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Items: 1 to 20 of 77

1.
Negative regulation of SH2B3 by SMYD5 controls epithelial-mesenchymal transition in lung cancer
In Hwan Tae, Tae Young Ryu, Yunsang Kang, Jinkwon Lee, Kwanho Kim, Jeong Min Lee, Hee-Won Kim, Jung Heon Ko, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho
Mol Cells. 2024 May; 47(5): 100067. Published online 2024 May 7. doi: 10.1016/j.mocell.2024.100067
PMCID:
PMC11143772
AbstractArticlePDF–6.3M
2.
CTLA4, SH2B3, and CLEC16A diversely affect the progression of early islet autoimmunity in relatives of Type 1 diabetes patients
Julie Vandewalle, Aster K Desouter, Bart J Van der Auwera, Sylvie Tenoutasse, Pieter Gillard, Christophe De Block, Bart Keymeulen, Frans K Gorus, Mark Van de Casteele, the Belgian Diabetes Registry
Clin Exp Immunol. 2023 Mar; 211(3): 224–232. Published online 2023 Jan 9. doi: 10.1093/cei/uxad002
PMCID:
PMC10038324
AbstractArticlePDF–329K
3.
HDAC6 regulates human erythroid differentiation through modulation of JAK2 signalling
Pascal Vong, Kahia Messaoudi, Nicolas Jankovsky, Cathy Gomilla, Yohann Demont, Alexis Caulier, Guillaume Jedraszak, Julien Demagny, Stefan Djordjevic, Thomas Boyer, Jean Pierre Marolleau, Jacques Rochette, Hakim Ouled‐Haddou, Loïc Garçon
J Cell Mol Med. 2023 Jan; 27(2): 174–188. Published online 2022 Dec 28. doi: 10.1111/jcmm.17559
PMCID:
PMC9843532
AbstractArticlePDF–2.1M
4.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
5.
The autoimmune risk R262W variant of the adaptor SH2B3 improves survival in sepsis
Eric J. Allenspach, Nicholas J. Shubin, Karen Cerosaletti, Carmen Mikacenic, Jacquelyn A Gorman, Matthew A. MacQuivey, Aaron B.I. Rosen, Andrew E. Timms, Michelle N. Wray-Dutra, Kerri Niino, Denny Liggitt, Mark M. Wurfel, Jane H. Buckner, Adrian M. Piliponsky, David J. Rawlings
J Immunol. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: J Immunol. 2021 Dec 1; 207(11): 2710–2719. Published online 2021 Nov 5. doi: 10.4049/jimmunol.2100454
PMCID:
PMC8612972
AbstractArticlePDF–2.5M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
LNK promotes granulosa cell apoptosis in PCOS via negatively regulating insulin-stimulated AKT-FOXO3 pathway
Min Tan, Yanxiang Cheng, Xiaozhu Zhong, Dongyong Yang, Sushi Jiang, Yang Ye, Miao Ding, Guijun Guan, Dongzi Yang, Xiaomiao Zhao
Aging (Albany NY) 2021 Feb 15; 13(3): 4617–4633. Published online 2021 Jan 20. doi: 10.18632/aging.202421
PMCID:
PMC7906173
AbstractArticlePDF–1.2M
8.
The Longevity-Associated SH2B3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects
Chia-Ling Kuo, Micaella Joaquim, George A Kuchel, Luigi Ferrucci, Lorna W Harries, Luke C Pilling, David Melzer
J Gerontol A Biol Sci Med Sci. 2020 Sep; 75(9): 1656–1662. Published online 2019 Aug 20. doi: 10.1093/gerona/glz191
Correction in:
J Gerontol A Biol Sci Med Sci. 2020 Sep; 75(9): 1686.
PMCID:
PMC7749196
AbstractArticlePDF–452K
9.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
10.
SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain
Paul B. Sinclair, Sarra Ryan, Matthew Bashton, Shaun Hollern, Rebecca Hanna, Marian Case, Edward C. Schwalbe, Claire J. Schwab, Ruth E. Cranston, Brian D. Young, Julie A. E. Irving, Ajay J. Vora, Anthony V. Moorman, Christine J. Harrison
Leukemia. 2019; 33(8): 1881–1894. Published online 2019 Feb 28. doi: 10.1038/s41375-019-0412-1
PMCID:
PMC6756024
AbstractArticlePDF–2.8M
11.
Combined Analysis of Methylation and Gene Expression Profiles in Separate Compartments of Small Bowel Mucosa Identified Celiac Disease Patients’ Signatures
D. Cielo, M. Galatola, N. Fernandez-Jimenez, L. De Leo, K. Garcia-Etxebarria, C. Loganes, A. Tommasini, T. Not, R. Auricchio, L. Greco, J. R. Bilbao
Sci Rep. 2019; 9: 10020. Published online 2019 Jul 10. doi: 10.1038/s41598-019-46468-2
PMCID:
PMC6620355
AbstractArticlePDF–2.1M
12.
LNK suppresses interferon signaling in melanoma
Ling-Wen Ding, Qiao-Yang Sun, Jarem J. Edwards, Lucia Torres Fernández, Xue-Bin Ran, Si-Qin Zhou, Richard A. Scolyer, James S. Wilmott, John F. Thompson, Ngan Doan, Jonathan W. Said, Nachiyappan Venkatachalam, Jin-Fen Xiao, Xin-Yi Loh, Maren Pein, Liang Xu, David W. Mullins, Henry Yang, De-Chen Lin, H. Phillip Koeffler
Nat Commun. 2019; 10: 2230. Published online 2019 May 20. doi: 10.1038/s41467-019-09711-y
PMCID:
PMC6527565
AbstractArticlePDF–2.9M
13.
Epigenetic Modifications in Placenta are Associated with the Child's Sensitization to Allergens
Hani Harb, Bilal Alashkar Alhamwe, Nathalie Acevedo, Paolo Frumento, Catharina Johansson, Lisa Eick, Nikos Papadogiannakis, Johan Alm, Harald Renz, Daniel P. Potaczek, Annika Scheynius
Biomed Res Int. 2019; 2019: 1315257. Published online 2019 Apr 17. doi: 10.1155/2019/1315257
PMCID:
PMC6500694
AbstractArticlePDF–1.0M
14.
The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination
Ryan Donaghy, Xu Han, Krasimira Rozenova, Kaosheng Lv, Qinqin Jiang, Miriam Doepner, Roger A. Greenberg, Wei Tong
Blood. 2019 Apr 4; 133(14): 1560–1571. Prepublished online 2019 Feb 12. doi: 10.1182/blood-2018-10-877563
PMCID:
PMC6450430
AbstractArticle
15.
Evidence for a Causal Role of the SH2B3-β2M Axis in Blood Pressure Regulation: the Framingham Heart Study
Joshua A. KEEFE, Shih-Jen HWANG, Tianxiao HUAN, Michael MENDELSON, Chen YAO, Paul COURCHESNE, Mohamed A. SALEH, Meena S. MADHUR, Daniel LEVY
Hypertension. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: Hypertension. 2019 Feb; 73(2): 497–503. doi: 10.1161/HYPERTENSIONAHA.118.12094
PMCID:
PMC6334659
AbstractArticlePDF–667K
16.
Role of SH2B3 R262W gene polymorphism and risk of coronary heart disease: A PRISMA-compliant meta-analysis
Lu Hong, Yu-Feng Jiang, Min Chen, Nan-Nan Zhang, Hua-Jia Yang, Qing Rui, Ya-Feng Zhou
Medicine (Baltimore) 2018 Nov; 97(48): e13436. Published online 2018 Nov 30. doi: 10.1097/MD.0000000000013436
PMCID:
PMC6283144
AbstractArticlePDF–1.0M
17.
LNK deficiency promotes acute aortic dissection and rupture
Fanny Laroumanie, Arina Korneva, Matthew R. Bersi, Matthew R. Alexander, Liang Xiao, Xue Zhong, Justin P. Van Beusecum, Yuhan Chen, Mohamed A. Saleh, William G. McMaster, Kyle A. Gavulic, Bethany L. Dale, Shilin Zhao, Yan Guo, Yu Shyr, Daniel S. Perrien, Nancy J. Cox, John A. Curci, Jay D. Humphrey, Meena S. Madhur
JCI Insight. 2018 Oct 18; 3(20): e122558. Published online 2018 Oct 18. doi: 10.1172/jci.insight.122558
PMCID:
PMC6237478
AbstractArticlePDF–2.2M
18.
Co-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunction
Zheng Ge, Yan Gu, Lichan Xiao, Qi Han, Jianyong Li, Baoan Chen, James Yu, Yuka Imamura Kawasawa, Kimberly J. Payne, Sinisa Dovat, Chunhua Song
Oncotarget. 2016 Jul 19; 7(29): 46014–46027. Published online 2016 Jun 14. doi: 10.18632/oncotarget.10014
PMCID:
PMC5216778
AbstractArticlePDF–8.7M
19.
Overexpression of Lnk in the Ovaries Is Involved in Insulin Resistance in Women With Polycystic Ovary Syndrome
Meihua Hao, Feng Yuan, Chenchen Jin, Zehong Zhou, Qi Cao, Ling Xu, Guanlei Wang, Hui Huang, Dongzi Yang, Meiqing Xie, Xiaomiao Zhao
Endocrinology. 2016 Oct; 157(10): 3709–3718. Published online 2016 Jul 26. doi: 10.1210/en.2016-1234
PMCID:
PMC5045500
AbstractArticle
20.
LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis
Wei Wang, Yang Tang, Ying Wang, Liana Tascau, Joanna Balcerek, Wei Tong, Ross L. Levine, Carrie Welch, Alan R. Tall, Nan Wang
Circ Res. Author manuscript; available in PMC 2017 Sep 2.
Published in final edited form as: Circ Res. 2016 Sep 2; 119(6): e91–e103. Published online 2016 Jul 18. doi: 10.1161/CIRCRESAHA.116.308955
PMCID:
PMC5016083
AbstractArticlePDF–1.3M

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