PMC Links for GEO Profiles (Select 132571041) - PMC

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103126744.

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker

Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560

Published in:: Mol Syst Biol. 2024 Apr; 20(4): 428–457.

PMCID:: PMC10312674

Abstract Article PDF–9.6M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99085556.

Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex

Bon Seong Goo, Dong Jin Mun, Seunghyun Kim, Truong Thi My Nhung, Su Been Lee, Youngsik Woo, Soo Jeong Kim, Bo Kyoung Suh, Sung Jin Park, Hee-Eun Lee, Kunyou Park, Hyunsoo Jang, Jong-Cheol Rah, Ki-Jun Yoon, Seung Tae Baek, Seung-Yeol Park, Sang Ki Park

Mol Psychiatry. 2023; 28(2): 856–870. Published online 2022 Nov 10. doi: 10.1038/s41380-022-01856-5

PMCID:: PMC9908555

Abstract Article PDF–6.7M

Select item 98491417.

A proteome-scale map of the SARS-CoV-2–human contactome

Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun

Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z

PMCID:: PMC9849141

Abstract Article PDF–7.1M

Select item 98117868.

Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Aleksandr V. Sokolov, Diana-Maria Manu, Didi O. T. Nordberg, Adrian D. E. Boström, Jussi Jokinen, Helgi B. Schiöth

Clin Epigenetics. 2023; 15: 1. Published online 2023 Jan 4. doi: 10.1186/s13148-022-01394-5

PMCID:: PMC9811786

Abstract Article PDF–3.6M

Select item 96297409.

Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility

Carolina Villarroya-Beltri, Ana Osorio, Raúl Torres-Ruiz, David Gómez-Sánchez, Marianna Trakala, Agustin Sánchez-Belmonte, Fátima Mercadillo, Begoña Hurtado, Borja Pitarch, Almudena Hernández-Núñez, Antonio Gómez-Caturla, Daniel Rueda, José Perea, Sandra Rodríguez-Perales, Marcos Malumbres, Miguel Urioste

Sci Adv. 2022 Nov; 8(44): eabq5914. Published online 2022 Nov 2. doi: 10.1126/sciadv.abq5914

PMCID:: PMC9629740

Abstract Article PDF–3.6M

Select item 949171310.

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li

Sci Adv. 2022 Sep; 8(38): eabq4831. Published online 2022 Sep 21. doi: 10.1126/sciadv.abq4831

PMCID:: PMC9491713

Abstract Article PDF–12M

Select item 939272411.

Schizophrenia-associated differential DNA methylation in brain is distributed across the genome and annotated to MAD1L1, a locus at which DNA methylation and transcription phenotypes share genetic variation with schizophrenia risk

Brandon C. McKinney, Lora L. McClain, Christopher M. Hensler, Yue Wei, Lambertus Klei, David A. Lewis, Bernie Devlin, Jiebiao Wang, Ying Ding, Robert A. Sweet

Transl Psychiatry. 2022; 12: 340. Published online 2022 Aug 20. doi: 10.1038/s41398-022-02071-0

PMCID:: PMC9392724

Abstract Article PDF–1.7M

Select item 939206312.

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li

Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z

PMCID:: PMC9392063

Abstract Article PDF–2.0M

Select item 927928513.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 926261414.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 899785615.

The Sin3A/MAD1 Complex, through Its PAH2 Domain, Acts as a Second Repressor of Retinoic Acid Receptor Beta Expression in Breast Cancer Cells

Nisha Rani Dahiya, Boris A. Leibovitch, Rama Kadamb, Nidhi Bansal, Samuel Waxman

Cells. 2022 Apr; 11(7): 1179. Published online 2022 Mar 31. doi: 10.3390/cells11071179

PMCID:: PMC8997856

Abstract Article PDF–2.5M

Select item 841874716.

MAD1L1 and TSNARE gene polymorphisms are associated with schizophrenia susceptibility in the Han Chinese population

Xianglai Liu, Hailing Xie, Zejuan Fu, Qiankun Yao, Tianming Han, Dafei Zhan, Zhan Lin, Hong Zhu

BMC Med Genomics. 2021; 14: 218. Published online 2021 Sep 4. doi: 10.1186/s12920-021-01070-2

PMCID:: PMC8418747

Abstract Article PDF–974K

Select item 839110417.

Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1

Elyse S Fischer, Conny W H Yu, Dom Bellini, Stephen H McLaughlin, Christian M Orr, Armin Wagner, Stefan M V Freund, David Barford

EMBO Rep. 2021 Jul 5; 22(7): e52242. Published online 2021 May 19. doi: 10.15252/embr.202052242

PMCID:: PMC8391104

Abstract Article PDF–3.1M

Select item 837314218.

The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF

Matthew Jessulat, Shahreen Amin, Mohsen Hooshyar, Ramy Malty, Mohamed Taha Moutaoufik, Mara Zilocchi, Zoe Istace, Sadhna Phanse, Hiroyuki Aoki, Katayoun Omidi, Daniel Burnside, Bahram Samanfar, Khaled A Aly, Ashkan Golshani, Mohan Babu

Nucleic Acids Res. 2021 Aug 20; 49(14): 8145–8160. Published online 2021 Jul 9. doi: 10.1093/nar/gkab585

PMCID:: PMC8373142

Abstract Article PDF–2.0M

Select item 818479619.

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel, Najla El-Hachem, Frédéric Soysouvanh, Hanene Hadhiri-Bzioueche, Serena Giuliano, Sophie Nguyen, Pavel Horák, Anne-Sophie Gay, Delphine Debayle, Nicolas Nottet, Guillaume Béranger, Brigitte Bressac-de Paillerets, Corine Bertolotto, Robert Ballotti

Cell Death Differ. 2021 Jun; 28(6): 1837–1848. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00710-x

PMCID:: PMC8184796

Abstract Article PDF–2.4M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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