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Select item 111464231.

Macroscopic changes in aquaporin-4 underlie blast traumatic brain injury-related impairment in glymphatic function

Molly Braun, Mathew Sevao, Samantha A Keil, Elizabeth Gino, Marie X Wang, Janet Lee, Mariya A Haveliwala, Emily Klein, Sanjana Agarwal, Taylor Pedersen, C Harker Rhodes, Deidre Jansson, David Cook, Elaine Peskind, Daniel P Perl, Juan Piantino, Abigail G Schindler, Jeffrey J Iliff

Brain. 2024 Jun; 147(6): 2214–2229. Published online 2024 May 28. doi: 10.1093/brain/awae065

PMCID:: PMC11146423

Abstract Article PDF–52M

Select item 111158132.

Differential water permeability and regulation of three aquaporin 4 isoforms

Robert A. Fenton, Hanne B. Moeller, Marina Zelenina, Marteinn T. Snaebjornsson, Torgeir Holen, Nanna MacAulay

Cell Mol Life Sci. 2010 Mar; 67(5): 829–840. Published online 2009 Dec 15. doi: 10.1007/s00018-009-0218-9

PMCID:: PMC11115813

Abstract Article PDF–669K

Select item 109917513.

Differentiated pattern of complement system activation between MOG-IgG-associated disease and AQP4-IgG-positive neuromyelitis optica spectrum disorder

Eun Bin Cho, Ju-Hong Min, Patrick Waters, Miyoung Jeon, Eun-Seon Ju, Ho Jin Kim, Su-Hyun Kim, Ha Young Shin, Sa-Yoon Kang, Young-Min Lim, Sun-Young Oh, Hye Lim Lee, Eunhee Sohn, Sang-Soo Lee, Jeeyoung Oh, Sunyoung Kim, So-Young Huh, Joong-Yang Cho, Jin Myoung Seok, Byung-Jo Kim, Byoung Joon Kim

Front Immunol. 2024; 15: 1320094. Published online 2024 Mar 21. doi: 10.3389/fimmu.2024.1320094

PMCID:: PMC10991751

Abstract Article PDF–1.3M

Select item 109373774.

B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4

Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan P. Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R. Buchholz, Sylvia Heink, Dirk H. Busch, Ludger Klein, Thomas Korn

Nature. 2024; 627(8003): 407–415. Published online 2024 Feb 21. doi: 10.1038/s41586-024-07079-8

PMCID:: PMC10937377

Abstract Article PDF–11M

Select item 108553515.

Aquaporin-4 and Parkinson’s Disease

Ksenia V. Lapshina, Irina V. Ekimova

Int J Mol Sci. 2024 Feb; 25(3): 1672. Published online 2024 Jan 30. doi: 10.3390/ijms25031672

PMCID:: PMC10855351

Abstract Article PDF–856K

Select item 105661846.

Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer’s disease and other proteinopathies

Pablo Mohaupt, Jérôme Vialaret, Christophe Hirtz, Sylvain Lehmann

Alzheimers Res Ther. 2023; 15: 170. Published online 2023 Oct 11. doi: 10.1186/s13195-023-01318-2

PMCID:: PMC10566184

Abstract Article PDF–851K

Select item 104010897.

The effects of AQP4 rs162009 on resting‐state brain activity in Parkinson's disease

Mengze Jiang, Yi Fang, Shaobing Dai, Xiaoli Si, Zhiyun Wang, Jiahui Tang, Ting Gao, Yi Liu, Zhe Song, Jiali Pu, Baorong Zhang

CNS Neurosci Ther. 2023 Sep; 29(9): 2645–2655. Published online 2023 Apr 10. doi: 10.1111/cns.14208

PMCID:: PMC10401089

Abstract Article PDF–3.1M

Select item 103933938.

Aquaporin-4 and GPRC5B: old and new players in controlling brain oedema

Emma M J Passchier, Sven Kerst, Eelke Brouwers, Eline M C Hamilton, Quinty Bisseling, Marianna Bugiani, Quinten Waisfisz, Philip Kitchen, Lucas Unger, Marjolein Breur, Leoni Hoogterp, Sharon I de Vries, Truus E M Abbink, Maarten H P Kole, Rob Leurs, Henry F Vischer, Maria S Brignone, Elena Ambrosini, François Feillet, Alfred P Born, Leon G Epstein, Huibert D Mansvelder, Rogier Min, Marjo S van der Knaap

Brain. 2023 Aug; 146(8): 3444–3454. Published online 2023 May 5. doi: 10.1093/brain/awad146

PMCID:: PMC10393393

Abstract Article PDF–1.1M

Select item 101918429.

Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression

Ran Wang, Lu Peng, Yong Xiao, Qi Zhou, Zhen Wang, Lei Tang, Hong Xiao, Kun Yang, Hongyi Liu, Li Li

Cancer Gene Ther. 2023; 30(5): 716–726. Published online 2023 Jan 4. doi: 10.1038/s41417-022-00582-y

Correction in:: Cancer Gene Ther. 2023; 30(5): 767.

PMCID:: PMC10191842

Abstract Article PDF–27M

Select item 1019049810.

AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Na_v1.6‐Mediated Astrocyte Autophagy

Dan‐Dan Zhu, Yue‐Lin Huang, Song‐Yu Guo, Na Li, Xue‐Wei Yang, Ao‐Ran Sui, Qiong Wu, Yue Zhang, Yue Kong, Qi‐Fa Li, Ting Zhang, Wen‐Fei Zheng, Ai‐Ping Li, Jian Yu, Tong‐Hui Ma, Shao Li

Adv Sci (Weinh) 2023 May; 10(14): 2205862. Published online 2023 Mar 15. doi: 10.1002/advs.202205862

Correction in:: Adv Sci (Weinh). 2023 Oct; 10(30): 2306241.

PMCID:: PMC10190498

Abstract Article PDF–22M

Select item 995355911.

Aquaporin-1 and Aquaporin-4 Expression in Ependyma, Choroid Plexus and Surrounding Transition Zones in the Human Brain

Ronja Bihlmaier, Felix Deffner, Ulrich Mattheus, Peter H. Neckel, Bernhard Hirt, Andreas F. Mack

Biomolecules. 2023 Feb; 13(2): 212. Published online 2023 Jan 22. doi: 10.3390/biom13020212

PMCID:: PMC9953559

Abstract Article PDF–2.1M

Select item 958533612.

Hsa_circ_0079530/AQP4 Axis Is Related to Non-Small Cell Lung Cancer Development and Radiosensitivity

Xianghui Yang, Min Li, Yang Zhao, Xiaolang Tan, Jiqing Su, Xi Zhong

Ann Thorac Cardiovasc Surg. 2022; 28(5): 307–319. Published online 2022 Jul 26. doi: 10.5761/atcs.oa.21-00237

PMCID:: PMC9585336

Abstract Article PDF–8.7M

Select item 949898613.

AQP4, Astrogenesis, and Hydrocephalus: A New Neurological Perspective

Leandro Castañeyra-Ruiz, Ibrahim González-Marrero, Luis G. Hernández-Abad, Seunghyun Lee, Agustín Castañeyra-Perdomo, Michael Muhonen

Int J Mol Sci. 2022 Sep; 23(18): 10438. Published online 2022 Sep 9. doi: 10.3390/ijms231810438

PMCID:: PMC9498986

Abstract Article PDF–1.6M

Select item 920284214.

Aquaporin 4 is not present in normal porcine and human lamina cribrosa

Elizabeth C. Kimball, Sarah Quillen, Mary E. Pease, Casey Keuthan, Aru Nagalingam, Donald J. Zack, Thomas V. Johnson, Harry A. Quigley

PLoS One. 2022; 17(6): e0268541. Published online 2022 Jun 16. doi: 10.1371/journal.pone.0268541

PMCID:: PMC9202842

Abstract Article PDF–4.7M

Select item 913862015.

The Readthrough Isoform AQP4ex Is Constitutively Phosphorylated in the Perivascular Astrocyte Endfeet of Human Brain

Roberta Pati, Claudia Palazzo, Onofrio Valente, Pasqua Abbrescia, Raffaella Messina, Nicoletta Concetta Surdo, Konstantinos Lefkimmiatis, Francesco Signorelli, Grazia Paola Nicchia, Antonio Frigeri

Biomolecules. 2022 May; 12(5): 633. Published online 2022 Apr 25. doi: 10.3390/biom12050633

PMCID:: PMC9138620

Abstract Article PDF–2.0M

Select item 903058116.

Aquaporin-4 in Neuromyelitis Optica Spectrum Disorders: A Target of Autoimmunity in the Central Nervous System

Yoichiro Abe, Masato Yasui

Biomolecules. 2022 Apr; 12(4): 591. Published online 2022 Apr 17. doi: 10.3390/biom12040591

PMCID:: PMC9030581

Abstract Article PDF–1.5M

Select item 896217617.

AQP4 labels a subpopulation of white matter-dependent glial radial cells affected by pediatric hydrocephalus, and its expression increased in glial microvesicles released to the cerebrospinal fluid in obstructive hydrocephalus

Leandro Castañeyra-Ruiz, Ibrahim González-Marrero, Luis G. Hernández-Abad, Emilia M. Carmona-Calero, Marta R. Pardo, Rebeca Baz-Davila, Seunghyun Lee, Michael Muhonen, Ricardo Borges, Agustín Castañeyra-Perdomo

Acta Neuropathol Commun. 2022; 10: 41. Published online 2022 Mar 28. doi: 10.1186/s40478-022-01345-4

PMCID:: PMC8962176

Abstract Article PDF–4.0M

Select item 893538718.

TNF-α induces AQP4 overexpression in astrocytes through the NF-κB pathway causing cellular edema and apoptosis

Hong Lu, Li Ai, Baoyue Zhang

Biosci Rep. 2022 Mar 31; 42(3): BSR20212224. Published online 2022 Mar 17. doi: 10.1042/BSR20212224

PMCID:: PMC8935387

Abstract Article PDF–1.2M

Select item 885892419.

Alteration of the translational readthrough isoform AQP4ex induces redistribution and downregulation of AQP4 in human glioblastoma

Onofrio Valente, Raffaella Messina, Giuseppe Ingravallo, Emilio Bellitti, Domenico Sergio Zimatore, Luigi de Gennaro, Pasqua Abbrescia, Roberta Pati, Claudia Palazzo, Grazia Paola Nicchia, Maria Trojano, Francesco Signorelli, Antonio Frigeri

Cell Mol Life Sci. 2022 Mar; 79(3): 140. Published online 2022 Feb 20. doi: 10.1007/s00018-021-04123-y

PMCID:: PMC8858924

Abstract Article PDF–2.7M

Select item 883563720.

Disassembly and Mislocalization of AQP4 in Incipient Scar Formation after Experimental Stroke

Shervin Banitalebi, Nadia Skauli, Samuel Geiseler, Ole Petter Ottersen, Mahmood Amiry-Moghaddam

Int J Mol Sci. 2022 Feb; 23(3): 1117. Published online 2022 Jan 20. doi: 10.3390/ijms23031117

PMCID:: PMC8835637

Abstract Article PDF–8.7M

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