select item 1066630610.

Evaluation of ARK5 and SIRT3 expression in renal cell carcinoma and their clinical significance

Noha Elkady, Amira I. Aldesoky, Marwa Mohammed Dawoud

Diagn Pathol. 2023; 18: 125. Published online 2023 Nov 23. doi: 10.1186/s13000-023-01409-6

PMCID:: PMC10666306

Abstract Article PDF–1.4M

Select item 1063384011.

SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension

Min Li, Lydie Plecitá-Hlavatá, Evgenia Dobrinskikh, B. Alexandre McKeon, Aneta Gandjeva, Suzette Riddle, Aya Laux, Ram Raj Prasad, Sushil Kumar, Rubin M. Tuder, Hui Zhang, Cheng-Jun Hu, Kurt R. Stenmark

Am J Respir Cell Mol Biol. 2023 Nov 1; 69(5): 570–583. Published online 2023 Jun 21. doi: 10.1165/rcmb.2022-0360OC

PMCID:: PMC10633840

Abstract Article PDF–3.0M

Select item 1054861312.

LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter

Meijian Liao, Xiaolin Sun, Wendan Zheng, Mengdi Wu, Yifan Wang, Jia Yao, Yu Ma, Shoucui Gao, Dongsheng Pei

Mol Cancer. 2023; 22: 163. Published online 2023 Oct 4. doi: 10.1186/s12943-023-01859-y

PMCID:: PMC10548613

Abstract Article PDF–12M

Select item 1049781413.

Alterations of SIRT1/SIRT3 subcellular distribution in aging undermine cardiometabolic homeostasis during ischemia and reperfusion

Jingwen Zhang, Hao Wang, Lily Slotabec, Feng Cheng, Yi Tan, Ji Li

Aging Cell. 2023 Sep; 22(9): e13930. Published online 2023 Aug 3. doi: 10.1111/acel.13930

PMCID:: PMC10497814

Abstract Article PDF–9.3M

Select item 1036271414.

SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes

Yanmin Chang, Cailin Wang, Jiahui Zhu, Siyi Zheng, Shangqi Sun, Yanqing Wu, Xingjun Jiang, Lulu Li, Rong Ma, Gang Li

J Transl Med. 2023; 21: 494. Published online 2023 Jul 22. doi: 10.1186/s12967-023-04246-9

PMCID:: PMC10362714

Abstract Article PDF–8.3M

Select item 1033408315.

VNTR Polymorphism in the Intron 5 of SIRT3 and Susceptibility to Breast Cancer

Harshitha Yadav Payavula, Deepika Jamadandu, Salomy Velpula, Raghunadha Rao Digumarti, Vishnupriya Satti, Sandhya Annamaneni

Asian Pac J Cancer Prev. 2023; 24(3): 859–865. doi: 10.31557/APJCP.2023.24.3.859

PMCID:: PMC10334083

Abstract Article PDF–386K

Select item 1023742216.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1021654717.

Role of Sirtuin 3 in Degenerative Diseases of the Central Nervous System

Haofuzi Zhang, Shuhui Dai, Yuefan Yang, Jialiang Wei, Xin Li, Peng Luo, Xiaofan Jiang

Biomolecules. 2023 May; 13(5): 735. Published online 2023 Apr 24. doi: 10.3390/biom13050735

PMCID:: PMC10216547

Abstract Article PDF–2.0M

Select item 1017957618.

Spatiotemporal Coordination of RPE Cell Quality by Extracellular Vesicle miR-494-3p Via Competitive Interplays With SIRT3 or PTEN

Junji Hamuro, Tomoko Yamashita, Yohei Otsuki, Nao Hiramoto, Mayuka Adachi, Takafumi Miyatani, Hiroshi Tanaka, Morio Ueno, Shigeru Kinoshita, Chie Sotozono

Invest Ophthalmol Vis Sci. 2023 May; 64(5): 9. Published online 2023 May 10. doi: 10.1167/iovs.64.5.9