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Select item 110434121.

Endogenous BAX and BAK form mosaic rings of variable size and composition on apoptotic mitochondria

Sarah V. Schweighofer, Daniel C. Jans, Jan Keller-Findeisen, Anne Folmeg, Peter Ilgen, Mark Bates, Stefan Jakobs

Cell Death Differ. 2024 Apr; 31(4): 469–478. Published online 2024 Mar 19. doi: 10.1038/s41418-024-01273-x

PMCID:: PMC11043412

Abstract Article PDF–2.0M

Select item 110227082.

Splicing Factor PQBP1 Curtails BAX Expression to Promote Ovarian Cancer Progression

Xihan Liu, Jiaojiao Zhang, Zixiang Wang, Mingyao Yan, Meining Xu, Gaoyuan Li, Victoria Shender, Jian‐jun Wei, Jianqiao Li, Changshun Shao, Shiqian Zhang, Beihua Kong, Kun Song, Zhaojian Liu

Adv Sci (Weinh) 2024 Apr; 11(15): 2306229. Published online 2024 Feb 11. doi: 10.1002/advs.202306229

PMCID:: PMC11022708

Abstract Article PDF–6.1M

Select item 107987293.

Value of Bax and Bcl2 expression in peripheral blood mononuclear cells for clinical prognosis of patients with chronic heart failure

Yangang Chen, Shuiquan Li, Zhenwen Yang, Tianlu Wang, Fahui Yin, Xiangyu Zhao, Yong Zhang

Medicine (Baltimore) 2024 Jan 19; 103(3): e36943. Published online 2024 Jan 19. doi: 10.1097/MD.0000000000036943

PMCID:: PMC10798729

Abstract Article PDF–763K

Select item 106710374.

Analysis of the Polymorphisms and Expression Levels of the BCL2, BAX and c-MYC Genes in Patients with Ovarian Cancer

Piotr Józef Olbromski, Anna Bogacz, Marta Bukowska, Adam Kamiński, Rafał Moszyński, Piotr Pawlik, Anna Szeliga, Katarzyna Kotrych, Bogusław Czerny

Int J Mol Sci. 2023 Nov; 24(22): 16309. Published online 2023 Nov 14. doi: 10.3390/ijms242216309

PMCID:: PMC10671037

Abstract Article PDF–517K

Select item 106517765.

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Donia M. Moujalled, Fiona C. Brown, Chong Chyn Chua, Michael A. Dengler, Giovanna Pomilio, Natasha S. Anstee, Veronique Litalien, Ella Thompson, Thomas Morley, Sarah MacRaild, Ing S. Tiong, Rhiannon Morris, Karen Dun, Adrian Zordan, Jaynish Shah, Sebastien Banquet, Ensar Halilovic, Erick Morris, Marco J. Herold, Guillaume Lessene, Jerry M. Adams, David C. S. Huang, Andrew W. Roberts, Piers Blombery, Andrew H. Wei

Blood. 2023 Feb 9; 141(6): 634–644. Published online 2022 Oct 14. doi: 10.1182/blood.2022016090

Correction in:: Blood. 2023 Aug 3; 142(5): 494.

PMCID:: PMC10651776

Abstract Article

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102027847.

MicroRNA-431-5p在胃癌组织中低表达：基于线粒体和Bax/Bcl-2/caspase3信号通路

吴佳明, 邓忠权, 朱奕, 窦广健, 李进, 黄立勇

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20; 43(4): 537–543. Chinese. doi: 10.12122/j.issn.1673-4254.2023.04.05

PMCID:: PMC10202784

Abstract Article PDF–1.6M

Select item 101476978.

Dual targeting of BCL-2 and MCL-1 in the presence of BAX breaks venetoclax resistance in human small cell lung cancer

Zsuzsanna Valko, Zsolt Megyesfalvi, Anna Schwendenwein, Christian Lang, Sandor Paku, Nandor Barany, Bence Ferencz, Anita Horvath-Rozsas, Ildiko Kovacs, Erzsebet Schlegl, Veronika Pozonec, Kristiina Boettiger, Melinda Rezeli, Gyorgy Marko-Varga, Ferenc Renyi-Vamos, Mir Alireza Hoda, Thomas Klikovits, Konrad Hoetzenecker, Michael Grusch, Viktoria Laszlo, Balazs Dome, Karin Schelch

Br J Cancer. 2023 May 11; 128(10): 1850–1861. Published online 2023 Mar 14. doi: 10.1038/s41416-023-02219-9

PMCID:: PMC10147697

Abstract Article PDF–1.2M

Select item 98522249.

Mechanisms of MCL-1 protein stability induced by MCL-1 antagonists in B-cell malignancies

Shady I. Tantawy, Aloke Sarkar, Stefan Hubner, Zhi Tan, William G. Wierda, Abdelraouf Eldeib, Shuxing Zhang, Steven Kornblau, Varsha Gandhi

Clin Cancer Res. Author manuscript; available in PMC 2023 Jul 17.

Published in final edited form as: Clin Cancer Res. 2023 Jan 17; 29(2): 446–457. doi: 10.1158/1078-0432.CCR-22-2088

PMCID:: PMC9852224

Abstract Article PDF–2.1M

Select item 984611510.

By modulating miR‐525‐5p/Bax axis, LINC00659 promotes vascular endothelial cell apoptosis

Xizheng Zhu, Beijia Chen, Hui Xu

Immun Inflamm Dis. 2023 Jan; 11(1): e764. Published online 2023 Jan 18. doi: 10.1002/iid3.764

PMCID:: PMC9846115

Abstract Article PDF–1.8M

Select item 965778511.

Deubiquitinating Enzyme USP12 Regulates the Pro-Apoptosis Protein Bax

Hae-Seul Choi, Eun-Su Lim, Kwang-Hyun Baek

Int J Mol Sci. 2022 Nov; 23(21): 13107. Published online 2022 Oct 28. doi: 10.3390/ijms232113107

PMCID:: PMC9657785

Abstract Article PDF–3.9M

Select item 958789312.

Relationship between Bax and Bcl-2 Protein Expression and Outcome of Induction Phase Chemotherapy in Pediatric Acute Lymphoblastic Leukemia

Andi Cahyadi, I Dewa Gede Ugrasena, Mia Ratwita Andarsini, Maria Christina Shanty Larasati, Aryati Aryati, Diah Kusuma Arumsari

Asian Pac J Cancer Prev. 2022 May; 23(5): 1679–1685. doi: 10.31557/APJCP.2022.23.5.1679

PMCID:: PMC9587893

Abstract Article PDF–300K

Select item 954826413.

Evaluation of Bax and BCL 2 Genes Polymorphisms in Iraqi Women with Breast Cancer

Al-Zubaidy H. F. S, Majeed S. R, Al-Koofee D. A. F

Arch Razi Inst. 2022 Apr; 77(2): 799–808. Published online 2022 Apr 30. doi: 10.22092/ARI.2022.357090.1968

PMCID:: PMC9548264

Abstract Article PDF–582K

Select item 947545314.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 943393815.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 903609216.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

Select item 895660417.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 890144118.

The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation

Katia Cosentino, Vanessa Hertlein, Andreas Jenner, Timo Dellmann, Milos Gojkovic, Aida Peña-Blanco, Shashank Dadsena, Noel Wajngarten, John S.H. Danial, Jervis Vermal Thevathasan, Markus Mund, Jonas Ries, Ana J. Garcia-Saez

Mol Cell. 2022 Mar 3; 82(5): 933–949.e9. doi: 10.1016/j.molcel.2022.01.008

PMCID:: PMC8901441

Abstract Article

Select item 889438019.

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing

Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl

Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2