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Items: 1 to 20 of 75

1.
Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization
Francesco Marchesani, Annalisa Michielon, Elisabetta Viale, Annalisa Bianchera, Davide Cavazzini, Loredano Pollegioni, Giulia Murtas, Andrea Mozzarelli, Stefano Bettati, Alessio Peracchi, Barbara Campanini, Stefano Bruno
Biomolecules. 2023 Aug; 13(8): 1219. Published online 2023 Aug 4. doi: 10.3390/biom13081219
PMCID:
PMC10452355
AbstractArticlePDF–2.0M
2.
Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non‐small cell lung carcinoma
Xijuan Peng, Lanfu Zhao, Linong Yao, Jingzhi Dong, Wei Wu, Tao Luo
Thorac Cancer. 2023 Jul; 14(19): 1812–1823. Published online 2023 May 16. doi: 10.1111/1759-7714.14926
PMCID:
PMC10317601
AbstractArticlePDF–5.8M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
5.
L‐serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase
Francesco Marchesani, Erika Zangelmi, Giulia Murtas, Elisa Costanzi, Raheem Ullah, Alessio Peracchi, Stefano Bruno, Loredano Pollegioni, Andrea Mozzarelli, Paola Storici, Barbara Campanini
Protein Sci. 2023 Apr; 32(4): e4609. Published online 2023 Apr 1. doi: 10.1002/pro.4609
PMCID:
PMC10031235
AbstractArticlePDF–7.6M
6.
Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma
Min Wang, Song Yue, Zhu Yang
Sci Rep. 2023; 13: 4081. Published online 2023 Mar 11. doi: 10.1038/s41598-023-31325-0
PMCID:
PMC10008565
AbstractArticlePDF–7.0M
7.
Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant
Jingwen Jiang, Hai-Ning Chen, Ping Jin, Li Zhou, Liyuan Peng, Zhao Huang, Siyuan Qin, Bowen Li, Hui Ming, Maochao Luo, Na Xie, Wei Gao, Edouard C. Nice, Qiang Yu, Canhua Huang
Signal Transduct Target Ther. 2023; 8: 65. Published online 2023 Feb 15. doi: 10.1038/s41392-022-01266-7
PMCID:
PMC9929071
AbstractArticlePDF–7.3M
8.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M
9.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
10.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
11.
Examination of the effects of microRNA-145-5p and phosphoserine aminotransferase 1 in colon cancer
Ruliang Ding, Weiwen Hong, Liang Huang, Jinfan Shao, Wenfeng Yu, Xijuan Xu
Bioengineered. 2022; 13(5): 12794–12806. Published online 2022 May 26. doi: 10.1080/21655979.2022.2071010
PMCID:
PMC9275947
AbstractArticlePDF–2.6M
12.
Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression
Georgina D. Barnabas, Joo Sang Lee, Tamar Shami, Michal Harel, Lir Beck, Michael Selitrennik, Livnat Jerby-Arnon, Neta Erez, Eytan Ruppin, Tamar Geiger
Cancer Res. Author manuscript; available in PMC 2022 Jun 22.
Published in final edited form as: Cancer Res. 2021 Mar 15; 81(6): 1443–1456. Published online 2021 Jan 26. doi: 10.1158/0008-5472.CAN-19-3020
PMCID:
PMC9216326
AbstractArticlePDF–2.6M
13.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
14.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
15.
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway
Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan
J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5
PMCID:
PMC9102726
AbstractArticlePDF–15M
16.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
17.
Tumor suppressor BAP1 nuclear import is governed by transportin-1
Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu
J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094
PMCID:
PMC9036092
AbstractArticlePDF–4.0M
18.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
19.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan
Cell. Author manuscript; available in PMC 2022 Feb 19.
Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041
PMCID:
PMC8857049
AbstractArticlePDF–3.6M
20.
Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors
Bo-Hyun Choi, Vipin Rawat, Jenny Högström, Philippa A. Burns, Kelly O. Conger, Mete Emir Ozgurses, Jaymin M. Patel, Tejas S. Mehta, Angelica Warren, Laura M. Selfors, Taru Muranen, Jonathan L. Coloff
Cell Rep. Author manuscript; available in PMC 2022 Feb 15.
Published in final edited form as: Cell Rep. 2022 Jan 18; 38(3): 110278. doi: 10.1016/j.celrep.2021.110278
PMCID:
PMC8845302
AbstractArticlePDF–2.9M

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