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Select item 110120551.

FTO Positively Regulates Odontoblastic Differentiation via SMOC2 in Human Stem Cells from the Apical Papilla under Inflammatory Microenvironment

Qi Huang, Yumei Sun, Wushuang Huang, Fuping Zhang, Hongwen He, Yifan He, Fang Huang

Int J Mol Sci. 2024 Apr; 25(7): 4045. Published online 2024 Apr 5. doi: 10.3390/ijms25074045

PMCID:: PMC11012055

Abstract Article PDF–15M

Select item 110013222.

MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury

Chengjun Zhang, Ge Guan, Jiantao Wang, Haijian Wei, Jinzhen Cai

Ren Fail. 2023; 45(2): 2285869. Published online 2023 Dec 4. doi: 10.1080/0886022X.2023.2285869

PMCID:: PMC11001322

Abstract Article PDF–3.8M

Select item 109824623.

Efficacy of a Comprehensive Weight Reduction Intervention in Male Adolescents With Different FTO Genotypes

Zahra Roumi, Zahra Salimi, Zahra Mahmoudi, Khadijeh Abbasi Mobarakeh, Maryam Ladaninezhad, Mobina Zeinalabedini, Mohammad Keshavarz Mohammadian, Ali Shamsi‐Goushki, Zahra Saeedirad, Bojlul Bahar, Sara Khoshdooz, Naser Kalantari, Ghasem Azizi Tabesh, Saeid Doaei, Maryam Gholamalizadeh

Endocrinol Diabetes Metab. 2024 May; 7(3): e00483. Published online 2024 Mar 31. doi: 10.1002/edm2.483

PMCID:: PMC10982462

Abstract Article PDF–351K

Select item 109822254.

Fat mass and obesity-associated protein (FTO) mediated m⁶A modification of circFAM192A promoted gastric cancer proliferation by suppressing SLC7A5 decay

Xi Wu, Yuan Fang, Yunru Gu, Haoyang Shen, Yangyue Xu, Tingting Xu, Run Shi, Duo Xu, Jingxin Zhang, Kai Leng, Yongqian Shu, Pei Ma

Mol Biomed. 2024 Dec; 5: 11. Published online 2024 Apr 1. doi: 10.1186/s43556-024-00172-4

PMCID:: PMC10982225

Abstract Article PDF–5.9M

Select item 109816225.

circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis

Qingtao Liu, Pei Xu, Mingming Jin, Lei Wang, Fengqing Hu, Qi Yang, Rui Bi, Haibo Xiao, Lianyong Jiang, Fangbao Ding

Cancer Immunol Immunother. 2024 May; 73(5): 91. Published online 2024 Mar 30. doi: 10.1007/s00262-024-03634-4

PMCID:: PMC10981622

Abstract Article PDF–14M

Select item 108109386.

The m⁶A demethylase FTO targets POLQ to promote ccRCC cell proliferation and genome stability maintenance

Yichen He, Yimeng Chen, Zhengsheng Li, Changping Wu

J Cancer Res Clin Oncol. 2024; 150(2): 30. Published online 2024 Jan 25. doi: 10.1007/s00432-023-05541-0

PMCID:: PMC10810938

Abstract Article PDF–10M

Select item 107776557.

RNA N6-methyladenosine demethylase FTO targets MOXD1 promoting the malignant phenotype of gastric cancer

Yuexing Lai, Hairong Dong, Ping Xu, Jing Wang, Wen Feng, Zhenya Zhao, Linyu Sha

BMC Gastroenterol. 2024; 24: 29. Published online 2024 Jan 10. doi: 10.1186/s12876-023-03065-y

PMCID:: PMC10777655

Abstract Article PDF–12M

Select item 107549528.

Minor alleles of FTO rs9939609 and rs17817449 polymorphisms confer a higher risk of type 2 diabetes mellitus and dyslipidemia, but not coronary artery disease in a Chinese Han population

Youjin Zhang, Lvlin Chen, Junchen Zhu, Hao Liu, Luying Xu, Yang Wu, Chuan He, Yongyan Song

Front Endocrinol (Lausanne) 2023; 14: 1249070. Published online 2023 Dec 15. doi: 10.3389/fendo.2023.1249070

PMCID:: PMC10754952

Abstract Article PDF–739K

Select item 107138749.

FTO up‐regulation induced by MYC suppresses tumour progression in Epstein‒Barr virus‐associated gastric cancer

Yun‐Yun Xu, Ting Li, Ao Shen, Xiao‐Qiong Bao, Jin‐Fei Lin, Li‐Zhen Guo, Qi Meng, Dan‐Yun Ruan, Qi‐Hua Zhang, Zhi‐Xiang Zuo, Zhao‐lei Zeng

Clin Transl Med. 2023 Dec; 13(12): e1505. Published online 2023 Dec 11. doi: 10.1002/ctm2.1505

PMCID:: PMC10713874

Abstract Article PDF–15M

Select item 1068862310.

Type 2 diabetes linked FTO gene variant rs8050136 is significantly associated with gravidity in gestational diabetes in a sample of Bangladeshi women: Meta-analysis and case-control study

U. S. Mahzabin Amin, Tahia Anan Rahman, Mashfiqul Hasan, Tania Tofail, Muhammad Abul Hasanat, Zeba I. Seraj, Md Salimullah

PLoS One. 2023; 18(11): e0288318. Published online 2023 Nov 30. doi: 10.1371/journal.pone.0288318

PMCID:: PMC10688623

Abstract Article PDF–2.6M

Select item 1066816111.

Genetic variant rs9939609 in FTO is associated with body composition and obesity risk in Korean females

Hyeon-Gyo Park, Jeong-Hwa Choi

BMJ Open Diabetes Res Care. 2023; 11(6): e003649. Published online 2023 Nov 22. doi: 10.1136/bmjdrc-2023-003649

PMCID:: PMC10668161

Abstract Article PDF–472K

Select item 1062527512.

Advanced glycation end products impair bone marrow mesenchymal stem cells osteogenesis in periodontitis with diabetes via FTO-mediated N⁶-methyladenosine modification of sclerostin

Jie Zhou, Yanlin Zhu, Dongqing Ai, Mengjiao Zhou, Han Li, Guangyue Li, Leilei Zheng, Jinlin Song

J Transl Med. 2023; 21: 781. Published online 2023 Nov 4. doi: 10.1186/s12967-023-04630-5

PMCID:: PMC10625275

Abstract Article PDF–3.2M

Select item 1062376813.

FTO facilitates cancer metastasis by modifying the m⁶A level of FAP to induce integrin/FAK signaling in non-small cell lung cancer

Lirong Gao, Anqi Wang, Yuling Chen, Xin Cai, Yue Li, Jian Zhao, Yang Zhang, Weijie Zhang, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu, Jian-an Huang

Cell Commun Signal. 2023; 21: 311. Published online 2023 Nov 2. doi: 10.1186/s12964-023-01343-6

PMCID:: PMC10623768

Abstract Article PDF–13M

Select item 1062023914.

FTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC

Jin Lu, Yongsheng Yang, Xiangliang Liu, Xiao Chen, Wei Song, Zefeng Liu

Cell Death Dis. 2023 Nov; 14(11): 713. Published online 2023 Nov 1. doi: 10.1038/s41419-023-06244-7

PMCID:: PMC10620239

Abstract Article PDF–7.2M

Select item 1056587615.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1052154116.

Role of rs9939506 polymorphism of FTO gene in resistance to eating in male adolescents

Ali Shaker, Soheila Shekari, Mobina Zeinalabedini, Zahra Salimi, Zahra Roumi, Khadijeh Abbasi Mobarakeh, Ali Shamsi-Goushki, Mohammad Masoumvand, Mohammad Keshavarz Mohammadian, Pegah Samani, Ghasem Azizi-Tabesh, Hanieh Shafaei, Saeid Doaei, Naser Kalantari, Maryam Gholamalizadeh

BMC Pediatr. 2023; 23: 486. Published online 2023 Sep 26. doi: 10.1186/s12887-023-04310-9

PMCID:: PMC10521541

Abstract Article PDF–1014K

Select item 1050074117.

Association of FTO gene variant rs9939609 with polycystic ovary syndrome from Gujarat, India

Hiral Chaudhary, Jalpa Patel, Nayan K. Jain, Sonal Panchal, Naresh Laddha, Rushikesh Joshi

BMC Med Genomics. 2023; 16: 216. Published online 2023 Sep 14. doi: 10.1186/s12920-023-01654-0

PMCID:: PMC10500741

Abstract Article PDF–1.0M

Select item 1049627518.

Dietary approach to stop hypertension and healthy eating index 2015, modify the association between FTO polymorphisms and obesity phenotypes

Firoozeh Hosseini-Esfahani, Mahshid Rezaei, Glareh Koochakpoor, Maryam S. Daneshpour, Parvin Mirmiran, Fereidoun Azizi

BMC Res Notes. 2023; 16: 204. Published online 2023 Sep 11. doi: 10.1186/s13104-023-06463-3

PMCID:: PMC10496275

Abstract Article PDF–954K

Select item 1040574919.

FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner

Zhuang Sun, Xiaolu Sun, Guoliang Qin, Yi Li, Guanwen Zhou, Xianzhou Jiang

Epigenetics. 2023; 18(1): 2242688. Published online 2023 Aug 4. doi: 10.1080/15592294.2023.2242688

PMCID:: PMC10405749

Abstract Article PDF–3.1M

Select item 1040437520.

The effect of FTO gene rs9939609 polymorphism on the association between colorectal cancer and different types of dietary fat intake: a case-control study

Azadeh Hajipour, Naeemeh Hassanpour Ardekanizadeh, Zahra Roumi, Soheila Shekari, Bahareh Aminnezhad Kavkani, Seyedeh Hayedeh Mousavi Shalmani, Bojlul Bahar, Shirin Tajadod, Marjan Ajami, Ghasem Azizi Tabesh, Maryam Gholamalizadeh, Saeid Doaei

J Physiol Anthropol. 2023; 42: 17. Published online 2023 Aug 5. doi: 10.1186/s40101-023-00333-4