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Select item 95329081.

Effects of α5 GABA_A receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease

Jovana Aranđelović, Anja Santrač, Bojan Batinić, Lidija Todorović, Vladimir Stevanović, Veera Venkata Naga Phani Babu Tiruveedhula, Dishary Sharmin, Farjana Rashid, Boban Stanojević, James M. Cook, Miroslav M. Savić

CNS Neurosci Ther. 2022 Nov; 28(11): 1767–1778. Published online 2022 Jul 13. doi: 10.1111/cns.13914

PMCID:: PMC9532908

Abstract Article PDF–4.2M

Select item 84475202.

An association study in the Taiwan Biobank elicits the GABAA receptor genes GABRB3, GABRA5, and GABRG3 as candidate loci for sleep duration in the Taiwanese population

Sheue-Jane Hou, Shih-Jen Tsai, Po-Hsiu Kuo, Wan-Yu Lin, Yu-Li Liu, Albert C. Yang, Eugene Lin, Tsuo-Hung Lan

BMC Med Genomics. 2021; 14: 223. Published online 2021 Sep 16. doi: 10.1186/s12920-021-01083-x

PMCID:: PMC8447520

Abstract Article PDF–811K

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 70185854.

Sex Differences in the Expression of the α5 Subunit of the GABA_A Receptor in Alcoholics with and without Cirrhosis of the Liver

Paulina Janeczek, Natalie Colson, Peter R. Dodd, Joanne M. Lewohl

Alcohol Clin Exp Res. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Alcohol Clin Exp Res. 2020 Feb; 44(2): 423–434. Published online 2020 Jan 9. doi: 10.1111/acer.14266

PMCID:: PMC7018585

Abstract Article PDF–1.4M

Select item 65986345.

Altered inhibitory synapses in de novo GABRA5 and GABRA1 mutations associated with early onset epileptic encephalopathies

Ciria C Hernandez, Wenshu XiangWei, Ningning Hu, Dingding Shen, Wangzhen Shen, Andre H Lagrange, Yujia Zhang, Lifang Dai, Changhong Ding, Zhaohui Sun, Jiasheng Hu, Hongmin Zhu, Yuwu Jiang, Robert L Macdonald

Brain. 2019 Jul; 142(7): 1938–1954. Published online 2019 May 5. doi: 10.1093/brain/awz123

PMCID:: PMC6598634

Abstract Article PDF–1.3M

Select item 61234836.

Cryo-EM structure of the human α5β3 GABA_A receptor

Si Liu, Lingyi Xu, Fenghui Guan, Yun-Tao Liu, Yanxiang Cui, Qing Zhang, Xiang Zheng, Guo-Qiang Bi, Z. Hong Zhou, Xiaokang Zhang, Sheng Ye

Cell Res. 2018 Sep; 28(9): 958–961. Published online 2018 Aug 23. doi: 10.1038/s41422-018-0077-8

PMCID:: PMC6123483

Article PDF–1.0M

Select item 60616927.

De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy

Kameryn M Butler, Olivia A Moody, Elisabeth Schuler, Jason Coryell, John J Alexander, Andrew Jenkins, Andrew Escayg

Brain. 2018 Aug; 141(8): 2392–2405. Published online 2018 Jun 28. doi: 10.1093/brain/awy171

PMCID:: PMC6061692

Abstract Article PDF–820K

Select item 59637838.

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABA_A receptors involved in volume regulation

Camiel L. C. Wielders, Pim van Nierop, Tinke L. Vormer, Floris Foijer, Joanne Verheij, Johannes C. Lodder, Jesper B. Andersen, Huibert D. Mansvelder, Hein te Riele

PLoS One. 2018; 13(5): e0196979. Published online 2018 May 22. doi: 10.1371/journal.pone.0196979

PMCID:: PMC5963783

Abstract Article PDF–7.6M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 546825010.

GABA_A receptor subunit gene polymorphisms predict symptom-based and developmental deficits in Chinese Han children and adolescents with autistic spectrum disorders

Shuhan Yang, Xuan Guo, Xiaopeng Dong, Yu Han, Lei Gao, Yuanyuan Su, Wei Dai, Xin Zhang

Sci Rep. 2017; 7: 3290. Published online 2017 Jun 12. doi: 10.1038/s41598-017-03666-0

PMCID:: PMC5468250

Abstract Article PDF–1.2M

Select item 524047711.

Synaptic Localization of α5 GABA (A) Receptors via Gephyrin Interaction Regulates Dendritic Outgrowth and Spine Maturation

Megan L. Brady, Tija C. Jacob

Dev Neurobiol. Author manuscript; available in PMC 2017 Jan 17.

Published in final edited form as: Dev Neurobiol. 2015 Nov; 75(11): 1241–1251. Published online 2015 Feb 18. doi: 10.1002/dneu.22280

PMCID:: PMC5240477

Abstract Article PDF–1.8M

Select item 486296212.

Using [¹¹C]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism

Anne Lingford-Hughes, James Myers, Ben Watson, Alastair G. Reid, Nicola Kalk, Adrian Feeney, Alexander Hammers, Daniela A. Riaño-Barros, Colm J. McGinnity, Lindsay G. Taylor, Lula Rosso, David J. Brooks, Federico Turkheimer, David J. Nutt

Neuroimage. 2016 May 15; 132: 1–7. doi: 10.1016/j.neuroimage.2016.02.005

PMCID:: PMC4862962

Abstract Article

Select item 455434513.

HIV-1 Subtypes B and C Tat Differentially Impact Synaptic Plasticity Expression and Implicates HIV-Associated Neurocognitive Disorders

Thangavel Samikkannu, Venkata S.R. Atluri, Adriana Y. Arias, Kesava V.K. Rao, Carmen T. Mulet, Rahul D. Jayant, Madhavan P.N. Nair

Curr HIV Res. Author manuscript; available in PMC 2015 Aug 31.

Published in final edited form as: Curr HIV Res. 2014; 12(6): 397–405. doi: 10.2174/1570162x13666150121104720

PMCID:: PMC4554345

Abstract Article PDF–1.5M

Select item 452480114.

Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia

Greg C. Bristow, John A. Bostrom, Vahram Haroutunian, Monsheel S. Sodhi

Schizophr Res. Author manuscript; available in PMC 2016 Sep 1.

Published in final edited form as: Schizophr Res. 2015 Sep; 167(0): 57–63. Published online 2015 Feb 7. doi: 10.1016/j.schres.2015.01.025

PMCID:: PMC4524801

Abstract Article PDF–764K

Select item 448961715.

The brain GABA-benzodiazepine receptor alpha-5 subtype in autism spectrum disorder: A pilot [¹¹C]Ro15-4513 positron emission tomography study

Maria Andreina Mendez, Jamie Horder, Jim Myers, Suzanne Coghlan, Paul Stokes, David Erritzoe, Oliver Howes, Anne Lingford-Hughes, Declan Murphy, David Nutt

Neuropharmacology. Author manuscript; available in PMC 2015 Jul 2.

Published in final edited form as: Neuropharmacology. 2013 May; 68: 195–201. Published online 2012 Apr 21. doi: 10.1016/j.neuropharm.2012.04.008

PMCID:: PMC4489617

Article PDF–1.0M

Select item 423765416.

Enhancement of α5-Containing Gamma-Aminobutyric Acid TypeAReceptors by the Nonimmobilizer 1,2-Dichlorohexafluorocyclobutane (F6) is Abolished by the β3(N265M) Mutation

Paul M. Burkat, Chong Lor, Misha Perouansky, Robert A. Pearce

Anesth Analg. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Anesth Analg. 2014 Dec; 119(6): 1277–1284. doi: 10.1213/ANE.0000000000000423

PMCID:: PMC4237654

Abstract Article PDF–506K

Select item 413875417.

Evidence for Linkage and Association of GABRB3 and GABRA5 to Panic Disorder

Laura M Hodges, Abby J Fyer, Myrna M Weissman, Mark W Logue, Fatemeh Haghighi, Oleg Evgrafov, Allessandro Rotondo, James A Knowles, Steven P Hamilton

Neuropsychopharmacology. 2014 Sep; 39(10): 2423–2431. Prepublished online 2014 May 23. Published online 2014 Jun 11. doi: 10.1038/npp.2014.92

PMCID:: PMC4138754

Abstract Article PDF–490K

Select item 396709618.

Strong genetic evidence for a selective influence of GABA_A receptors on a component of the bipolar disorder phenotype

Nick Craddock, Lisa Jones, Ian R Jones, George Kirov, Elaine K Green, Detelina Grozeva, Valentina Moskvina, Ivan Nikolov, Marian L Hamshere, Damjan Vukcevic, Sian Caesar, Katharine Gordon-Smith, Christine Fraser, Ellie Russell, Nadine Norton, Gerome Breen, David St Clair, David A Collier, Allan H Young, I Nicol Ferrier, Anne Farmer, Peter McGuffin, Peter A Holmans, Wellcome Trust Case Control Consortium (WTCCC), Peter Donnelly, Michael J Owen, Michael C O’Donovan

Mol Psychiatry. Author manuscript; available in PMC 2014 Mar 27.

Published in final edited form as: Mol Psychiatry. 2010 Feb; 15(2): 146–153. Published online 2008 Jul 1. doi: 10.1038/mp.2008.66