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Select item 110725061.

FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin

Bin Qiu, Zhaohui Zhong, Shawn Righter, Yuxue Xu, Jun Wang, Ran Deng, Chao Wang, Kent E. Williams, Yao-ying Ma, Gavriil Tsechpenakis, Tiebing Liang, Weidong Yong

Cell Mol Life Sci. 2022 Mar; 79(3): 175. Published online 2022 Mar 4. doi: 10.1007/s00018-022-04167-8

PMCID:: PMC11072506

Abstract Article PDF–8.7M

Select item 104046902.

MAP2 caps tau fibrils and inhibits aggregation

Michael R. Holden, Brad J. Krzesinski, Hilary A. Weismiller, Justin R. Shady, Martin Margittai

J Biol Chem. 2023 Jul; 299(7): 104891. Published online 2023 Jun 5. doi: 10.1016/j.jbc.2023.104891

PMCID:: PMC10404690

Abstract Article PDF–2.7M

Select item 103338843.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102324835.

Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules’ physical properties and neurite morphology

Kohei Nishida, Kosuke Matsumura, Miki Tamura, Takuto Nakamichi, Keiya Shimamori, Masahiro Kuragano, Arif Md. Rashedul Kabir, Akira Kakugo, Susumu Kotani, Naoki Nishishita, Kiyotaka Tokuraku

Sci Rep. 2023; 13: 8870. Published online 2023 May 31. doi: 10.1038/s41598-023-36073-9

PMCID:: PMC10232483

Abstract Article PDF–4.5M

Select item 99786356.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 99224687.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 95200378.

Specific phosphorylation of microtubule-associated protein 2c by extracellular signal–regulated kinase reduces interactions at its Pro-rich regions

Jitka Plucarová, Séverine Jansen, Subhash Narasimhan, Alice Laníková, Marc Lewitzky, Stephan M. Feller, Lukáš Žídek

J Biol Chem. 2022 Oct; 298(10): 102384. Published online 2022 Aug 17. doi: 10.1016/j.jbc.2022.102384

PMCID:: PMC9520037

Abstract Article PDF–1.2M

Select item 89739659.

Methyltransferase-like (METTL)14-mediated N6-methyladenosine modification modulates retinal pigment epithelial (RPE) activity by regulating the methylation of microtubule-associated protein (MAP)2

Lu Yin, Cong Ma, Shengping Hou, Xiang Ma

Bioengineered. 2022; 13(3): 4773–4785. Published online 2022 Feb 9. doi: 10.1080/21655979.2022.2032968

PMCID:: PMC8973965

Abstract Article PDF–5.5M

Select item 874895810.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 828000511.

The Cytoskeletal Elements MAP2 and NF-L Show Substantial Alterations in Different Stroke Models While Elevated Serum Levels Highlight Especially MAP2 as a Sensitive Biomarker in Stroke Patients

Bianca Mages, Thomas Fuhs, Susanne Aleithe, Alexandra Blietz, Constance Hobusch, Wolfgang Härtig, Stefan Schob, Martin Krueger, Dominik Michalski

Mol Neurobiol. 2021; 58(8): 4051–4069. Published online 2021 May 1. doi: 10.1007/s12035-021-02372-3

PMCID:: PMC8280005

Abstract Article PDF–5.1M

Select item 826502512.

Angiotensin II Induces Differentiation of Human Neuroblastoma Cells by Increasing MAP2 and ROS Levels

Bryan Jael Collazo, Dariana Morales-Vázquez, Jaylene Álvarez-Del Valle, Javier E. Sierra-Pagan, Juan Carlos Medina, Jarold Méndez-Álvarez, Yamil Gerena

J Renin Angiotensin Aldosterone Syst. 2021; 2021: 6191417. Published online 2021 Jun 14. doi: 10.1155/2021/6191417

PMCID:: PMC8265025

Abstract Article PDF–812K

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 802939514.

MAP2 Splicing is Altered in Huntington's Disease

Jorge Rubén Cabrera, José J. Lucas

Brain Pathol. 2017 Mar; 27(2): 181–189. Published online 2016 Jul 7. doi: 10.1111/bpa.12387

PMCID:: PMC8029395

Abstract Article PDF–511K

Select item 752672215.

Phosphorylated tau interactome in the human Alzheimer’s disease brain

Eleanor Drummond, Geoffrey Pires, Claire MacMurray, Manor Askenazi, Shruti Nayak, Marie Bourdon, Jiri Safar, Beatrix Ueberheide, Thomas Wisniewski

Brain. 2020 Sep; 143(9): 2803–2817. Published online 2020 Aug 19. doi: 10.1093/brain/awaa223

PMCID:: PMC7526722

Abstract Article PDF–1.1M

Select item 737208116.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245